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Children and COVID-19 Research Library

UNICEF Innocenti's curated library of COVID-19 + Children research

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31 - 44 of 44
Humoral immunity to SARS-CoV-2 and seasonal coronaviruses in children and adults in north-eastern France

AUTHOR(S)
Tom Woudenberg; Stephane Pelleau; Francois Anna (et al.)

Published: July 2021   Journal: EBioMedicine Home
Children are underrepresented in the COVID-19 pandemic and often experience milder disease than adolescents and adults. Reduced severity is possibly due to recent and more frequent seasonal human coronaviruses (HCoV) infections. This study assessed the seroprevalence of SARS-CoV-2 and seasonal HCoV specific antibodies in a large cohort in north-eastern France. In this cross-sectional seroprevalence study, serum samples were collected from children and adults requiring hospital admission for non-COVID-19 between February and August 2020. Antibody responses to SARS-CoV-2 and seasonal HCoV (229E, HKU1, NL63, OC43) were assessed using a bead-based multiplex assay, Luciferase-Linked ImmunoSorbent Assay, and a pseudotype neutralisation assay.
Assessment of SARS-CoV-2 testing in children during a low prevalence period (VIGIL study 1)

AUTHOR(S)
Eleonore Eskander; Camille Jung; Corinne Levy (et al.)

Published: July 2021   Journal: Infectious Diseases Now

SARS-CoV-2 induces a broad spectrum of clinical manifestations, which overlap with other viral infections very common in children. This study aimed to describe the percentage of positive SARS-CoV-2 RT-PCR tests in symptomatic and asymptomatic ambulatory children and to determine the predictive factors for positivity. From June 1 to July 31, 2020,  a cross-sectional prospective, multicenter study (13 hospital emergency units and 59 ambulatory pediatricians) was conducted throughout France. Children under 15 years of age with a prescription of nasopharyngeal SARS-CoV-2 RT-PCR test were enrolled.

Epidemiological analysis of burn injuries in children during the first COVID-19 lockdown, and a comparison with the previous five years

AUTHOR(S)
O. Charvillat; M.-C. Plancq; E. Haraux (et al.)

Published: July 2021   Journal: Annales de Chirurgie Plastique Esthétique

Child burns rank among the most frequent domestic accidents in France. COVID-19 lockdown between March 16th and May 11th of 2020 increased time spent at home by children. This retrospective, observational study described the epidemiological impact of COVID-19 lockdown on child burns in a pediatric surgery department compared with previous five years. Child burns in the previous five years constituted the “before COVID-19 group” as the reference group. Child burns during the first lockdown formed the “COVID-19 group”. Demographics characteristics, the delay before first attendance at the surgery department, burns characteristics, the place of the incident, need of skin graft, and child reactions to trauma or isolation were recorded for these two groups.

COVID-19 and parental burnout: parents locked down but not more exhausted

AUTHOR(S)
Sarah Le Vigouroux; Astrid Lebert-Charron; Jaqueline Wendland (et al.)

Published: July 2021   Journal: Journal of Family Issues
Lockdowns put in place in response to the COVID-19 health crisis have changed daily functioning for families and potentially the emotional experience of individuals in their parenting role. Our study aimed to highlight the importance of the environmental consequences associated with lockdowns on parental burnout. It compared data on parental burnout levels from two French samples: the first collected in 2018 (N = 1332) and the second collected during the last month of lockdown (N = 522).
Pediatric infectious disease group (GPIP) position paper on the immune debt of the COVID-19 pandemic in childhood, how can we fill the immunity gap?

AUTHOR(S)
Robert Cohen; Marion Ashman; Muhamed-Kheir Taha (et al.)

Published: May 2021   Journal: Infectious Diseases Now
Since the beginning of the COVID-19 pandemic, reduced incidence of many viral and bacterial infections has been reported in children: bronchiolitis, varicella, measles, pertussis, pneumococcal and meningococcal invasive diseases. The purpose of this opinion paper is to discuss various situations that could lead to larger epidemics when the non-pharmaceutical interventions (NPI) imposed by the SARS-CoV-2 epidemic will no longer be necessary.
COVID-19 in children at Strasbourg University Hospital: a retrospective study of the first 2 months of the epidemic

AUTHOR(S)
O. Lavaine; J. Spizzo; C. Arbitre (et al.)

Published: April 2021   Journal: Archives de Pédiatrie

The emergence and rapid spread of coronavirus disease 2019 (COVID-19) have shaken the planet, both in terms of health and economical aspects, constituting a real challenge for the scientific community. At the time of the arrival of the epidemic in France, there were limited data regarding how COVID-19 could affect children. A lesser severity compared with adults was described, but knowledge concerning clinical forms and screening strategies was missing. This retrospective and non-interventional epidemiological study aimed to describe the epidemiology and the clinical features of COVID-19 pediatric disease in the first university hospital affected by the epidemic in France.

Risk and protective factors related to children’s symptoms of emotional difficulties and hyperactivity/inattention during the COVID-19-related lockdown in France: results from a community sample

AUTHOR(S)
Flore Moulin; Tarik El‑Aarbaoui; Joel José Herranz Bustamante (et al.)

Published: March 2021   Journal: European Child & Adolescent Psychiatry
The COVID-19 epidemic has spread worldwide since December 2019. To contain it, preventive measures including social distancing, economic shutdown, and school closures were introduced, carrying the risk of mental health burden in adults and children. Although the knowledge base regarding children’s response to trauma and adverse events in general has broadened, descriptions of their mental health during epidemics remain scarce. In particular, the role of family socioeconomic characteristics and parental mental health are poorly understood.
Modelling safe protocols for reopening schools during the COVID-19 pandemic in France

AUTHOR(S)
Laura Di Domenico; Giulia Pullano; Chiara E. Sabbatini

Published: February 2021   Journal: Nature Communications
As countries in Europe implement strategies to control the COVID-19 pandemic, different options are chosen regarding schools. Through a stochastic age-structured transmission model calibrated to the observed epidemic in Île-de-France in the first wave, this study explored scenarios of partial, progressive, or full school reopening. Given the uncertainty on children’s role, we found that reopening schools after lockdown may increase COVID-19 cases, yet protocols exist to keep the epidemic controlled. Under a scenario with stable epidemic activity if schools were closed, reopening pre-schools and primary schools would lead to up to 76% [67, 84]% occupation of ICU beds if no other school level reopened, or if middle and high schools reopened later. Immediately reopening all school levels may overwhelm the ICU system.
Child eating behaviors, parental feeding practices and food shopping motivations during the COVID-19 lockdown in France: (how) did they change?

AUTHOR(S)
Kaat Philippe; Claire Chabanet; Sylvie Issanchou (et al.)

Published: January 2021   Journal: Appetite
The COVID-19 pandemic caused France to impose a strict lockdown, affecting families' habits in many domains. This study evaluated possible changes in child eating behaviors, parental feeding practices, and parental motivations when buying food during the lockdown, compared to the period before the lockdown.
Comparison of the characteristics, morbidity, and mortality of COVID-19 and seasonal influenza: a nationwide, population-based retrospective cohort study

AUTHOR(S)
Lionel Piroth; Jonathan Cottenet; Anne-Sophie Mariet (et al.)

Published: December 2020   Journal: The Lancet Respiratory Medicine
To date, influenza epidemics have been considered suitable for use as a model for the COVID-19 epidemic, given that they are respiratory diseases with similar modes of transmission. However, data directly comparing the two diseases are scarce. This study did a nationwide retrospective cohort study using the French national administrative database (PMSI), which includes discharge summaries for all hospital admissions in France. All patients hospitalised for COVID-19 from March 1 to April 30, 2020, and all patients hospitalised for influenza between Dec 1, 2018, and Feb 28, 2019, were included.
Cite this research | Open access | No. of pages: 9 | Language: English | Topics: Health | Tags: child health, COVID-19, epidemiology, hospitalization, infectious disease | Countries: France
Learning at home: distance learning solutions and child development during the COVID-19 lockdown

AUTHOR(S)
Hugues Champeaux; Lucia Mangiavacchi; Francesca Marchetta

Published: October 2020
School closures, forced by the COVID-19 crisis in many countries, impacted on children’s lives and their learning process. There will likely be substantial and persistent disparities between families in terms of educational outcomes. Distant learning solutions adopted by schools have been heterogeneous over countries, within countries and between school levels. As a consequence, most of the burden of children’s learning fell on their parents, with likely uneven results depending on the socio-economic characteristics of the family. Using a real time survey data collected in April 2020 and early May in France and Italy, this study estimates child fixed effects models to analyze how the lockdown has affected children’s emotional wellbeing and their home learning process. The analysis also focuses on the role played by online classes or other interactive methods on children’s home learning and emotional status.
The wide spectrum of COVID-19 clinical presentation in children

AUTHOR(S)
Nadia Nathan; Blandine Prevost; Chiara Sileo (et al.)

Published: September 2020   Journal: Journal of Clinical Medicine
 Ten months after its appearance in December 2019, SARS-CoV-2 has infected more than 25 million patients worldwide. Because children were first identified as potential spreaders of the virus, schools were closed in several countries. However, it rapidly became evident that the number of hospitalized children infected by SARS-CoV-2 was dramatically lower than that of adults. To date, only hypotheses have been raised to explain this difference, so it is of great importance to describe the presentation of this disease among children. This study describes a wide spectrum of COVID-19 manifestation in children in a dedicated pediatric unit in France.
Emerging health challenges for children with physical disabilities and their parents during the COVID-19 pandemic: the ECHO French survey

AUTHOR(S)
Marine Cacioppo; Sandra Bouvier; Rodolphe Bailly (et al.)

Published: August 2020   Journal: Annals of Physical and Rehabilitation Medicine

The daily lives of children with physical disabilities and their families have been significantly affected by the COVID-19 pandemic. The children face health risks, especially mental, behavioral, social and physical risks. This study aimed to identify potential healthcare issues relating to the wellbeing of disabled children, continuity of rehabilitation and medical care, and parental concerns during the COVID-19 lockdown.

Emergence of Kawasaki disease related to SARS-CoV-2 infection in an epicentre of the French COVID-19 epidemic: a time-series analysis

AUTHOR(S)
Naim Ouldali Ouldali; Marie Pouletty; Patricia Mariani (et al.)

Published: July 2020   Journal: The Lancet Child & Adolescent Health
Kawasaki disease is an acute febrile systemic childhood vasculitis, which is suspected to be triggered by respiratory viral infections. This study aims to examine whether the ongoing COVID-19 epidemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is associated with an increase in the incidence of Kawasaki disease.
Cite this research | Open access | Vol.: 4 | Issue: 9 | No. of pages: 662-668 | Language: English | Topics: Health | Tags: child health, COVID-19, infectious disease | Countries: France
31 - 44 of 44

UNICEF Innocenti's Children and COVID-19 Library is a database collecting research from around the world on COVID-19 and its impacts on children and adolescents.

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COVID-19 & Children: Rapid Research Response

UNICEF Innocenti is mobilizing a rapid research response in line with UNICEF’s global response to the COVID-19 crisis. The initiatives we’ve begun will provide the broad range of evidence needed to inform our work to scale up rapid assessment, develop urgent mitigating strategies in programming and advocacy, and preparation of interventions to respond to the medium and longer-term consequences of the COVID-19 crisis. The research projects cover a rapid review of evidence, education analysis, and social and economic policies.