Multisystem inflammatory syndrome associated with COVID-19 in children in Pakistan
Masood Sadiq; Omeir Ali Aziz; Uzma Kazmi (et al.)
Published: October 2020
Journal: The Lancet Child & Adolescent Health
The knowledge of COVID-19 is evolving with new aspects of the disease continuing to emerge. Children and adolescents younger than 20 years of age constitute 10·6% of the total reported confirmed cases of COVID-19 in Pakistan
as of July 8, 2020, with a mortality of 0·3% for those aged 10 years or younger and 0·5% for those aged 11–20 years. Multisystem inflammatory syndrome in children (MIS-C), also known as paediatric inflammatory multisystem syndrome temporally associated with severe acute respiratory syndrome coronavirus 2 (PIMS-TS) is being reported primarily from Europe and the USA. Many of these children meet the criteria for complete or incomplete Kawasaki disease, but different clinical presentations of this inflammatory disorder are being reported. The ethnic origin of reported cases show that Black, Hispanic, and Asian children might be disproportionally affected. Similarly, unlike Kawasaki disease, these cases have occurred in older children and adolescents.