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UNDER DEVELOPMENT UNICEF Innocenti's curated library of COVID-19 + Children research

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Journal article

Increased risk of rhinovirus infection in children during the coronavirus disease‐19 pandemic

AUTHOR(S)
Emi Takashita; Chiharu Kawakami ; Tomoko Momoki (et al.)

Published: March 2021 Journal: Influenza and Other Respiratory Viruses

Coronavirus disease (COVID‐19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), was first detected in Japan in January 2020 and has spread throughout the country. Previous studies have reported that viral interference among influenza virus, rhinovirus, and other respiratory viruses can affect viral infections at the host and population level. To investigate the impact of COVID‐19 on influenza and other respiratory virus infections, this study analyzed clinical specimens collected from 2244 patients in Japan with respiratory diseases between January 2018 and September 2020.

Journal article

High rates of antibiotic prescriptions in children with COVID‐19 or multisystem inflammatory syndrome: a multinational experience in 990 cases from Latin America

AUTHOR(S)
Adriana Yock- Corrales; Jacopo Lenzi; Rolando Ulloa- Gutiérrez (et al.)

Published: March 2021 Journal: Acta Paediatrica

This study aims to assess rates of antibiotic prescriptions and its determinants in in children with COVID‐19 or Multisystem Inflammatory Syndrome (MIS‐C). Children <18 years‐old assessed in five Latin Americas countries with a diagnosis of COVID‐19 or MIS‐C were enrolled. Antibiotic prescriptions and factors associated with their use were assessed.

Evidence Synthesis and other Reviews

Risk profiles of severe illness in children with COVID-19: a meta-analysis of individual patients

AUTHOR(S)
Bo Zhou; Yuan Yuan; Shunan Wang (et al.)

Published: March 2021 Journal: Pediatric Research

We prepared a meta-analysis on case reports in children with COVID-19, aiming to identify potential risk factors for severe illness and to develop a prediction model for risk assessment. Literature retrieval, case report selection, and data extraction were independently completed by two authors. STATA software (version 14.1) and R programming environment (v4.0.2) were used for data handling.

Journal article

Care of hospitalized infants and their families during the COVID-19 pandemic: an international survey

AUTHOR(S)
Ita Litmanovitz; Dalia Silberstein; Samantha Butler (et al.)

Published: March 2021 Journal: Journal of Perinatology

This research study explored changes in family-centered care practices for hospitalized infants and families due to the COVID-19 pandemic. This exploratory descriptive study used a 49-item online survey, distributed to health care professionals working with hospitalized infants and families. The sample consisted of 96 participants from 22 countries.

Cite this research | Open access | No. of pages: 7 | Language: English | Tags: child health, family assistance, health services, COVID-19, hospitalization

Journal article

The interplay between environmental exposures and COVID-19 risks in the health of children

AUTHOR(S)
Peter D. Sly; Brittany A. Trottier; Catherine M. Bulka

Published: March 2021 Journal: Environmental Health volume

An unusual feature of SARS-Cov-2 infection and the COVID-19 pandemic is that children are less severely affected than adults. This is especially paradoxical given the epidemiological links between poor air quality and increased COVID-19 severity in adults and that children are generally more vulnerable than adults to the adverse consequences of air pollution. This study aims o identify gaps in knowledge about the factors that protect children from severe SARS-Cov-2 infection even in the face of air pollution, and to develop a transdisciplinary research strategy to address these gaps.

Journal article

Pediatric routine vaccinations in the COVID 19 lockdown period: the survey of the Italian Pediatric Society

AUTHOR(S)
Rocco Russo; Elena Bozzola; Paolo Palma (et al.)

Published: March 2021 Journal: Italian Journal of Pediatrics

COVID-19 pandemic was responsible for disrupting routine immunization activities all over the world. Aim of the study was to investigate the reduced adherence to the national children vaccination schedule during the lockdown period in Italy. Through social channels, the Italian Pediatric Society conducted a survey among Italian families on children vaccination during lockdown period.

Journal article

The severity and atypical presentations of COVID-19 infection in pediatrics

AUTHOR(S)
Nagwan Y. Saleh; Hesham M. Aboelghar; Sherif S. Salem (et al.)

Published: March 2021 Journal: BMC Pediatrics

Emergence of 2019-nCoV attracted global attention and WHO declared COVID-19 a public health emergency of international concern. Therefore this study aimed to explore the severity and atypical manifestations of COVID-19 among children. This is an observational cohort study conducted on 398 children with confirmed COVID-19 by using realtime reverse transcriptase polymerase chain reaction assay for detection of 2019-nCoV nucleic acid during the period from March to November 2020. Patients were subdivided regarding the severity of COVID-19 presentation into Group I (Non-severe COVID-19) was admitted into wards and Group II (Severe COVID-19) admitted into the PICU.

Journal article

Future vaccinations in pregnancy

AUTHOR(S)
D. Vress

Published: March 2021 Journal: Best Practice & Research Clinical Obstetrics & Gynaecology

Vaccination in pregnancy provides an important opportunity to target illnesses that are known to impact particularly on pregnant women, fetal development and cause newborn illness. The ability to create antibodies via safe vaccination that cross the placenta can provide protection against maternal, congenital and newborn infection. There are currently multiple vaccines being developed which have direct benefits for pregnant women and their newborns. Group B Streptococcus, Respiratory Syncytial Virus, Cytomegalovirus, Zika, Ebola, Malaria and coronavirus SARS-CoV-2 are all being researched with the view to developing a safe vaccine available for pregnant women. There is also an increased movement towards including pregnant women in vaccine development and trials, challenging the historical, ethical and medicolegal arguments against their involvement in such research.

Journal article

Outcomes of newborns to mothers with COVID-19

AUTHOR(S)
K. Ghema; M. Lehlimi; H. Toumi (et al.)

Published: March 2021 Journal: Infectious Diseases Now

Coronavirus disease 2019 (COVID-19) has spread rapidly across the world. Given the sharply increased infection rate, the number of pregnant women and children with COVID-19 is correspondingly on the rise. SARS-CoV-2 infection is transmitted through droplets; though hypothesized, other transmission routes have not been confirmed. As of now, it remains unclear whether and how SARS-CoV-2 can possibly be transmitted from the mother to the fetus. This study examines the medical records of 30 neonates born to women with COVID-19, the objective being to provide documented information on maternal-child transmission and infant outcomes.

Journal article

COVID-19 management in pediatrics

AUTHOR(S)
Magalie L. Alcindor; FitzGerald Alcindor; Kristy E. Richard

Published: March 2021 Journal: The Journal for Nurse Practitioners

Coronavirus disease 2019 (COVID-19) is a deadly global pandemic, with scientific efforts improving our understanding of this novel coronavirus. No proven disease-specific therapies exist, although 2 vaccines have been recently approved by the United States Food and Drug Administration under emergency use authori-zation, and several others are in development or phase III clinical trial testing. COVID-19 presents in greater severity in the medically fragile, obese, elderly, and socially disadvantaged, and children in general are less affected. All children are at risk, but those with comorbidities and neonates are more susceptible. The multisystem inflammatory syndrome is a severe version which can present in any child with a recent COVID-19 infection. The face of the pandemic has been changing in the last few months, with recent increasing cases,virus mutations, and onset of vaccination. This article provides COVID-19 management for children and adolescents and implications for nursing and advanced practice providers.

Journal article

School attendance, asthma risk, and COVID-19 in children

AUTHOR(S)
Elissa M. Abrams; Marcus Shaker; Matthew Greenhawt (et al.)

Published: March 2021

In the face of tremendous uncertainty during the current pandemic, there is a need for clear and consistent recommendations and an understanding of the evidence in general, and for families of children with allergic conditions. A common concern of parents of children with asthma is the risk that in-person learning poses during the pandemic. This Rostrum examines the actual risk of in-person learning among children with asthma during novel coronavirus disease 2019 (COVID-19), the discrepancy between perceived and actual risk, the contributing factors to this discrepancy, and possible solutions to narrow this divide.

Journal article

Demographic, psychological, and experiential correlates of SARS-CoV-2 vaccination intentions in a sample of Canadian families

AUTHOR(S)
Christine L. Lackner; Charles H. Wang

Published: March 2021 Journal: Vaccine: X

The COVID-19 pandemic has been ongoing for close to a year, with second waves occurring presently and many viewing vaccine uptake as the most likely way to curb successive waves and promote herd immunity. Reaching herd immunity status likely necessitates that children, as well as their parents, receive a vaccine targeting SARS-CoV-2. This exploratory study investigated the demographic, experiential, and psychological factors associated with the anticipated likelihood and speed of having children receive a SARS-CoV-2 vaccine in a sample of 455 Canadian families (858 children; parents’ mean age = 38.2 ± 6.82 years).

Commentaries and Think Pieces

Post-disruption catch-up of child immunisation and health-care services in Bangladesh

AUTHOR(S)
Shohel Rana; Rashed Shah; Sabbir Ahmed (et al.)

Published: March 2021 Journal: The Lancet Infectious Diseases

After the first COVID-19 case was diagnosed in March, 2020, child health service delivery and use declined in rural remote communities in Bangladesh. This paper retrieved annual data for 2019 and 2020 from Bangladesh's district health information system (DHIS) for child immunisation and sick children's care-seeking in six subdistricts of Barishal, Bangladesh.

Journal article

SARS-CoV-2 infection and transmission in primary schools in England in June–December, 2020 (sKIDs): an active, prospective surveillance study

AUTHOR(S)
Shamez N. Ladhani; Frances Baawuah; Joanne Beckmann (et al.)

Published: March 2021 Journal: The Lancet Child & Adolescent Health

Little is known about the risk of SARS-CoV-2 infection and transmission in educational settings. Public Health England initiated a study, COVID-19 Surveillance in School KIDs (sKIDs), in primary schools when they partially reopened from June 1, 2020, after the first national lockdown in England to estimate the incidence of symptomatic and asymptomatic SARS-CoV-2 infection, seroprevalence, and seroconversion in staff and students.

Journal article

Prevalence of RT-qPCR-detected SARS-CoV-2 infection at schools: first results from the Austrian School-SARS-CoV-2 prospective cohort study

AUTHOR(S)
Peter Willeit; Robert Krause; Bernd Lamprecht

Published: March 2021 Journal: The Lancet Regional Health - Europe Log inRegister RESEAR

The role of schools in the SARS-CoV-2 pandemic is much debated. We aimed to quantify reliably the prevalence of SARS-CoV-2 infections at schools detected with reverse-transcription quantitative polymerase-chain-reaction (RT-qPCR). This nationwide prospective cohort study monitors a representative sample of pupils (grade 1–8) and teachers at Austrian schools throughout the school year 2020/2021. It repeatedly tested participants for SARS-CoV-2 infection using a gargling solution and RT-qPCR and herein reported on the first two rounds of examinations.

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UNICEF Innocenti's Children and COVID-19 Library is a database collecting research from around the world on COVID-19 and its impacts on children and adolescents.

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