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Children and COVID-19 Research Library

UNICEF Innocenti's curated library of COVID-19 + Children research

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Predictive value of cardiac markers in the prognosis of COVID-19 in children

Ufuk Utku Güllü; Şükrü Güngör; Sevcan İpek

Published: July 2021   Journal: The American Journal of Emergency Medicine
Occasionally, children with COVID-19 may develop arrhythmia, myocarditis, and cardiogenic shock involving multisystemic inflammatory syndrome in children (MIS-C). This study aimed to identify the laboratory parameters that may predict early cardiovascular involvement in these patients.
Cite this research | Open access | Vol.: 43 | No. of pages: 307-311 | Language: English | Topics: Health | Tags: child health, COVID-19, Heart diseases, infectious disease
Impact of COVID-19 on pediatric clinical research

Nhu N. Tran; Michelle Tran; Jeraldine Lopez (et al.)

Published: June 2021   Journal: Journal of Pediatric Nursing
Many public institutions and settings have taken action to limit exposure to and slow the spread of the novel coronavirus (COVID-19). This paper sought to characterize the impact of stay-at-home orders on the study of cerebral autoregulation and its association with developmental delays in infants with congenital heart disease compared with healthy controls.
COVID-19 disease during pregnancy and peripartum period: a cardiovascular review

Sedighe Hantoushzadeh; Seyedeh Maedeh Nabavian; Zahra Soleimani (et al.)

Published: May 2021   Journal: Current Problems in Cardiology
Pregnancy with various physiological effects on cardiovascular system, makes mothers with borderline cardiovascular reserve at significant risk for adverse events during labor and early postpartum period. Cardiac imaging modalities, have shown that COVID-19 disease is associated with subclinical myocardial injury in significant numbers of infected people, even in mild or asymptomatic disease and previous healthy ones. Herein, this study have discussed the cardiovascular aspects of prepartum pregnant women with COVID-19 disease, especially patients with moderate to severe illness. Also, it has proposed how to handle the hemodynamic load during labor and the first 48 hours postpartum in the hypoxemic overloaded parturients with possible subclinical myocardial injury.
Responding to non-communicable diseases during and beyond the COVID-19 pandemic

This brief provides guidance for governments, policymakers, UN agencies and development partners to address non-communicable diseases (NCDs) as an integral part of the COVID-19 response and in broader efforts for achieving the 2030 Agenda for Sustainable Development. NCDs, such as cardiovascular disease, cancer, diabetes and chronic respiratory disease, are amplifying the impacts of COVID-19, and COVID-19 is exacerbating the burden of NCDs, particularly in already disadvantaged communities. Almost one fourth (22%) of the global population is estimated to have an underlying condition that increases their vulnerability to COVID-19, and most of these conditions are NCDs. Urgent action across sectors is needed to address the root causes of NCDs and increase access to affordable and quality treatments and prevention.

Children’s heart and COVID-19: up-to-date evidence in the form of a systematic review

Giulia Sanna; Pier Paolo Bassareo

Published: May 2020   Journal: European Journal of Pediatrics

The new coronavirus disease outbreak in 2019 (COVID-19) represents a dramatic challenge for healthcare systems worldwide. As to viral tropism, lungs are not the only COVID-19 target but also the heart may be involved in a not negligible percentage of the infected patients. Myocarditis-related cardiac dysfunction and potentially life-threatening arrhythmias are the main aftermaths. A few studies showed that myocardial injury in adult patients is often linked with a fatal outcome. Conversely, scientific evidence in children is sparse, although several reports were published with the description of a cardiac involvement in COVID-19 paediatric patients. In these young subjects, a background of surgically treated congenital heart disease seems to be a predisposing factor. This systematic review is aimed at summarizing all COVID-19 cases with a cardiac involvement published in paediatric age and trying to explain the underlying mechanisms responsible for COVID-19-related myocardial damage.

Cite this research | Open access | Vol.: 179 | No. of pages: 1079-1087 | Language: English | Tags: child diseases, child health, COVID-19, Heart diseases
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UNICEF Innocenti's Children and COVID-19 Library is a database collecting research from around the world on COVID-19 and its impacts on children and adolescents.


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COVID-19 & Children: Rapid Research Response

UNICEF Innocenti is mobilizing a rapid research response in line with UNICEF’s global response to the COVID-19 crisis. The initiatives we’ve begun will provide the broad range of evidence needed to inform our work to scale up rapid assessment, develop urgent mitigating strategies in programming and advocacy, and preparation of interventions to respond to the medium and longer-term consequences of the COVID-19 crisis. The research projects cover a rapid review of evidence, education analysis, and social and economic policies.