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Children and COVID-19 Research Library

UNDER DEVELOPMENT UNICEF Innocenti's curated library of COVID-19 + Children research

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1 - 15 of 121
COVID on three continents: how local children’s organizations in Africa, Europe and South America are adapting to the coronavirus challenge

AUTHOR(S)
Suzanne Clulow; Nikoleta Dimitrouka; Iván Zamora Zapata

Published: November 2020   Journal: Journal of Children's Services

The purpose of this paper is to share anecdotally how the pandemic is affecting children, families and some of the frontline local services that support them across three continents.Three members of family for every child across three continents detail some of the day-to-day challenges they are facing in their work with children and families as a result of the coronavirus pandemic.

COVID-19 and multisystem inflammatory syndrome in children and adolescents

AUTHOR(S)
Li Jiang; Kun Tang; Mike Levin (et al.)

Published: November 2020   Journal: The Lancet Infectious Diseases
As severe acute respiratory syndrome coronavirus continues to spread worldwide, there have been increasing reports from Europe, North America, Asia, and Latin America describing children and adolescents with COVID-19-associated multisystem inflammatory conditions. However, the association between multisystem inflammatory syndrome in children and COVID-19 is still unknown. This article reviews the epidemiology, causes, clinical features, and current treatment protocols for multisystem inflammatory syndrome in children and adolescents associated with COVID-19. It also discusses the possible underlying pathophysiological mechanisms for COVID-19-induced inflammatory processes, which can lead to organ damage in paediatric patients who are severely ill. These insights provide evidence for the need to develop a clear case definition and treatment protocol for this new condition and also shed light on future therapeutic interventions and the potential for vaccine development.
Cite this research | Open access | Vol.: 20 | Issue: 11 | No. of pages: 276-288 | Language: English | Topics: Health | Tags: adolescent health, child health, respiratory diseases, COVID-19
Leveraging the COVID-19 response to end preventable child deaths from pneumonia

AUTHOR(S)
Henrietta H. Fore; Tedros Adhanom Ghebreyesu; Kevin Watkins (et al.)

Published: November 2020   Journal: The Lancet
COVID-19 has claimed more than 1 million lives so far in 2020, but other infectious diseases have caused pneumonia-related mortality for decades. Although most children have less illness related to COVID-19 than adults, the potential secondary impacts of the pandemic could cause a reversal in progress in child survival.  Review of routine health information and programme data across several countries indicate that since the onset of the pandemic there have been reductions in the numbers of children who attend outpatient services and who receive correct diagnosis and treatment of illnesses and immunisation services. On World Pneumonia Day, on Nov 12, 2020, it is time to take stock of the key actions the global health community should be taking to support country efforts to strengthen primary health care and health information systems to accelerate progress in preventing child pneumonia infections and deaths.
Where to make a difference: research and the social determinants in pediatrics and child health in the COVID-19 era

AUTHOR(S)
Peter Lachman

Published: October 2020   Journal: Paediatric Research
In 2005, Michael Marmot introduced the concept of the Social Determinants of Health (SDH) in which he proposed what was in plain sight, i.e., that health outcomes are determined by “the conditions in which people are born, grow, live, work and age”. For children, these social determinants influence life opportunities, disease profiles, health outcomes, and life expectancy. Since the initial paper, there has been little progress in addressing the social determinants of health. In a review in 2010, Marmot concluded that social and economic status determines the health outcomes, and the lower the socioeconomic status the worse the outcome. Now, in the midst of a pandemic, the importance of considering the SDH in pediatric research has been highlighted once more by SARS‑CoV-2. In societies affected by the virus, those who suffer inequity and who are negatively influenced by the SDH have been most severely affected. This paper covers the key areas that require attention as we move to the post COVID era.

Age-structured model for COVID-19: Effectiveness of social distancing and contact reduction in Kenya

AUTHOR(S)
Mark Kimathi; Samuel Mwalili; Viona Ojiambo (et al.)

Published: October 2020   Journal: Infectious Disease Modelling
Coronavirus disease 2019 is caused by severe acute respiratory syndrome coronavirus 2. Kenya reported its first case on March 13, 2020 and by March 16, 2020 she instituted physical distancing strategies to reduce transmission and flatten the epidemic curve. An age-structured compartmental model was developed to assess the impact of the strategies on COVID-19 severity and burden. Contacts between different ages are incorporated via contact matrices. Simulation results show that 45% reduction in contacts for 60-days period resulted to 11.5–13% reduction of infections severity and deaths, while for the 190-days period yielded 18.8–22.7% reduction. The peak of infections in the 60-days mitigation was higher and happened about 2 months after the relaxation of mitigation as compared to that of the 190-days mitigation, which happened a month after mitigations were relaxed. Low numbers of cases in children under 15 years was attributed to high number of asymptomatic cases. High numbers of cases are reported in the 15–29 years and 30–59 years age bands. Two mitigation periods, considered in the study, resulted to reductions in severe and critical cases, attack rates, hospital and ICU bed demands, as well as deaths, with the 190-days period giving higher reductions.
Multisystem inflammatory syndrome associated with COVID-19 in children in Pakistan

AUTHOR(S)
Masood Sadiq; Omeir Ali Aziz; Uzma Kazmi (et al.)

Published: October 2020   Journal: The Lancet Child & Adolescent Health
The knowledge of COVID-19 is evolving with new aspects of the disease continuing to emerge. Children and adolescents younger than 20 years of age constitute 10·6% of the total reported confirmed cases of COVID-19 in Pakistan as of July 8, 2020, with a mortality of 0·3% for those aged 10 years or younger and 0·5% for those aged 11–20 years. Multisystem inflammatory syndrome in children (MIS-C), also known as paediatric inflammatory multisystem syndrome temporally associated with severe acute respiratory syndrome coronavirus 2 (PIMS-TS) is being reported primarily from Europe and the USA. Many of these children meet the criteria for complete or incomplete Kawasaki disease, but different clinical presentations of this inflammatory disorder are being reported. The ethnic origin of reported cases show that Black, Hispanic, and Asian children might be disproportionally affected. Similarly, unlike Kawasaki disease, these cases have occurred in older children and adolescents.
Multisystem inflammatory syndrome in children in South Africa

AUTHOR(S)
Kate Webb; Deepthi Raju Abraham; Ayodele Faleye (et al.)

Published: October 2020   Journal: The Lancet Child & Adolescent Health
There are reports of a multisystem inflammatory syndrome in children associated with COVID-19 known as MIS-C or paediatric inflammatory multisystem syndrome temporally associated with severe acute respiratory syndrome coronavirus 2 (PIMS-TS).  The definition of MIS-C issued by WHO includes clinical and laboratory features, with evidence of COVID-19, or likely contact with a person who has or has had COVID-19. South Africa has the most reported COVID-19 cases in Africa, with the Western Cape Province acting as the initial epicentre with a total of 93.414 people with confirmed COVID-19 by July 31, 2020, of whom 2910 were younger than 15 years old.
Cite this research | Open access | Vol.: 4 | Issue: 10 | Language: English | Topics: Health | Tags: child health, respiratory diseases, infectious disease, COVID-19 | Countries: South Africa
The impact of school closures and lockdown on mental health in young people

AUTHOR(S)
Ellen Townsend

Published: October 2020   Journal: Child and Adolescent Mental Health
The COVID‐19 pandemic lockdown response has had a disproportionate and damaging effect on the lives, mental health and well‐being of young people globally. They have been neglected in policy‐making and their needs have been subjugated to those of adults which contravenes the UN Convention on the Rights of the Child. This commentary argues that the needs and rights of young people must come first to protect their health, mental health and futures.
Feasibility and effectiveness of teleconsultation in children with epilepsy amidst the ongoing COVID-19 pandemic in a resource-limited country

AUTHOR(S)
Prateek Kumar Panda; Lesa Dawman; Pragnya Panda (et al.)

Published: October 2020   Journal: Seizure
The ongoing COVID-19 pandemic and the lockdown measures employed by the government have forced neurologists across the world to look upon telemedicine as the only feasible and practical option to continue providing health care towards children with epilepsy in home isolation. Children with epilepsy are challenging for teleconsultation as direct information from the patient is missing, regarding seizures and adverse effects, especially behavioral and psychological side effects.
Cite this research | Open access | Vol.: 81 | No. of pages: 29-35 | Language: English | Topics: Health | Tags: child care services, child health, COVID-19 response, lockdown | Countries: India
The prevalence of behavioral problems among school-aged children in home quarantine during the COVID-19 pandemic in China

AUTHOR(S)
Qi Liu; Xinyan Xie; Qi Xue (et al.)

Published: October 2020   Journal: Journal of Affective Disorders

To prevent spreading of the COVID-19 infection, many countries have implemented a nationwide school closure. This study aimed to assess the prevalence of behavioral problems in school-aged children during home confinement.  An internet-based survey involving 1264 children (grades 2-6) and their parents from two primary schools between February 25 and March 8, 2020 was conducted in Hubei province, China. Behavioral problems were evaluated using the Strengths and Difficulties Questionnaire (SDQ).

Rapid-cycle community assessment of health-related social needs of children and families during COVID-19

AUTHOR(S)
Kristin N. Ray; Anna K. Ettinger; Namita Dwarakanath (et al.)

Published: October 2020   Journal: Academic Pediatrics
Over half of families with children reported unmet health or social service needs during the first month of a county-wide COVID-19 stay-at-home order. Unmet needs varied with race, ethnicity, and income and with duration of the stay-at-home order. This study aims to identify unmet health and social resource needs during a county-wide COVID-19 stay-at-home order and phased re-opening in the US.
How societal responses to COVID-19 could contribute to child neglect

AUTHOR(S)
A. Bérubé; M.-E. Clément; V. Lafantaisie (et al.)

Published: October 2020   Journal: Child Abuse & Neglect
The ecosystemic approach to children’s needs demands a cohesive response from societies, communities, and families. During the COVID-19 pandemic, the choices societies made to protect their community members from the virus could have created contexts of child neglect. With the closure of services and institutions, societies were no longer available to help meet the needs of children. The purpose of this study is to examine parents’ reports on the response their children received to their needs during the COVID-19 crisis. During the period of the spring 2020 lockdown, 414 parents in the province of Quebec, Canada, completed an online questionnaire about the impact of the crisis on the response their children received to their needs.
Risk factors for re‐detectable positivity in recovered COVID‐19 children

AUTHOR(S)
Denggao Peng; Jing Zhang; Yiling Ji (et al.)

Published: October 2020   Journal: Pediatric Pulmonology

This paper aims to identify the risk factors for redetectable positivity, and to provide a basis for prevention and control of coronavirus disease‐2019 (COVID‐19) in children. A retrospective study was performed on all pediatric patients diagnosed with COVID‐19. Redetectable positivity was defined as the positive result of real‐time reverse transcriptase polymerase chain reaction for severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) after symptom resolution and discharge. Children were defined as being less than 18 years old.

Cite this research | Open access | Vol.: 55 | Issue: 12 | No. of pages: 3602-3609 | Language: English | Topics: Health | Tags: child health, disease control, disease prevention, COVID-19
Helping siblings of children with behavioral health disorders weather the COVID‐19 storm

AUTHOR(S)
Wendy Plante

Published: October 2020   Journal: The Brown University Child and Adolescent Behavior Letter
As schools and outpatient clinics shut their doors in the spring of 2020 in response to the COVID‐19 pandemic, children with developmental disabilities were being taught at home, with their parents helping to facilitate their education and many of their special services, sometimes with professionals on the other end of a screen and sometimes not. While it is too soon to know from empirical research how these circumstances have affected typically developing, healthy siblings, we can use the existing research on sibling needs to help parents, schools, medical and behavioral providers, and community supports to predict impact on siblings and put supports into place.
Testing our children when the world shuts down: analyzing recommendations for adapted tele-assessment during COVID-19

AUTHOR(S)
Shelley Kathleen Krach; Tracy L. Paskiewicz; Malaya M. Monk

Published: October 2020   Journal: Journal of Psychoeducational Assessment
In 2017, the National Association of School Psychologists described tele-assessment as the least researched area of telehealth. This became problematic in 2020 when COVID-19 curtailed the administration of face-to-face assessments. Publishers began to offer computer-adapted tele-assessment methods for tests that had only previously been administered in person. Recommendations for adapted tele-assessment practice had to be developed with little empirical data. The current study analyzed recommendations from entities including professional organizations, test publishers, and governmental offices.
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UNICEF Innocenti's Children and COVID-19 Library is a database collecting research from around the world on COVID-19 and its impacts on children and adolescents.

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COVID-19 & Children: Rapid Research Response

UNICEF Innocenti is mobilizing a rapid research response in line with UNICEF’s global response to the COVID-19 crisis. The initiatives we’ve begun will provide the broad range of evidence needed to inform our work to scale up rapid assessment, develop urgent mitigating strategies in programming and advocacy, and preparation of interventions to respond to the medium and longer-term consequences of the COVID-19 crisis. The research projects cover a rapid review of evidence, education analysis, and social and economic policies.