Children and COVID-19 Research Library

In China, there have been more than 1200 paediatric cases. Most paediatric patients acquire the infection through household contact with infected adults. The disease in children is usually self-limiting and most infected children will recover uneventfully within 7–10 days. Other than symptoms of the respiratory tract, many children may present with gastrointestinal symptoms. Older children are more likely to have asymptomatic infection. Although deaths related to SARS-CoV-2 are rarely reported in the paediatric age group, young children and those with underlying medical conditions are more likely to develop severe illness. Only a small fraction of neonates born to infected mother would acquire the virus by vertical transmission. Because a large proportion of children and adolescents may have asymptomatic or mildly symptomatic infection, children are likely to play an important role in community transmission of this infection. Screening of children who have a definitive contact history will facilitate early diagnosis and isolation of all infected children. This review summarises the lessons learned in China with regard to the current understanding of SARS-CoV-2 infection in the paediatric population.

Preterm birth is the leading cause of child mortality globally, with many survivors experiencing long-term adverse consequences. Preliminary evidence suggests that numbers of preterm births greatly reduced following implementation of policy measures aimed at mitigating the effects of the COVID-19 pandemic. This study examines the impact of the COVID-19 mitigation measures implemented in the Netherlands on the incidence of preterm birth through a national quasi-experimental difference-in-regression-discontinuity approach.

There is a high risk that the COVID-19 pandemic may reverse decades-long progress on reducing child mortality and affect the number of stillbirths. This new release of the first-ever joint stillbirth estimates by the United Nations Inter-agency Group for Child Mortality Estimation (UN IGME) presents the number of babies that are stillborn every year due to pregnancy and birth-related complications, the absence of health workers and basic services. The issue has become an essential part of global child survival initiatives. UNICEF calls on international organizations, governments and partners for increased and strong political will, sound policies and targeted investment along the continuum of care for every mother and child.

The COVID-19 global pandemic is expected to result in 8.3-38.6% additional maternal deaths in many low-income countries. The objective of this paper was to determine the initial impact of COVID-19 pandemic on reproductive, maternal, newborn, child and adolescent health (RMNCAH) services in Kenya.

There have been dramatic reductions in child and youth mortality over the last 29 years. Globally, under-five mortality has dropped by 59% since 1990—from 93 deaths per 1,000 live births then to 38 deaths in 2019. Initial evidence suggests that the impact of COVID-19 on direct mortality for children and youth may be small, but indirect effects can be severe. Many life-saving services have already been disrupted by COVID-19. 

Our analysis of COVID-19 in children until the end of May 2020 indicated mortality was rare and lower than from influenza, for which children already have a vaccine. We feared and wrote that over time the severity of the virus in children might increase. We published this in May 20201 and now examine childhood mortality from COVID-19 over time and compared with other causes in seven countries: USA, United Kingdom, Italy, Germany, Spain, France and Republic of Korea.

While the COVID-19 pandemic will increase mortality due to the virus, it is also likely to increase mortality indirectly. This study estimates the additional maternal and under-5 child deaths resulting from the potential disruption of health systems and decreased access to food. Estimates show that if routine health care is disrupted and access to food is decreased (as a result of unavoidable shocks, health system collapse, or intentional choices made in responding to the pandemic), the increase in child and maternal deaths will be substantial.