Children and COVID-19 Research Library

The aims of this research were to review patients visiting the paediatric emergency department over a 6-month period 1 year before and during the pandemic, to review paediatric emergency department referral ratios and to determine whether there were any significant decreases in mortality and morbidity. All patients from the ages of 0 to 18 years visiting the University of Health Sciences, Ankara Research and Training Hospital, paediatric emergency service from April-October 2019 to April-October 2020 with no missing information in their records were involved in this retrospective cross-sectional study.

Ethiopia has made remarkable progress in reducing childhood and neonatal mortality in the last two decades. However, with the spread of the COVID-19 pandemic in Ethiopia, disruptions in routine health care pose a significant risk in reversing the gains made in neonatal mortality reduction. Using the World Health Organization’s health systems building blocks framework we examined the mechanisms by which the pandemic may impact neonatal health.

Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is associated with thrombotic complications in adults, but the incidence of COVID-19 related thrombosis in children and adolescents is unclear. Most children with acute COVID-19 have mild disease, but coagulopathy has been associated with multisystem inflammatory syndrome in children (MIS-C), a post-infectious complication. This study conducted a multicenter retrospective cohort research to determine the incidence of thrombosis in children hospitalized with COVID-19 or MIS-C and to evaluate associated risk factors.

The incidence of COVID-19 is still rapidly increasing, but little is known about the prevalence and characteristics of fatal cases in children in Indonesia. This study aims to describe the characteristics of pediatric COVID-19 cases with fatal outcomes in Indonesia's tertiary referral hospital. This is a cross-sectional study with data collected from the medical records of COVID-19 patients admitted to Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia, from March to October 2020.

The coronavirus disease (COVID-19) has spread worldwide with an increasing number of patients, including pregnant women and neonates. This study aims to evaluate morbidity and mortality in the COVID-19 era compared to the preceding year in the Neonatal Intensive Care Unit (NICU) at Tamale Teaching Hospital, Ghana. This is a cross-sectional study carried out on neonates admitted to NICU between March 1st to August 31st, 2019 (pre-COVID-19 era) and March 1st to August 31st, 2020 (COVID-19 era). Multivariate logistic regression was performed to identify predictors of mortality for both periods.

The increase in malnutrition arising due to the coronavirus pandemic is expected to cause nearly 170,000 additional child deaths in the next two years. Please, read that again, and understand that we are in the middle of a crisis within a crisis. This pandemic has created a fatal cycle: malnourished people are at a higher risk of death or hospitalisation from COVID-19, and the lockdown measures necessary to tackle the virus make it more difficult for people to access healthcare facilities and proper food, thus pushing them closer to malnutrition. Since nutrition underpins all of human flourishing, people in these regions are also under great economic, social, environmental and health strains, and may sink deeper into poverty as a result . Both COVID-19 and malnutrition have intense, long-term impacts, and challenge our ability to reach the Sustainable Development Goals (SDGs). They are emergencies in the short and long term. To avoid this food crisis spiralling out of control, actions to prevent malnutrition must be adopted as an essential part of any COVID-19 response.

In China, there have been more than 1200 paediatric cases. Most paediatric patients acquire the infection through household contact with infected adults. The disease in children is usually self-limiting and most infected children will recover uneventfully within 7–10 days. Other than symptoms of the respiratory tract, many children may present with gastrointestinal symptoms. Older children are more likely to have asymptomatic infection. Although deaths related to SARS-CoV-2 are rarely reported in the paediatric age group, young children and those with underlying medical conditions are more likely to develop severe illness. Only a small fraction of neonates born to infected mother would acquire the virus by vertical transmission. Because a large proportion of children and adolescents may have asymptomatic or mildly symptomatic infection, children are likely to play an important role in community transmission of this infection. Screening of children who have a definitive contact history will facilitate early diagnosis and isolation of all infected children. This review summarises the lessons learned in China with regard to the current understanding of SARS-CoV-2 infection in the paediatric population.

Preterm birth is the leading cause of child mortality globally, with many survivors experiencing long-term adverse consequences. Preliminary evidence suggests that numbers of preterm births greatly reduced following implementation of policy measures aimed at mitigating the effects of the COVID-19 pandemic. This study examines the impact of the COVID-19 mitigation measures implemented in the Netherlands on the incidence of preterm birth through a national quasi-experimental difference-in-regression-discontinuity approach.

There is a high risk that the COVID-19 pandemic may reverse decades-long progress on reducing child mortality and affect the number of stillbirths. This new release of the first-ever joint stillbirth estimates by the United Nations Inter-agency Group for Child Mortality Estimation (UN IGME) presents the number of babies that are stillborn every year due to pregnancy and birth-related complications, the absence of health workers and basic services. The issue has become an essential part of global child survival initiatives. UNICEF calls on international organizations, governments and partners for increased and strong political will, sound policies and targeted investment along the continuum of care for every mother and child.

The COVID-19 global pandemic is expected to result in 8.3-38.6% additional maternal deaths in many low-income countries. The objective of this paper was to determine the initial impact of COVID-19 pandemic on reproductive, maternal, newborn, child and adolescent health (RMNCAH) services in Kenya.

There have been dramatic reductions in child and youth mortality over the last 29 years. Globally, under-five mortality has dropped by 59% since 1990—from 93 deaths per 1,000 live births then to 38 deaths in 2019. Initial evidence suggests that the impact of COVID-19 on direct mortality for children and youth may be small, but indirect effects can be severe. Many life-saving services have already been disrupted by COVID-19. 

Our analysis of COVID-19 in children until the end of May 2020 indicated mortality was rare and lower than from influenza, for which children already have a vaccine. We feared and wrote that over time the severity of the virus in children might increase. We published this in May 20201 and now examine childhood mortality from COVID-19 over time and compared with other causes in seven countries: USA, United Kingdom, Italy, Germany, Spain, France and Republic of Korea.