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Children and COVID-19 Research Library

UNDER DEVELOPMENT UNICEF Innocenti's curated library of COVID-19 + Children research

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Journal article

Post-COVID-19 pediatric inflammatory multisystem syndrome: association of ethnicity, key worker and socioeconomic status with risk and severity

AUTHOR(S)
Jonathan Broad; Julia Forman; James Brighouse (et al.)

Published: April 2021 Journal: Archives of Disease in Childhood

Patients from ethnic minority groups and key workers are over-represented among adults hospitalised or dying from COVID-19. In this population based retrospective cohort, we describe the association of ethnicity, socioeconomic and family key worker status with incidence and severity of Paediatric Inflammatory Multisystem Syndrome Temporally associated with SARSCoV-2 (PIMS-TS).

Journal article

COVID-19 symptom surveillance in immunocompromised children and young people in the UK: a prospective observational cohort study

AUTHOR(S)
Meera Shaunak; Ravin Patel; Corine Driessens (et al.)

Published: March 2021 Journal: BMJ Open

This prospective observational cohort study aims to describe the frequency of symptoms compatible with SARS-CoV-2 infection in immunocompromised children and young people in the UK during the SARS-CoV-2 pandemic. To describe patient/ parent anxiety regarding SARS-CoV-2 infection in this cohort.

Journal article

Clustering and longitudinal change in SARS-CoV-2 seroprevalence in school children in the canton of Zurich, Switzerland: prospective cohort study of 55 schools

AUTHOR(S)
Agne Ulyte; Thomas Radtke; Irene A. Abela

Published: March 2021 Journal: BMJ

This prospective cohort study aims to examine longitudinal changes in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence and to determine the clustering of children who were seropositive within school classes in the canton of Zurich, Switzerland from June to November 2020.

Journal article

Association between living with children and outcomes from covid-19: OpenSAFELY cohort study of 12 million adults in England

AUTHOR(S)
Harriet Forbes; Caroline E. Morton; Seb Bacon (et al.)

Published: March 2021

This population based cohort study, on behalf of NHS England, aimed to investigate whether risk of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and outcomes of coronavirus disease 2019 (covid-19) differed between adults living with and without children during the first two waves of the UK pandemic.

Journal article

Increased risk of rhinovirus infection in children during the coronavirus disease‐19 pandemic

AUTHOR(S)
Emi Takashita; Chiharu Kawakami ; Tomoko Momoki (et al.)

Published: March 2021 Journal: Influenza and Other Respiratory Viruses

Coronavirus disease (COVID‐19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), was first detected in Japan in January 2020 and has spread throughout the country. Previous studies have reported that viral interference among influenza virus, rhinovirus, and other respiratory viruses can affect viral infections at the host and population level. To investigate the impact of COVID‐19 on influenza and other respiratory virus infections, this study analyzed clinical specimens collected from 2244 patients in Japan with respiratory diseases between January 2018 and September 2020.

Journal article

Model-based projections for COVID-19 outbreak size and student-days lost to closure in Ontario childcare centres and primary schools

AUTHOR(S)
Brendon Phillips; Dillon T. Browne; Madhur Anand (et al.)

Published: March 2021 Journal: Scientific Reports volume

There is a pressing need for evidence-based scrutiny of plans to re-open childcare centres during the COVID-19 pandemic. This study developed an agent-based model of SARS-CoV-2 transmission within a childcare centre and households. Scenarios varied the student-to-educator ratio (15:2, 8:2, 7:3), family clustering (siblings together versus random assignment) and time spent in class.

Journal article

Caring for caregivers: the impact of the COVID-19 pandemic on those responsible for children and adolescents with type 1 diabetes

AUTHOR(S)
Janine Alessi; Giovana Berger de Oliveira; Gabriela Feiden (et al.)

Published: March 2021 Journal: Scientific Reports volume

This study aimed to assess the psychological impact of the COVID-19 pandemic on guardians of children and adolescents with type 1 diabetes. An online survey was performed to assess the prevalence of pandemic-related emotional burden, mental health disorders and diabetes-specifc emotional burden related to diabetes care during the COVID-19 pandemic. Caregivers of children and adolescents with diabetes under the age of 18 and caregivers of youth without diabetes for the non-diabetes group were invited to participate.

Cite this research | No. of pages: 10 | Language: English | Topics: Health | Tags: disease control, care work, COVID-19 response, diabetes

Journal article

COVID-19 management in pediatrics

AUTHOR(S)
Magalie L. Alcindor; FitzGerald Alcindor; Kristy E. Richard

Published: March 2021 Journal: The Journal for Nurse Practitioners

Coronavirus disease 2019 (COVID-19) is a deadly global pandemic, with scientific efforts improving our understanding of this novel coronavirus. No proven disease-specific therapies exist, although 2 vaccines have been recently approved by the United States Food and Drug Administration under emergency use authori-zation, and several others are in development or phase III clinical trial testing. COVID-19 presents in greater severity in the medically fragile, obese, elderly, and socially disadvantaged, and children in general are less affected. All children are at risk, but those with comorbidities and neonates are more susceptible. The multisystem inflammatory syndrome is a severe version which can present in any child with a recent COVID-19 infection. The face of the pandemic has been changing in the last few months, with recent increasing cases,virus mutations, and onset of vaccination. This article provides COVID-19 management for children and adolescents and implications for nursing and advanced practice providers.

Journal article

Global effect of the COVID-19 pandemic on paediatric cancer care: a cross-sectional study

AUTHOR(S)
Dylan Graetz; Asya Agulnik; Radhikesh Ranadive (et al.)

Published: March 2021 Journal: The Lancet Child & Adolescent Health

Although mortality due to COVID-19 has been reportedly low among children with cancer, changes in health-care services due to the pandemic have affected cancer care delivery. This study aimed to assess the effect of the COVID-19 pandemic on childhood cancer care worldwide.

Journal article

Sharing a household with children and risk of COVID-19: a study of over 300 000 adults living in healthcare worker households in Scotland

AUTHOR(S)
Rachael Wood; Emma Thomson; Robert Galbraith (et al.)

Published: February 2021 Journal: Archives of Disease in Childhood

Children are relatively protected from COVID-19, due to a range of potential mechanisms. This cohort study based on linked administrative data in Scotland investigated if contact with children also affords adults a degree of protection from COVID-19.

Journal article

Management of malaria in children younger than 5 years old during Coronavirus disease 2019 pandemic in Sierra Leone: a lesson learned?

AUTHOR(S)
Danilo Buonsenso; Francesco Iodice; Bianca Cinicola (et al.)

Published: February 2021 Journal: Frontiers in Pediatrics

Growing evidences are showing the potential indirect effects of the Coronavirus Disease 2019 (COVID-19) on the health systems of low-resource settings, where diseases such as Tuberculosis, Human Immunodeficiency Virus (HIV) and Malaria represent major killers. Therefore, this study performed a retrospective study aimed to evaluate the impact of COVID-19 on Malaria programs in a peripheral region of Sierra Leone, previously involved by the Ebola outbreak in 2015, when malaria care have been impaired since local health systems were overwhelmed by Ebola cases. During COVID-19 in Sierra Leone, it has not been noticed a significant drop in malaria diagnosis in children, suggesting that a proactive approach in the management of malaria in endemic countries during COVID-19 may have had a positive impact. A comprehensive approach that include also educational activities to sensitize the local population, was useful to guarantee successful malaria diagnosis and treatment, and prevents excess of malaria deaths due to potential disruption of the local health systems related to the SARS-CoV-2 pandemic.

Evidence Synthesis and other Reviews

COVID‐19 under 19: a meta‐analysis

AUTHOR(S)
Nagham Toba; Shreya Gupta; Abdulrahman Y. Ali (et al.)

Published: February 2021 Journal: Pediatric Pulmonology

The coronavirus disease 2019 (COVID‐19) pandemic continues to cause global havoc posing uncertainty to educational institutions worldwide. Understanding the clinical characteristics of COVID‐19 in children is important because of the potential impact on clinical management and public health decisions. A meta‐analysis was conducted for pediatric COVID‐19 studies using PubMed and Scopus. It reviewed demographics, co‐morbidities, clinical manifestations, laboratory investigations, radiological investigations, treatment, and outcomes. The 95% confidence interval (CI) was utilized.

Journal article

Impact of the COVID-19 pandemic on children with psoriasis

AUTHOR(S)
Q. Beytout; J. Pepiot; A. Maruani (et al.)

Published: February 2021 Journal: Annales de Dermatologie et de Vénéréologie

Children with psoriasis may have been directly impacted by the COVID-19 pandemic and their illness may also have affected their ability to follow preventive measures. To investigate the impact of the COVID-19 pandemic on children with psoriasis.

Journal article

Demographic, clinical and laboratory features of COVID‐19 in children: the role of mean platelet volume in predicting the hospitalization and severity

AUTHOR(S)
Gizem Guner Ozenen; Zumrut Sahbudak Bal; Zuhal Umit (et al.)

Published: February 2021 Journal: Journal of Medical Virology

There have been limited number of studies on COVID‐19 in children. This study aimed to investigate the demographic, clinical, and laboratory features of COVID‐19 and to identify the role of mean platelet volume (MPV) in predicting the prognosis in children. A single‐center retrospective study, including 251 confirmed and 65 suspected COVID‐19 cases, was conducted between March 11, 2020, and December 11, 2020.

Journal article

The critical need for pooled data on COVID-19 in African children: an AFREhealth call for action through multi-country research collaboration

AUTHOR(S)
Nadia A. Sam-Agudu; Helena Rabie; Michel Tshiasuma Pipo (et al.)

Published: February 2021

Globally, there are prevailing knowledge gaps in the epidemiology, clinical manifestations, and outcomes of SARS-CoV-2 infection among children and adolescents; however, these gaps are especially wide in African countries. The availability of robust age-disaggregated data is a critical first step in improving knowledge on disease burden and manifestations of COVID-19 among children. Furthermore, it is essential to improve understanding of SARS-CoV-2 interactions with comorbidities and co-infections such as HIV, tuberculosis, malaria, sickle cell disease and malnutrition, which are highly prevalent among children in sub-Saharan Africa.

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UNICEF Innocenti's Children and COVID-19 Library is a database collecting research from around the world on COVID-19 and its impacts on children and adolescents.

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