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Children and COVID-19 Research Library

UNDER DEVELOPMENT UNICEF Innocenti's curated library of COVID-19 + Children research

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1 - 15 of 165
Clinical characteristics and risk factors for death among hospitalised children and adolescents with COVID-19 in Brazil: an analysis of a nationwide database

Eduardo A. Oliveira; Enrico A. Colosimo; Ana Cristina Simões e Silva (et al.)

Published: June 2021   Journal: The Lancet Child & Adolescent Health
COVID-19 is usually less severe and has lower case fatality in children than in adults. This study aimed to characterise the clinical features of children and adolescents hospitalised with laboratory-confirmed SARS-CoV-2 infection and to evaluate the risk factors for COVID-19-related death in this population. It did an analysis of all patients younger than 20 years who had quantitative RT-PCR-confirmed COVID-19 and were registered in the Influenza Epidemiological Surveillance Information System (SIVEP-Gripe, a nationwide surveillance database of patients admitted to hospital with severe acute respiratory disease in Brazil), between Feb 16, 2020, and Jan 9, 2021. The primary outcome was time to recovery (discharge) or in-hospital death, evaluated by competing risks analysis using the cumulative incidence function.
Cite this research | Open access | No. of pages: 10 | Language: English | Topics: Health | Tags: child health, COVID-19, disease transmission, hospitalization | Countries: Brazil
Children’s pictures of COVID-19 and measures to mitigate its spread: An international qualitative study

Lucy Bray; Lucy Blake; Jo Protheroe (et al.)

Published: June 2021   Journal: Health Education Journal

This study aims to gain insight into children’s health-related knowledge and understanding of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) and COVID-19, and measures adopted to mitigate transmission. A child-centred qualitative creative element embedded in an online mixed-methods survey of children aged 7–12 years. Children participated in the study in six countries – the UK, Australia, Sweden, Brazil, Spain and Canada.

Characteristics of children with confirmed SARS-CoV-2 infection in Indonesia

Amin Soebandrio; Tina Kusumaningrum; Frilasita A. Yudhaputri (et al.)

Published: June 2021   Journal: Journal of Clinical Virology Plus

COVID‐19 in children poses a significant challenge due to the atypical/asymptomatic presentations. The study is aimed to help understand clinical characteristics in Indonesian children for better management and control of transmission. Clinical characteristics of children with confirmed COVID‐19 were retrospectively analysed from the database dating from March to November 2020.

Cite this research | Open access | No. of pages: 14 | Language: English | Topics: Health | Tags: child health, COVID-19, disease control, disease transmission | Countries: Indonesia
Causes of anxiety among teachers giving face-to-face lessons after the reopening of schools during the COVID-19 pandemic: a cross-sectional study

Nobuyuki Wakui; Shinichiro Abe; Shunsuke Shirozu (et al.)

Published: June 2021   Journal: BMC Public Health
Coronavirus infections are spreading rapidly worldwide, and primary and middle schools are closed in many countries. After the state of emergency was lifted in Japan, schools have reopened, and teachers are conducting face-to-face classes while maintaining safety precautions. This study aimed to assess the factors contributing to infection-related anxiety and educational anxiety among teachers conducting face-to-face classes during the COVID-19 pandemic after schools reopened.
Good knowledge but poor practice toward COVID-19 among Indonesian youth

Ahmad Fuady; Levina Chandra Khoe; Tiara Berliana Azzahra (et al.)

Published: May 2021   Journal: Asia Pacific Journal of Public Health
COVID-19 cases have been increasing among young people as they are often considered to have low compliance with COVID-19 preventive measures. Given that challenge, there have been limited studies exploring this issue. Through a nationwide online survey, this study assessed knowledge, attitudes, and practice toward COVID-19 among Indonesian youth and potential interventions to improve their behavior.
The impact of personal protective equipment and social distancing on communication and relation between nurses, caregivers and children: a descriptive qualitative study in a maternal and child health hospital

Giada Ferrari; Raffaella Dobrina; Sara Buchini (et al.)

Published: May 2021   Journal: Journal of Clinical Nursing

The main objective was to explore the impact of personal protective equipment and social distancing on nurses, caregivers and children's communication and relationship in a maternal and child health hospital. The spread of COVID-19 pandemic made it necessary to apply infection prevention and control measures, including interpersonal distancing and the use of personal protective equipment. These measures may impact communication and relationship between nurses, patients and caregivers especially in a complex environment, such as a paediatric setting.

COVID-19 in children and the effect of schools reopening on potential transmission to household members

Shirley Shapiro Ben David; Daniella Cohen; Diana Tasher (et al.)

Published: May 2021   Journal: Acta Paediatrica
The effect of reopening schools on children's contribution to SARS-CoV-2 transmission, especially within households, remains controversial. This study describes the clinical presentation of a large ambulatory COVID-19 pediatric cohort and evaluates the role of children in household transmission prior to and following school reopening.
Understanding COVID-19: are children the key?

Suz Warner; Alex Richter; Zania Stamataki (et al.)

Published: May 2021   Journal: BMJ Paediatrics Open
The devastating impact of the COVID-19 pandemic on global health and economic stability is immeasurable. The situation is dynamic and fast-evolving, with the world facing new variants of concern which may have immune escape potential. With threatened treatment and preventative strategies at stake, and the prospect of reinfection prolonging the pandemic, it is more crucial than ever to understand the pathogenesis of SARS-CoV-2 infection, which intriguingly disproportionately affects adults and the elderly. Children infected with SARS-CoV-2 remain largely asymptomatic or undergo a transient mild illness. Understanding why children have a milder phenotype and a significant survival advantage may help identify modifiable risk factors in adults.
Knowledge and practice to prevent COVID-19 and its associated factors among pregnant women in Debre Tabor Town Northwest Ethiopia, a community-based cross-sectional study

Alemu Degu Ayele; Gedefaye Nibret Mihretie; Habtamu Gebrehana Belay (et al.)

Published: May 2021   Journal: BMC Pregnancy and Childbirth
Coronavirus disease is now a global concern with the non-availability of antiviral treatment and attacks all groups of the population. Hence, applying preventive measures is the most critical intervention to control the infection. Pregnant women are particularly susceptible to respiratory pathogens because of their immunosuppressive state and physiological adaptive change during pregnancy. Therefore, this study was aimed to assess knowledge and practice to prevent coronavirus disease and its associated factors among pregnant women in Debre Tabor Town.
Prevalence and contributory factors of anxiety and depression among pregnant women in the post-pandemic era of COVID-19 in Shenzhen, China

Fei Wu; Wei Lin; Peiyi Liu (et al.)

Published: May 2021   Journal: Journal of Affective Disorders

Pregnant women are emotionally vulnerable and have suffered great psychological impacts. Following the coronavirus disease 2019 (COVID-19) outbreak, a study was undertaken of the prevalence of, and factors contributing to, symptoms of anxiety and depression among pregnant women in Shenzhen, China. A cross-sectional study on pregnant women was conducted from September to December 2020 in Shenzhen, using a random-recruit method. The General Anxiety Disorder (GAD-7) and Patient Health Questionnaire (PHQ-9) surveys were used to evaluate symptoms of anxiety and depression. A multivariate logistic regression model was developed to explore factors potentially associated with symptoms of anxiety and depression during pregnancy.

Neonatal outcomes of pregnant women with COVID-19 in a developing country setup

Manas Kumar Nayak; Santosh Kumar Panda; Subhra Snigdha Panda (et al.)

Published: May 2021   Journal: Pediatrics and Neonatology

Current evidence on vertical transmission of severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) and neonatal outcome among exposed newborns is emerging and posing a challenge for preventive interventions. Perinatal transmission to the neonates especially during breastfeeding and rooming in is also relatively unknown. This prospective observational study was conducted in Kalinga Institute of Medical Science (KIMS), Odisha state from 1st May to 20th October 2020. A total of 165 neonates born to SARS-CoV-2 infected mothers were enrolled. Real time polymerase chain reaction (RT PCR) testing was done in first 32 neonates in initial 24 hours of life.

Impact of COVID-19 on pediatric Immunocompromised patients

James A. Connelly; Hey Chong; Adam J. Esbenshade (et al.)

Published: May 2021   Journal: Pediatric Clinics of North America
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has caused critical coronavirus disease (COVID-19) most often in the elderly and individuals with co-morbid medical conditions. Although growing evidence supports the importance of an intact innate immune response at the onset of viral infection, mortality caused by dysregulated immune responses, particularly in adults, has shown a spotlight on the delicate balance of a robust, but coordinated and controlled immune activity against infection.  This complex network of infection, immune response, and inflammation with SARS-CoV-2 has created concerns, questions, and challenges for immunocompromised children beyond fear of death from contracting SARS-CoV-2. This review examines how adaptations by health care systems to reduce SARS-CoV-2 transmission and treat the surge of COVID-19 patients impacted immunocompromised pediatric patients.

Assessing School-based Policy actions for COVID-19: an agent-based analysis of incremental infection risk

Reyhaneh Zafarnejad; Paul M. Griffin

Published: May 2021   Journal: Computers in Biology and Medicine
Many schools and universities have seen a significant increase in the spread of COVID-19. As such, a number of non-pharmaceutical interventions have been proposed including distancing requirements, surveillance testing, and updating ventilation systems. Unfortunately, there is limited guidance for which policy or set of policies are most effective for a specific school system. This study develops a novel approach to model the spread of SARS-CoV-2 quanta in a closed classroom environment that extends traditional transmission models that assume uniform mixing through air recirculation by including the local spread of quanta from a contagious source. In addition, the behavior of students with respect to guideline compliance was modeled through an agent-based simulation.
COVID-19 outbreaks following full reopening of primary and secondary schools in England: Cross-sectional national surveillance, November 2020

Felicity Aiano; Anna A. Mensah; Kelsey McOwat (et al.)

Published: May 2021   Journal: The Lancet Regional Health - Europe
The full reopening of schools in September 2020 was associated with an increase in COVID-19 cases and outbreaks in educational settings across England. Primary and secondary schools reporting an outbreak (≥2 laboratory-confirmed cases within 14 days) to Public Health England (PHE) between 31 August and 18 October 2020 were contacted in November 2020 to complete an online questionnaire.
Staff–pupil SARS-CoV-2 infection pathways in schools in Wales: a population-level linked data approach

Daniel A Thompson; Hoda Abbasizanjani; Richard Fry (et al.)

Published: May 2021   Journal: BMJ Paediatrics Open

Better understanding of the role that children and school staff play in the transmission of SARS-CoV-2 is essential to guide policy development on controlling infection while minimising disruption to children’s education and well-being. This national e-cohort (n=464531) study used anonymised linked data for pupils, staff and associated households linked via educational settings in Wales. It estimated the odds of testing positive for SARS-CoV-2 infection for staff and pupils over the period August– December 2020, dependent on measures of recent exposure to known cases linked to their educational settings.

Cite this research | Vol.: 5 | Issue: 1 | No. of pages: 7 | Language: English | Topics: Education | Tags: child education, COVID-19 response, disease transmission, infectious disease, lockdown, school attendance | Countries: United Kingdom
1 - 15 of 165

UNICEF Innocenti's Children and COVID-19 Library is a database collecting research from around the world on COVID-19 and its impacts on children and adolescents.


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COVID-19 & Children: Rapid Research Response

UNICEF Innocenti is mobilizing a rapid research response in line with UNICEF’s global response to the COVID-19 crisis. The initiatives we’ve begun will provide the broad range of evidence needed to inform our work to scale up rapid assessment, develop urgent mitigating strategies in programming and advocacy, and preparation of interventions to respond to the medium and longer-term consequences of the COVID-19 crisis. The research projects cover a rapid review of evidence, education analysis, and social and economic policies.