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Children and COVID-19 Research Library

UNICEF Innocenti's curated library of COVID-19 + Children research

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1 - 15 of 255
A critical assessment of the potential vertical transmission hypotheses: Implications for research on the early-life infection with COVID-19

AUTHOR(S)
Mengqin Yang; Qiuqin Wang; Yulei Song (et al.)

Published: October 2021   Journal: Placenta
The risk of potential vertical transmission in SARS-CoV-2 infected pregnant women is currently a topic of debate. To explore the correlation between the two, this study searched PubMed, Embase®, and Web of Science for studies on vertical transmission of COVID-19. The quality of the studies was evaluated by the Cochrane risk of bias tool. Detailed information of each included case including methods of delivery, protection measures for mothers and neonates at birth, types of specimens, inspection time, results of testing and feeding patterns was collected to assess the possibility of vertical transmission.
COVID-19 and schools: what is the risk of contagion? Results of a rapid-antigen-test-based screening campaign in Florence, Italy

AUTHOR(S)
Guglielmo Bonaccorsi; Sonia Paoli; Massimiliano Alberto Biamonte (et al.)

Published: October 2021   Journal: International Journal of Infectious Diseases

In the coronavirus disease 2019 era, debate around the risk of contagion in school is intense in Italy. The Department of Welfare and Health of Florence promoted a screening campaign with rapid antigen tests for all students and school personnel. The aim of this study was to assess the circulation of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in the school setting by means of mass screening in every primary and middle school in Florence. All students and school personnel at primary and middle schools in Florence were asked to take part. The campaign started on 16 November 2020 and was completed on 12 February 2021. If a subject had a positive result on rapid antigen testing, a molecular test was performed to confirm the result.

Schooling in the time of COVID-19, a resource pack produced by UNICEF ECARO and WHO Europe
Institution: *UNICEF
Published: October 2021

Schools are essential for children’s learning, health, safety and well-being. But students’ learning suffered a major setback when most educational institutions reduced or cancelled in-person instruction and moved to remote learning and teaching to minimize the spread of COVID-19. Prolonged school closures continue to jeopardise the future of millions of children across the globe. The Europe and Central Asia Region is no exception. Schools should be the first to open and last to close. Getting children back in the classroom remains a priority for UNICEF and WHO Regional Offices, striking a balance between applying public health and social measures and ensuring that children are able to continue learning and socializing to the greatest extent possible. UNICEF and WHO have created several tools and resources to support countries in their back-to-school efforts. This joint UNICEF Regional Office for Europe and Central Asia (UNICEF/ ECARO) and WHO Regional Office for Europe Schooling Resource Pack has an easy-to-find compilation of materials to help parents/caregivers, teachers and students return to school safely.

COVID-19 vaccination in pregnancy and lactation: current research and gaps in understanding

AUTHOR(S)
Lydia L. Shook; Parisa N. Fallah; Jason N. Silberman (et al.)

Published: September 2021   Journal: Frontiers in Cellular Infection
The COVID-19 pandemic has demonstrated the urgent need to develop vaccine strategies optimized for pregnant people and their newborns, as both populations are at risk of developing severe disease. Although not included in COVID-19 vaccine development trials, pregnant people have had access to these vaccines since their initial release in the US and abroad. The rapid development and distribution of novel COVID-19 vaccines to people at risk, including those who are pregnant and lactating, presents an unprecedented opportunity to further our understanding of vaccine-induced immunity in these populations. This review aims to summarize the literature to date on COVID-19 vaccination in pregnancy and lactation and highlight opportunities for investigation that may inform future maternal vaccine development and implementation strategies.
Prevalence and risk factors for SARS-CoV-2 infection in children with and without symptoms seeking care in Managua, Nicaragua: results of a cross-sectional survey

AUTHOR(S)
Jorge A. Huete-Pérez; Kacey C. Ernst; Cristiana Cabezas-Robelo (et al.)

Published: September 2021   Journal: BMJ Open

This study aimed to capture key epidemiological data on SARS-CoV-2 infection in Nicaraguan children (≤18 years) seeking medical care, between 6 October and 16 November 2020. In this cross-sectional study, 418 children were recruited: 319 with symptoms characteristic of COVID-19 and 99 with no symptoms of illness. Children were tested for SARS-CoV-2 RNA using loop-mediated isothermal amplification. A questionnaire was employed to identify symptoms, risk factors, comorbidities and COVID-19 prevention measures. Research was carried out in four hospitals and two clinics in Managua, Nicaragua, where schools and businesses remained open throughout the COVID-19 pandemic.

Cite this research | Open access | Vol.: 11 | Issue: 9 | No. of pages: 11 | Language: English | Topics: Health | Tags: child health, COVID-19, disease control, disease transmission, hospitalization, infectious disease | Countries: Nicaragua
Assessment of a program for SARS-CoV-2 screening and environmental monitoring in an urban public school district

AUTHOR(S)
John Crowe; Andy T. Schnaubelt; Scott SchmidtBonne (et al.)

Published: September 2021   Journal: JAMA Netw Open

Scalable programs for school-based SARS-CoV-2 testing and surveillance are needed to guide in-person learning practices and inform risk assessments in kindergarten through 12th grade settings. To characterize SARS-CoV-2 infections in staff and students in an urban public school setting and evaluate test-based strategies to support ongoing risk assessment and mitigation for kindergarten through 12th grade in-person learning. This pilot quality improvement program engaged 3 schools in Omaha, Nebraska, for weekly saliva polymerase chain reaction testing of staff and students participating in in-person learning over a 5-week period from November 9 to December 11, 2020. Wastewater, air, and surface samples were collected weekly and tested for SARS-CoV-2 RNA to evaluate surrogacy for case detection and interrogate transmission risk of in-building activities.

Global research priorities for COVID-19 in maternal, reproductive and child health: Results of an international survey

AUTHOR(S)
Melanie Etti; Jackeline Alger; Sofía P. Salas (et al.)

Published: September 2021   Journal: Plos One

The World Health Organization’s “Coordinated Global Research Roadmap: 2019 Novel Coronavirus” outlined the need for research that focuses on the impact of COVID-19 on pregnant women and children. More than one year after the first reported case significant knowledge gaps remain, highlighting the need for a coordinated approach. To address this need, the Maternal, Newborn and Child Health Working Group (MNCH WG) of the COVID-19 Clinical Research Coalition conducted an international survey to identify global research priorities for COVID-19 in maternal, reproductive and child health. This project was undertaken using a modified Delphi method. An electronic questionnaire was disseminated to clinicians and researchers in three different languages (English, French and Spanish) via MNCH WG affiliated networks. Respondents were asked to select the five most urgent research priorities among a list of 17 identified by the MNCH

Reasons for SARS-CoV-2 infection in children and their role in the transmission of infection according to age: a case-control study

AUTHOR(S)
Mauro Calvani; Giulia Cantiello; Maria Cavani (et al.)

Published: September 2021   Journal: Italian Journal of Pediatrics

The locations where children get exposed to SARS-CoV-2 infection and their contribution in spreading the infection are still not fully understood. Aim of the article is to verify the most frequent reasons for SARS-CoV-2 infection in children and their role in the secondary transmission of the infection. A case-control study was performed in all SARS-CoV-2 positive children (n = 81) and an equal number of age- and sex- matched controls who were referred to the S. Camillo-Forlanini Pediatric Walk-in Center of Rome. The results of all SARS-CoV-2 nasopharyngeal swabs performed in children aged < 18 years from October 16 to December 19, 2020 were analyzed.

Covid-19 infection in pregnant women in Dubai: a case-control study
Published: September 2021   Journal: BMC Pregnancy and Childbirth

Whilst the impact of Covid-19 infection in pregnant women has been examined, there is a scarcity of data on pregnant women in the Middle East. Thus, the aim of this study was to examine the impact of Covid-19 infection on pregnant women in the United Arab Emirates population. A case-control study was carried out to compare the clinical course and outcome of pregnancy in 79 pregnant women with Covid-19 and 85 non-pregnant women with Covid-19 admitted to Latifa Hospital in Dubai between March and June 2020.

Why did some parents not send their children back to school following school closures during the COVID-19 pandemic: a cross-sectional survey

AUTHOR(S)
Lisa Woodland; Louise E. Smith; Rebecca K. Webster (et al.)

Published: September 2021   Journal: BMJ Paediatrics Open

On 23 March 2020, schools closed to most children in England in response to COVID-19 until September 2020. Schools were kept open to children of key workers and vulnerable children on a voluntary basis. Starting 1 June 2020, children in reception (4–5 years old), year 1 (5–6 years old) and year 6 (10–11 years old) also became eligible to attend school. 1373 parents or guardians of children eligible to attend school completed a cross-sectional survey between 8 and 11 June 2020. This study investigated factors associated with whether children attended school or not.

Effect of knowledge acquisition on gravida’s anxiety during COVID-19

AUTHOR(S)
Ying Huang; Weiwei Bian; Yingting Han

Published: September 2021   Journal: Sexual & Reproductive Healthcare

Pregnant women in China are among those most affected by COVID-19. This article assesses Chinese pregnant women’s COVID-19 and pregnancy knowledge levels, including the modality through which such knowledge was acquired, the degree of difficulty in acquiring the knowledge, the means of confirming the accuracy of the knowledge, and difficulties in seeking help from people who possess relevant medical knowledge. The Mantel-Haenszel chi-square test was used to assess trends in binomial proportions. Multivariable binary logistic regression was performed to identify the association between knowledge acquisition and anxiety among pregnant women.

Short-term outcomes of infants born to mothers with SARS-CoV-2 infection

AUTHOR(S)
Michael A. Moffat; Almaz S. Dessie; Kathryn O’Leary (et al.)

Published: September 2021   Journal: The Journal of Maternal-Fetal & Neonatal Medicine

The rate of transmission of SARS-CoV-2 from mothers to infants in the peri- and post-natal period remains an area of ongoing investigation. This study aims to determine rates of development of clinically significant COVID-19 disease within 1 month among infants born to symptomatic and asymptomatic SARS-CoV-2 positive mothers. This was a single-center, retrospective cohort study of all infants born to SARS-CoV-2 positive mothers who were admitted to the Well Baby Nursery (WBN) at New York University Langone Hospital-Brooklyn from 23 March–23 September 2020. Infants born to asymptomatic mothers were allowed to room-in, while infants born to mothers with symptoms of SARS-CoV-2 were isolated and discharged home to an alternate primary caregiver. A phone follow-up program contacted mothers at 2 weeks and 1 month post discharge to inquire about newborn symptoms, maternal symptoms, personal protective equipment (PPE) usage, and any presentations to care. Medical records were also reviewed for clinic and hospital visits to determine if exposed infants developed any symptoms following discharge.

Breastfeeding during the Covid-19 pandemic

AUTHOR(S)
J. P. Dadhich; Nupur Bidla

Published: September 2021   Journal: Journal of Neonatology
The COVID-19 pandemic has posed a serious challenge to the lactating women to practice optimal infant and young child feeding. Although international and national agencies developed appropriate evidence-based guidelines early in the pandemic, availability of this information to the mothers and their caregivers needs to be enhanced. This becomes important in view of apprehension about the risk of a decline in breastfeeding practices during the pandemic due to various factors. Any decrease in the breastfeeding rates may lead to increased childhood morbidity, mortality, and malnutrition. This article provides a glimpse of available evidence-based guidelines on breastfeeding by Covid-19 positive mothers and attempts by the baby food industry to exploit the situation by promoting their products. The article also deals with infection prevention and control measures to be observed by the mother while caring and breastfeeding her baby and other action required to protect breastfeeding from commercial influence.
Pooling in a pod: a strategy for COVID-19 testing to facilitate a safe return to school

AUTHOR(S)
Ethan M. Berke; Lori M. Newman; Suzanna Jemsby (et al.)

Published: September 2021   Journal: Public Health Reports
The COVID-19 pandemic prompted widespread closures of primary and secondary schools. Routine testing of asymptomatic students and staff members, as part of a comprehensive mitigation program, can help schools open safely. “Pooling in a pod” is a public health surveillance strategy whereby testing cohorts (pods) are based on social relationships and physical proximity. Pooled testing provides a single laboratory test result for the entire pod, rather than a separate result for each person in the pod. During the 2020-2021 school year, an independent preschool–grade 12 school in Washington, DC, used pooling in a pod for weekly on-site point-of-care testing of all staff members and students.
The breastfeeding experiences of COVID-19-positive women: a qualitative study in Turkey

AUTHOR(S)
Özlem Aşcı; Meltem Demirgöz Bal; Ayla Ergin

Published: September 2021   Journal: Japan Journal of Nursing Science

The aim of the study was to determine the breastfeeding experiences of COVID-19-positive women. This was a qualitative study of 14 women diagnosed with COVID-19. One-to-one telephone interviews were conducted and recorded. The data were analyzed thematically.

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UNICEF Innocenti's Children and COVID-19 Library is a database collecting research from around the world on COVID-19 and its impacts on children and adolescents.

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COVID-19 & Children: Rapid Research Response

UNICEF Innocenti is mobilizing a rapid research response in line with UNICEF’s global response to the COVID-19 crisis. The initiatives we’ve begun will provide the broad range of evidence needed to inform our work to scale up rapid assessment, develop urgent mitigating strategies in programming and advocacy, and preparation of interventions to respond to the medium and longer-term consequences of the COVID-19 crisis. The research projects cover a rapid review of evidence, education analysis, and social and economic policies.