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Children and COVID-19 Research Library

UNDER DEVELOPMENT UNICEF Innocenti's curated library of COVID-19 + Children research

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46 - 60 of 161
Demographic, psychological, and experiential correlates of SARS-CoV-2 vaccination intentions in a sample of Canadian families

AUTHOR(S)
Christine L. Lackner; Charles H. Wang

Published: March 2021   Journal: Vaccine: X
The COVID-19 pandemic has been ongoing for close to a year, with second waves occurring presently and many viewing vaccine uptake as the most likely way to curb successive waves and promote herd immunity. Reaching herd immunity status likely necessitates that children, as well as their parents, receive a vaccine targeting SARS-CoV-2. This exploratory study investigated the demographic, experiential, and psychological factors associated with the anticipated likelihood and speed of having children receive a SARS-CoV-2 vaccine in a sample of 455 Canadian families (858 children; parents’ mean age = 38.2 ± 6.82 years).
Prevalence of RT-qPCR-detected SARS-CoV-2 infection at schools: first results from the Austrian School-SARS-CoV-2 prospective cohort study

AUTHOR(S)
Peter Willeit; Robert Krause; Bernd Lamprecht

Published: March 2021   Journal: The Lancet Regional Health - Europe Log inRegister RESEAR
The role of schools in the SARS-CoV-2 pandemic is much debated. We aimed to quantify reliably the prevalence of SARS-CoV-2 infections at schools detected with reverse-transcription quantitative polymerase-chain-reaction (RT-qPCR). This nationwide prospective cohort study monitors a representative sample of pupils (grade 1–8) and teachers at Austrian schools throughout the school year 2020/2021. It repeatedly tested participants for SARS-CoV-2 infection using a gargling solution and RT-qPCR and herein reported on the first two rounds of examinations.
Cite this research | Open access | No. of pages: 9 | Language: English | Topics: Health | Tags: COVID-19, disease transmission, infectious disease, school attendance | Countries: Austria
A cross-sectional and prospective cohort study of the role of schools in the SARS-CoV-2 second wave in Italy

AUTHOR(S)
Sara Gandini; Maurizio Rainisio; Maria Luisa Iannuzzo (et al.)

Published: March 2021   Journal: The Lancet Regional Health - Europe
During COVID-19 pandemic, school closure has been mandated in analogy to its effect against influenza, but it is unclear whether schools are early COVID-19 amplifiers. A cross-sectional and prospective cohort study was performed in Italy during the second COVID-19 wave (from September 30, 2020 until at least February 28, 2021). Databases from the Italian Ministry of Education and the Veneto region systems of SARS-CoV-2 cases notification and of schools’ secondary cases tracing were used to compare SARS-CoV-2 incidence in students/school staff and general population and incidence across age groups. Number of tests, secondary infections by type of index case and ratio cases/ tests per school were estimated using an adjusted multivariable generalized linear regression model. Regional reproduction numbers Rt were estimated from Italian Civil Protection daily incidence data with a method of posterior distribution using a Markov Chain Monte Carlo algorithm.
SARS-CoV-2 prevalence associated to low socioeconomic status and overcrowding in an LMIC megacity: a population-based seroepidemiological survey in Lima, Peru

AUTHOR(S)
Mary F. Reyes-Vega; M.Gabriela Soto-Cabezas; Fany Cardenas (et al.)

Published: March 2021   Journal: EClinicalMedicine
Worldwide, Peru has one of the highest infection fatality rates of COVID-19, and its capital city, Lima, accumulates roughly 50% of diagnosed cases. Despite surveillance efforts to assess the extent of the pandemic, reported cases and deaths only capture a fraction of its impact due to COVID-19′s broad clinical spectrum. This study aimed to estimate the seroprevalence of SARS-CoV-2 in Lima, stratified by age, sex, region, socioeconomic status (SES), overcrowding, and symptoms.
Impact of SARS-CoV-2 on the clinical outcomes and placental pathology of pregnant women and their infants: a systematic review

AUTHOR(S)
Irina Oltean; Jason Tran; Sarah Lawrence (et al.)

Published: March 2021   Journal: Heliyon
Pregnant women are susceptible to viral infections due to physiological changes such as cell-mediated immunity. No severe adverse pregnancy or neonatal outcomes have been consistently reported in 2019 novel coronavirus disease (COVID-19) positive pregnancy cases. There are controversies around the role of COVID-19 in pregnancy. A systematic review was conducted to examine clinical maternal and neonatal clinical outcomes. Studies were included if they reported SARS-CoV-2 infection among pregnant women and/or COVID-19 positive neonates as validated by positive antibody testing or viral testing using polymerase chain reaction. Case series, case reports, case-control studies, and comparative studies were included. Eight hundred and thirty-seven records were identified, resulting in 525 records for level I screening. Forty-one were included after full-text review.
Transmission of SARS-CoV-2 infection among children in summer schools applying stringent control measures in Barcelona, Spain

AUTHOR(S)
Iolanda Jordan; Mariona Fernandez de Sevilla; Victoria Fumado (et al.)

Published: March 2021   Journal: Clinical Infectious Diseases
Understanding the role of children in SARS-CoV-2 transmission is critical to guide decision-making for schools in the pandemic. We aimed to describe the transmission of SARS-CoV-2 among children and adult staff in summer schools.
Influence of SARS-COV-2 during pregnancy: a placental view

AUTHOR(S)
Marcos Aurélio Santos da Costa; Diana Babini Lapa de Albuquerque Britto; Jennyfer Martins de Carvalho (et al.)

Published: March 2021   Journal: Biology of Reproduction
Since the beginning of the current coronavirus outbreak (COVID-19), there has been great concern over a disease that has spread rapidly in several countries worldwide, with the result of several deaths, including deaths of pregnant women. Therefore, the aim of this study was to conduct a literature review on placental changes in infected pregnant women and/or asymptomatic carriers of COVID-19 during pregnancy, aiming at the possible vertical transmission. A systematic collection was carried out on the effects of that COVID-19 can cause directly and/or indirectly to pregnancy and the placenta in the following databases: Pubmed, Science Direct, Scielo, Lilacs, and Web of Science.
Household SARS-CoV-2 transmission and children: a network prospective study

AUTHOR(S)
Antoni Soriano-Arandes; Anna Gatell; Pepe Serrano (et al.)

Published: March 2021   Journal: Clinical Infectious Diseases
The role of children in household transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remains uncertain. Here, we describe the epidemiological and clinical characteristics of children with COVID-19 in Catalonia (Spain) and investigate the dynamics of household transmission. Prospective, observational, multicenter study performed during summer and school periods (1 July31 October, 2020), in which epidemiological and clinical features, and viral transmission dynamics were analyzed in COVID-19 patients <16 years. A pediatric index case was established when a child was the first individual infected within a household. Secondary cases were defined when another household member tested positive for SARS-CoV-2 before the child. The secondary attack rate (SAR) was calculated, and logistic regression was used to assess associations between transmission risk factors and SARS-CoV-2 infections.
Cite this research | Open access | No. of pages: 32 | Language: English | Topics: Health | Tags: COVID-19, disease transmission, family, household, infectious disease | Countries: Spain
Effectiveness of the 2019–2020 influenza vaccine and the effect of prior influenza infection and vaccination in children during the first influenza season overlapping with the COVID-19 epidemic

AUTHOR(S)
Soichiro Ando

Published: March 2021   Journal: Journal of Nippon Medical School

The behavioral changes among Japanese, along with the coronavirus disease 2019 (COVID-19) epidemic, may affect the seasonal influenza epidemic in Japan and change the influenza vaccine effectiveness (VE). Influenza VE in children was estimated in the first influenza season (2019/20) overlapping with the COVID-19 epidemic by conducting a single-center, test-negative case-control (TNCC) study. Effects of prior influenza infection and vaccination in children were assessed for the 2019–2020 season.

Prevalence of COVID-19 in adolescents and youth compared with older adults in states experiencing surges

AUTHOR(S)
Barbara Rumain; Moshe Schneiderman; Allan Geliebter

Published: March 2021   Journal: Plos One
There has been considerable controversy regarding susceptibility of adolescents (10–19 years) and youth (15–24 years) to COVID-19. However, a number of studies have reported that adolescents are significantly less susceptible than older adults. Summer 2020 provided an opportunity to examine data on prevalence since after months of lockdowns, with the easing of restrictions, people were mingling, leading to surges in cases. This study examined data from Departments of Health websites in six U.S. states experiencing surges in cases to determine prevalence of COVID-19, and two prevalence-related measures, in adolescents and youth as compared to older adults
The role of pandemic‐related pregnancy stress in preference for community birth during the beginning of the COVID‐19 pandemic in the United States

AUTHOR(S)
Heidi Preis; Brittain Mahaffey; Marci Lobel

Published: March 2021   Journal: Birth
The COVID‐19 pandemic introduced unparalleled uncertainty into the lives of pregnant women, including concerns about where it is the safest to give birth, while preserving their rights and wishes. Reports on the increased interest in community births (at home or in birth centers) are emerging. The purpose of this project was to quantitatively investigate psychological factors related to this birth preference.
Comparison of clinical severity and epidemiological spectrum between coronavirus disease 2019 and influenza in children

AUTHOR(S)
Maria Pokorska‑Śpiewak; Ewa Talarek; Jolanta Popielska (et al.)

Published: March 2021   Journal: Scientific Reports
Data on the novel coronavirus disease 2019 (COVID-19) in children are limited, and studies from Europe are scarce. This paper analyzed the clinical severity and epidemiologic aspects of COVID-19 in consecutive children aged 0–18 years, referred with a suspicion of COVID-19 between February 1, and April 15, 2020. RT-PCR on a nasopharyngeal swab was used to confirm COVID-19. 319 children met the criteria of a suspected case.
Model-based evaluation of school- and non-school-related measures to control the COVID-19 pandemic

AUTHOR(S)
Ganna Rozhnova; Christiaan H. van Dorp; Patricia Bruijning-Verhagen (et al.)

Published: March 2021   Journal: Nature Communications
The role of school-based contacts in the epidemiology of SARS-CoV-2 is incompletely understood. We use an age-structured transmission model fitted to age-specific seroprevalence and hospital admission data to assess the effects of school-based measures at different time points during the COVID-19 pandemic in the Netherlands.
Infant outcomes and maternal COVID-19 status at delivery

AUTHOR(S)
Kinga Zgutka; Kaninghat Prasanth; Shirley Pinero-Bernardo (et al.)

Published: March 2021   Journal: Physicians Weekly
This study aims to compare clinical characteristics and outcomes of infants born to COVID-19 to non COVID-19 mothers at delivery in a community hospital in Queens, New York. Case-control study conducted March 15 to June 15, 2020. Cases were infants born to mothers with laboratory-confirmed COVID-19 infection at delivery. The infant of non COVID-19 mother born before and after each case were selected as controls.
School reopening without robust COVID-19 mitigation risks accelerating the pandemic

AUTHOR(S)
Deepti Gurdasani; Nisreen A. Alwan; Trisha Greenhalgh (et al.)

Published: March 2021   Journal: The Lancet
On Feb 22, 2021, the UK Government announced that schools in England would fully reopen on March 8, 2021. While returning to school as soon as possible is imperative for the education, social development, and mental and physical welfare of children, not enough has been done to make schools safer for students and staff. Without additional mitigations, increases in transmission are likely, this time with more infectious and possibly more virulent variants, resulting in further lockdowns, school closures, and absenteeism. Even when schools were supposed to be fully open, at points of high community transmission, 22% of secondary school children were not attending due to self-isolation. In some areas, attendance was as low as 61%.
46 - 60 of 161

UNICEF Innocenti's Children and COVID-19 Library is a database collecting research from around the world on COVID-19 and its impacts on children and adolescents.

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COVID-19 & Children: Rapid Research Response

UNICEF Innocenti is mobilizing a rapid research response in line with UNICEF’s global response to the COVID-19 crisis. The initiatives we’ve begun will provide the broad range of evidence needed to inform our work to scale up rapid assessment, develop urgent mitigating strategies in programming and advocacy, and preparation of interventions to respond to the medium and longer-term consequences of the COVID-19 crisis. The research projects cover a rapid review of evidence, education analysis, and social and economic policies.