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Children and COVID-19 Research Library

UNICEF Innocenti's curated library of COVID-19 + Children research

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Factors associated with COVID‑19 vaccine uptake among adolescents and young adults recently diagnosed with cancer

Gary Kwok; Samantha Reese; Sanjana Dugad (et al.)

Published: November 2022   Journal: Journal of Adolescent and Young Adult Oncology
Adolescents and young adults (AYAs) recently diagnosed with cancer are medically vulnerable but little is known about vaccine uptake/intent in this group. AYAs reported on their COVID-19 vaccine uptake/intent. Logistic regression models examined factors associated with vaccine uptake. Higher education (adjusted odds ratio [aOR] = 1.9, 95% confidence interval [CI]: 1.0–3.5) and knowing someone diagnosed with COVID-19 (aOR = 7.2, 95% CI: 1.6–33.5) were associated with increased vaccine uptake. Prior personal diagnosis of COVID-19 (aOR = 0.1, 95% CI: 0.1–0.7) was associated with lower odds of uptake. Targeted interventions may be needed to improve uptake among this group. (ClinicalTrials.gov Identifier: NCT04585269).
Psychological distress and resilience in a multicentre sample of adolescents and young adults with cancer during the COVID-19 pandemic

Clare Jacobson; Nicola Miller; Rebecca Mulholland (et al.)

Published: December 2021   Journal: Clinical Child Psychology and Psychiatry
Understanding impact of the coronavirus pandemic (COVID-19) on Adolescents and Young Adults (AYA) with cancer is important to inform care. Online survey of 16–24 year olds receiving cancer treatment at eight cancer centres in the UK. This study measured: self-perceived increased anxiety since COVID-19, impact of COVID-19 on treatment, life and relationships, PHQ-8, GAD and the two-item Connor–Davidson Resilience Scale (CD-RISC). 112 AYA participated. 59.8% had previous mental health difficulties. 78.6% reported COVID-19 having a significant impact on life. 79% reported experiencing increased anxiety since COVID-19.43.4% had moderate-severe PHQ-8 scores and 37.1% GADS-7 scores. Impact on life was associated with moderate-severe PHQ-8 scores (OR 5.23, 95% CI 1.65–16.56, p < 0.01), impact on relationships with moderate-severe GADS-7 and PHQ-8 score (OR 2.89, 95% CI 1.11–7.54, p = 0,03; OR 3.54, 95% CI 2.32–15.17, p < 0.01; OR 2.42, 95% CI 1.11–5.25, p =0.03).
Digestive system symptoms and function in children with COVID-19

Jiajia Wang; Xiaofeng Yuan

Published: March 2021   Journal: Medicine
The prevalence of children exhibiting coronavirus disease 2019 (COVID-19) with digestive system involvement remains unknown. Therefore, this study aimed to quantify the impact of COVID-19 on the digestive system of children. This meta-analysis searched PubMed, Embase, and Web of Science from January 1, 2020, to June 31, 2020. It also searched for COVID-19 publications in specific journals for more comprehensive results. It included studies that reported the epidemiological and clinical characteristics of COVID-19, and it excluded duplicate publications, reviews, animal studies, case reports, publications without the full text, studies with incomplete information, and studies from which data extraction was impossible.
Cite this research | Vol.: 100 | Issue: 11 | No. of pages: 9 | Language: English | Tags: adolescent health, child health, COVID-19, diseases
Psychosocial and clinical effects of the COVID-19 pandemic in patients with childhood rheumatic diseases and their parents

Gizem Durcan; Kenan Barut; Fatih Haslak (et al.)

Published: January 2021   Journal: Rheumatology International
This study aimed to evaluate the psychological symptoms of children and adolescents with rheumatological diseases (RD) and their parents during the outbreak. A web-based questionnaire survey was conducted in a cross-sectional design in RD patients and healthy controls. The Hospital Anxiety and Depression Scale was used to evaluate parental psychiatric status; while the State-Trait Anxiety Inventory for Child was used for children. Four hundred and ffty-nine patients with RD and their parents completed the present study, as well as 336 healthy peers. The age and gender of the children were similar across groups.
COVID‐19 and children with cancer: parents’ experiences, anxieties and support needs

Anne‐Sophie E. Darlington; Jessica E. Morgan; Richard Wagland (et al.)

Published: November 2020   Journal: Pediatric Blood & Cancer

Children with cancer were designated as clinically extremely vulnerable if they were to contract SARS‐CoV‐2 due to immune suppression in the early phase of the COVID‐19 pandemic. Our aim was to explore experiences, information and support needs, and decision making of parents with a child with cancer in response to this phase in the United Kingdom. Parents of a child with cancer completed a survey at a time when the UK moved into a period of ‘lockdown’. An online survey was developed by the research team to capture parents’ experiences, information and support needs, and decision making, using closed statements and open text boxes. Descriptive quantitative analyses and qualitative thematic content analysis were undertaken.

Cite this research | Open access | Vol.: 68 | Issue: 2 | Language: English | Topics: Health | Tags: child health, COVID-19 response, diseases, lockdown, parents | Countries: United Kingdom
Migraine symptoms improvement during the COVID-19 lockdown in a cohort of children and adolescents

Gianfranco Dallavalle; Elena Pezzotti; Livio Provenzi (et al.)

Published: October 2020   Journal: Frontiers in Neurology
Pediatric migraine is among the most common primary or comorbid neurologic disorders in children. Psychological stressors are widely acknowledged as potential triggers involved in recurring episodes of pediatric migraine. As the COVID-19 emergency may have affected the levels of stress perceived by children and adolescents with migraine, the present study was aimed to understand the effect of COVID-19 emergency on symptoms intensity and frequency in pediatric patients.
Unique needs of childhood cancer survivors during the COVID-19 pandemic

Victoria J. Forster; Fiona Schulte

Published: October 2020   Journal: Supportive Care in Cancer
Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a global health pandemic that has caused significant morbidity and mortality for individuals worldwide. Survivors of childhood cancer (CCS) may be especially vulnerable to both the physical and mental health impacts of COVID-19. Despite publications highlighting the unique risks for survivors of cancer amid COVID-19, little attention has focused on the specific needs of CCS. The aim of this commentary, therefore, is to highlight the unique physical and mental health needs of CCS to better inform healthcare professionals (HCPs) that may encounter CCS during the pandemic.
Cite this research | No. of pages: 17-19 | Language: English | Topics: Health, Mental Health | Tags: child health, child mental health, diseases
War on two fronts: experience of children with cancer and their family during COVID-19 pandemic in Iran

Jila Mirlashari; Fatemeh Ebrahimpour; Waliu Jawula Salisu

Published: October 2020   Journal: Journal of Pediatric Nursing
The COVID-19 pandemic affects all age groups and presents differently in children from adults. Children who contract the virus while suffering from cancer may face unique health challenges than their counterparts. This study aimed to investigate the perspectives of children with cancer and their family in this era of the COVID-19 pandemic. In this qualitative study, a total of 21 participants were interviewed. They include five children, thirteen mothers, a father and three pediatric oncology nurses. The study setting was a Pediatric Hospital in Tehran, Iran.Three main themes were identified through thematic analysis. 1) Swinging on the path of fear to adaptation, 2) Left-alone at emotional distances, 3) Care system confusion, and decreased quality of care.
Management of hepatitis C in children and adolescents during COVID-19 pandemic

Maria Pokorska-Śpiewak; Mateusz Śpiewak

Published: August 2020   Journal: World Journal of Hepatology
In recent years, significant progress in the antiviral treatment of chronic hepatitis C (CHC) has been made due to the development of interferon-free therapies. Three different highly effective, oral direct-acting antiviral (DAA) regimens have been approved for use in adolescents with CHC between the ages of 12-years-old and 17-years-old in Europe. According to the current recommendations, all treatment-naïve and treatment-experienced children with CHC virus infection should be considered for DAA therapy to prevent the possible progression of hepatitis C virus-related liver disease and its complications. However, the novel coronavirus disease 2019 outbreak, which was classified as a pandemic in March 2020, is currently spreading throughout the world, resulting in a disruption of the healthcare system. This disruption is having a negative impact on the care of patients with chronic diseases, including children with CHC. Thus, several efforts have to be made by pediatric hepatologists to prioritize patient care in children with CHC. These efforts include promoting telemedicine in the outpatient setting, using local laboratory testing for follow-up visits, and engaging in the home delivery of DAAs for patients under antiviral therapy whenever possible.
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UNICEF Innocenti's Children and COVID-19 Library is a database collecting research from around the world on COVID-19 and its impacts on children and adolescents.


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