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Children and COVID-19 Research Library

UNICEF Innocenti's curated library of COVID-19 + Children research

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1 - 15 of 56
Global research priorities for COVID-19 in maternal, reproductive and child health: Results of an international survey

AUTHOR(S)
Melanie Etti; Jackeline Alger; Sofía P. Salas (et al.)

Published: September 2021   Journal: Plos One

The World Health Organization’s “Coordinated Global Research Roadmap: 2019 Novel Coronavirus” outlined the need for research that focuses on the impact of COVID-19 on pregnant women and children. More than one year after the first reported case significant knowledge gaps remain, highlighting the need for a coordinated approach. To address this need, the Maternal, Newborn and Child Health Working Group (MNCH WG) of the COVID-19 Clinical Research Coalition conducted an international survey to identify global research priorities for COVID-19 in maternal, reproductive and child health. This project was undertaken using a modified Delphi method. An electronic questionnaire was disseminated to clinicians and researchers in three different languages (English, French and Spanish) via MNCH WG affiliated networks. Respondents were asked to select the five most urgent research priorities among a list of 17 identified by the MNCH

The effect of online solution-focused brief therapy on parents with high level of anxiety in the COVID 19 pandemic: a randomized controlled study

AUTHOR(S)
Mürşide Zengin; Ceyda Başoğul; Emriye Hilal Yayan

Published: September 2021   Journal: International Journal of Clinical Practice is

The aim of this study was to determine the anxiety levels of parents with children aged 3-6 years because of the Coronavirus Disease 2019 (COVID-19) pandemic and to examine the effects of Solution-Focused Support Program (SFSP) applied to parents with a high level of anxiety. The study was conducted as a parallel-group, randomised controlled design. The sample of the study consisted of 77 parents who were randomly assigned to the experimental and control groups (control group n = 40; intervention group n = 37). One session of online SFSP was applied to the intervention group each week and 4 sessions were applied in total. No intervention was applied to the control group. 

COVID-19 and UK family carers: policy implications

AUTHOR(S)
Juliana Onwumere; Cathy Creswell; Gill Livingston (et al.)

Published: September 2021   Journal: The Lancet Psychiatry

Informal (unpaid) carers are an integral part of all societies and the health and social care systems in the UK depend on them. Despite the valuable contributions and key worker status of informal carers, their lived experiences, wellbeing, and needs have been neglected during the COVID-19 pandemic. This Health Policy brings together a broad range of clinicians, researchers, and people with lived experience as informal carers to share their thoughts on the impact of the COVID-19 pandemic on UK carers, many of whom have felt abandoned as services closed. It focuses on the carers of children and young people and adults and older adults with mental health diagnoses, and carers of people with intellectual disability or neurodevelopmental conditions across different care settings over the lifespan. It provides policy recommendations with the aim of improving outcomes for all carers.



A cross-sectional survey exploring the impact of the COVID-19 pandemic on the cancer care of adolescents and young adults

AUTHOR(S)
Kaitlyn Howden; Camille Glidden; Razvan G. Romanescu (et al.)

Published: August 2021   Journal: Current Oncology
This study aimed to describe the negative and positive impacts of changes in cancer care delivery due to COVID-19 pandemic for adolescents and young adults (AYAs) in Canada, as well as the correlates of negative impact and their perspectives on optimization of cancer care. It conducted an online, self-administered survey of AYAs with cancer living in Canada between January and February 2021. Multiple logistic regression was used to identify factors associated with a negative impact on cancer care. Of the 805 participants, 173 (21.5%) experienced a negative impact on their cancer care including delays in diagnostic tests (11.9%), cancer treatment (11.4%), and appointments (11.1%). A prior diagnosis of mental or chronic physical health condition, an annual income of <20,000 CAD, ongoing cancer treatment, and province of residence were independently associated with a negative cancer care impact (p-value < 0.05). The majority (n = 767, 95.2%) stated a positive impact of the changes to cancer care delivery, including the implementation of virtual healthcare visits (n = 601, 74.6%). Pandemic-related changes in cancer care delivery have unfavorably and favorably influenced AYAs with cancer. Interventions to support AYAs who are more vulnerable to the adverse effects of the pandemic, and the thoughtful integration of virtual care into cancer care delivery models is essential.
Cite this research | Open access | Vol.: 28 | Issue: 4 | No. of pages: 13 | Language: English | Topics: Health | Tags: adolescent health, COVID-19 response, health care, health services, lockdown, social distance | Countries: Canada
Economic Crisis and Child Well-being in the West and Central Africa Region
The COVID-19 pandemic that swept over the world from early 2020 has triggered both health and economic shocks of unprecedented proportions in recent memory. Some estimates suggest that the consequences of these shocks will likely erase most of the progress made in global development over the past two decades. Many countries now risk falling further behind the attainment of national and international development goals, including the UN’s Sustainable Development Goals. Children are particularly vulnerable to the effects of these shocks due to their persistent higher levels of vulnerability, and the reality that school closures and other COVID-19 containment measures can be more damaging to children. 

This report examines the effect of previous economic crises on children’s well-being in UNICEF’s West and Central Africa Region (WCAR) and makes projections regarding the potential impacts of COVID-19-induced economic crises on priority indicators for the region. 
COVID-19 in children with cancer and continuation of cancer-directed therapy during the infection

AUTHOR(S)
Badira Cheriyalinkal Parambil; Nirmalya Roy Moulik; Chetan Dhamne (et al.)

Published: August 2021   Journal: Indian Journal of Pediatrics

This study aims to report the experience with COVID-19 in children with cancer at the largest tertiary-cancer care and referral center in India. This study is a single tertiary center experience on COVID-19 in children with cancer and continuation of cancer-directed therapy in them. Children ≤ 15 y on active cancer treatment detected with COVID-19 until September 15th, 2020 were prospectively followed up in the study. Patients were managed in accordance with well-laid guidelines. Treatment was continued for children with COVID-19 who were clinically stable and on intensive treatment for various childhood cancers.

Ethical responsibilities of European children’s teams facing the resurgent COVID-19 pandemic

AUTHOR(S)
Anna Zanin; Enrico Furlan; Marek Migdal (et al.)

Published: July 2021   Journal: European Journal of Pediatrics
The COrona VIrus Disease 2019 (COVID-19) pandemic is posing an unprecedented challenge to healthcare systems around the globe. Europe has been struggling for 1 year now, and despite some encouraging progress (above all, the beginning of vaccination), the second wave is ongoing. Even though children are less affected than adults, the COVID-19 pandemic—and in particular the measures to counter it—is having a considerable impact on the paediatric healthcare setting. It is, therefore, the duty of paediatric teams in Europe to prepare for the challenges ahead. We wish to contribute to this necessary preparedness in two ways: firstly, by assessing the direct and indirect impact of the pandemic on children and on the paediatric setting; secondly, and more importantly, by identifying the various responsibilities of paediatric healthcare professionals, in light of established ethical principles.
Healthcare professionals’ experiences of the barriers and facilitators to paediatric pain management in the community at end-of-life: a qualitative interview study

AUTHOR(S)
Katie Greenfield; Bernie Carter; Emily Harrop (et al.)

Published: July 2021   Journal: Journal of Pain and Symptom Management

Inadequate pain management in community paediatric palliative care is common. Evidence to inform improved pain management in this population is limited. To explore the barriers and facilitators to paediatric community-based pain management for infants, children and young people at end-of-life as perceived by healthcare professionals.

Global changes in maternity care provision during the COVID-19 pandemic: a systematic review and meta-analysis

AUTHOR(S)
Rosemary Townsend; Barbara Chmielewska; Imogen Barratt (et al.)

Published: June 2021   Journal: EClinicalMedicine
The COVID-19 pandemic has had a profound impact on healthcare systems globally, with a worrying increase in adverse maternal and foetal outcomes. This study aimed to assess the changes in maternity healthcare provision and healthcare-seeking by pregnant women during the COVID-19 pandemic. It performed a systematic review and meta-analysis of studies of the effects of the pandemic on provision of, access to and attendance at maternity services.
Resilience and vulnerability of maternity services in Zimbabwe: a comparative analysis of the effect of Covid-19 and lockdown control measures on maternal and perinatal outcomes, a single-centre cross-sectional study at Mpilo Central Hospital

AUTHOR(S)
Clare Shakespeare; Handsome Dube; Sikhangezile Moyo (et al.)

Published: June 2021   Journal: BMC Pregnancy and Childbirth

On the 27th of March 2020 the Zimbabwean government declared the Covid-19 pandemic a ‘national disaster’. Travel restrictions and emergency regulations have had significant impacts on maternity services, including resource stock-outs, and closure of antenatal clinics during the lockdown period. Estimates of the indirect impact of Covid-19 on maternal and perinatal mortality was expected it to be considerable, but little data was yet available. This study aimed to examine the impact of Covid-19 and lockdown control measures on non-Covid outcomes in a government tertiary level maternity unit in Bulawayo, Zimbabwe, by comparing maternal and perinatal morbidity and mortality before, and after the lockdown was implemented.

Refugees and migrants in times of COVID-19: mapping trends of public health and migration policies and practices
Institution: World Health Organisation
Published: June 2021
Refugees and migrants have been disproportionately affected by both the direct effects of the COVID-19 pandemic and the restrictive migration measures put in place, which, in turn, have hampered coordinated and consistent public health responses. This report maps how the needs of refugee and migrant have been addressed in COVID-19 responses across countries and how these have varied considerably from inclusive policies to discriminatory practices. Many countries ensured access to health care for refugees and migrants regardless of migration status, and several countries also suspended forced returns and prioritized alternatives to immigration detention. An integrated approach to migration and public health policies covering protection-sensitive access to territories, a flexible approach to migration status and non-discriminatory access to health care is suggested as a policy consideration to uphold international conventions protecting the right to health without discrimination for refugees and migrants.
Parent training intervention for autism symptoms, functional emotional development, and parental stress in children with autism disorder: a randomized clinical trial

AUTHOR(S)
Afsaneh Akhani; Mahmood Dehghani; Banafsheh Gharraee (et al.)

Published: June 2021   Journal: Asian Journal of Psychiatry

Today, early interventions to treat autistic children through parent training interventions is of outmost importance. Interventions are focused on developmental or behavioral approaches and are mostly individual or group ones. In the present study, both proposed approaches in the form of structured individual and group parent training sessions among Iranian families are investigated. This study was a randomized clinical trial which was performed in 2019–2020 in Tehran.

Improving clinical paediatric research and learning from COVID-19: recommendations by the Conect4Children expert advice group

AUTHOR(S)
Athimalaipet V. Ramanan; Neena Modi; Saskia N. de Wildt (et al.)

Published: June 2021   Journal: Pediatric Research

The COVID-19 pandemic has had a devastating impact on multiple aspects of healthcare, but has also triggered new ways of working, stimulated novel approaches in clinical research and reinforced the value of previous innovations. Conect4children (c4c, www.conect4children.org) is a large collaborative European network to facilitate the development of new medicines for paediatric populations, and is made up of 35 academic and 10 industry partners from 20 European countries, more than 50 third parties, and around 500 affiliated partners. This study summarises aspects of clinical research in paediatrics stimulated and reinforced by COVID-19 that the Conect4children group recommends regulators, sponsors, and investigators retain for the future, to enhance the efficiency, reduce the cost and burden of medicines and non-interventional studies, and deliver research-equity.

Care of pediatric patients with diabetes during the COVID-19 pandemic

AUTHOR(S)
Colleen Buggs-Saxton

Published: May 2021   Journal: Pediatric Clinics of North America
This  article  summarizes  clinical  observations  and  management  strategies  in  pediatric type 1 diabetes (T1D) during the COVID-19 pandemic.  Despite initial fears that children with diabetes would, similar to adults with diabetes, be at risk for severe COVID-19, the majority  of  pediatric  patients  with  a  history  of  type  1  diabetes  (T1D)  who  developed COVID-19 had  mild  disease  or  were  asymptomatic  similar  to  their  peers  without diabetes.  Studies found that pediatric patients with new-onset diabetes often presented with more severe diabetic ketoacidosis (DKA) in part due to both parental anxiety with seeking emergency medical care and systemic barriers to accessing health care during a pandemic.  The article also summarizes the use of telemedicine to provide ongoing care for  pediatric  patients  with  T1D  during  the  COVID-19  pandemic.    Finally,  the  article highlights  important  lessons  learned  about  management  of  pediatric  diabetes  during the COVID-19 pandemic.
Cite this research | Open access | No. of pages: 19 | Language: English | Topics: Health | Tags: child health, COVID-19, diabetes, health care, health services
Impact of COVID-19 on pediatric Immunocompromised patients

AUTHOR(S)
James A. Connelly; Hey Chong; Adam J. Esbenshade (et al.)

Published: May 2021   Journal: Pediatric Clinics of North America
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has caused critical coronavirus disease (COVID-19) most often in the elderly and individuals with co-morbid medical conditions. Although growing evidence supports the importance of an intact innate immune response at the onset of viral infection, mortality caused by dysregulated immune responses, particularly in adults, has shown a spotlight on the delicate balance of a robust, but coordinated and controlled immune activity against infection.  This complex network of infection, immune response, and inflammation with SARS-CoV-2 has created concerns, questions, and challenges for immunocompromised children beyond fear of death from contracting SARS-CoV-2. This review examines how adaptations by health care systems to reduce SARS-CoV-2 transmission and treat the surge of COVID-19 patients impacted immunocompromised pediatric patients.

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UNICEF Innocenti's Children and COVID-19 Library is a database collecting research from around the world on COVID-19 and its impacts on children and adolescents.

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COVID-19 & Children: Rapid Research Response

UNICEF Innocenti is mobilizing a rapid research response in line with UNICEF’s global response to the COVID-19 crisis. The initiatives we’ve begun will provide the broad range of evidence needed to inform our work to scale up rapid assessment, develop urgent mitigating strategies in programming and advocacy, and preparation of interventions to respond to the medium and longer-term consequences of the COVID-19 crisis. The research projects cover a rapid review of evidence, education analysis, and social and economic policies.