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Children and COVID-19 Research Library

UNICEF Innocenti's curated library of COVID-19 + Children research

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1 - 15 of 145
Increasing trend in violence-related trauma and suicide attempts among pediatric trauma patients: a 6-year analysis of trauma mechanisms and the effects of the COVID-19 pandemic

AUTHOR(S)
Cecilia Maina; Stefano Piero Bernardo Cioffi; Michele Altomare (et al.)

Published: January 2023   Journal: Journal of Personalized Medicine
Trauma is the leading cause of morbidity and mortality in the pediatric population. During the COVID-19 pandemic (COVID-19), different trends for pediatric trauma (PT) were described. This study aims to explore the trend over time of PT in our center, also considering the effects of COVID-19, focusing on trauma mechanisms, violence-related trauma (VRT) and intentionality, especially suicide attempts (SAs). All PT patients accepted at Niguarda Trauma Center (NTC) in Milan from January 2015 to December 2020 were retrospectively analyzed.
Cite this research | Open access | Vol.: 13 | Issue: 1 | No. of pages: 11 | Language: English | Topics: Health | Tags: child health, COVID-19 response, hospitalization, lockdown, social distance, traumatized children | Countries: Italy
Risk factors for death among children and young people hospitalized with COVID-19: a literature review

AUTHOR(S)
Bi Ze; Bin Chen; Xiaoshan Ji (et al.)

Published: December 2022   Journal: Pediatric Medicine

Coronavirus disease 2019 (COVID-19) has been a most important global issue since December 2019. Although for children, the clinical course of COVID-19 is milder, it may still cause a multi-system inflammatory syndrome and has rendered 22,000 deaths among children and young people. The objective of this review is to provide an up-to-date information about COVID-19 related mortality and relevant risk factors in children and young people. This study provides a narrative review of COVID-19 related mortality and relevant risk factors in children and young people. Electronic searches for studies were conducted using PubMed and Web of Science, with a date time up to April 22, 2022. 22, 2022. Only publications in English were included.

Do parents vaccinated against COVID-19 protect their children from hospitalization due to COVID-19?

AUTHOR(S)
Ömer Günes; Belgin Gülhan; Ahmet Yasin Guney (et al.)

Published: December 2022   Journal: Journal of Tropical Pediatrics

This study aimed to determine whether parental vaccination against coronavirus disease 2019 (COVID-19) prevents hospitalization of COVID-19-infected children. This study was based on data obtained from the records of pediatric patients that were followed up for virologically proven COVID-19 infection between August and October 2021, during which time the delta variant was dominant in Turkey and the children were isolating at home.

The psychological impact of COVID-19 admission on families: results from a nationwide sample in Greece

AUTHOR(S)
Despoina Gkentzi; Konstantinos Mhliordos; Ageliki Karatza (et al.)

Published: December 2022   Journal: Children
The aim of the present study was to assess the psychological impact of hospitalization during the COVID-19 pandemic on parents and their offspring. We performed a nationwide cross-sectional study in Greece based on an Internet questionnaire survey. A convenience sample of parents whose offspring had been hospitalized due to COVID-19 (including multisystem inflammatory syndrome in children, MIS-C), diagnosed with COVID-19 but not hospitalized, and hospitalized for another reason during the pandemic were enrolled. Parental stress was assessed using the Perceived Stress Scale (PSS) and the Revised Impact of Event Scale (IES-R) tools, and childhood mental wellbeing with the Children’s Revised Impact of Event 13 (CRIES-13) scale.
Cite this research | Open access | Vol.: 9 | Issue: 12 | No. of pages: 10 | Language: English | Topics: Health, Mental Health | Tags: child health, COVID-19, hospitalization, infectious disease, mental stress, parents, psychological distress | Countries: Greece
Management of multisystem inflammatory syndrome in children (MIS-C) in resource limited settings: the Kenyan experience

AUTHOR(S)
Angela Migowa; Pauline Samia; Sean del Rossi (et al.)

Published: December 2022   Journal: Pediatric Rheumatology

Since the onset of the recent COVID-19 pandemic, there have been growing concerns regarding multisystem inflammatory syndrome in children (MIS-C). This study aims to describe the clinico-epidemiological profile and challenges in management of MIS-C in low-middle income countries by highlighting the Kenyan experience. A retrospective study at the Aga Khan University Hospital Nairobi, Avenue Hospital Kisumu and Kapsabet County Referral Hospital was undertaken to identify cases of MIS-C. A detailed chart review using the World Health Organization (WHO) data collection tool was adapted to incorporate information on socio-demographic details and treatment regimens.

Psychological experience of Juvenile patients' parents in Fangcang shelter hospital during the Omicron wave of COVID-19 pandemic in Shanghai, China: a qualitative study

AUTHOR(S)
Hongmei Wu; Kexi Liao; Caidie Yang (et al.)

Published: November 2022   Journal: BMC Public Health

This study aims to explore the psychological experience of Juvenile patient’s parents in Fangcang shelter hospital during the Omicron wave of COVID-19 pandemic. A qualitative study was conducted by using a phenomenological research method. Sixteen parents of juvenile patients with COVID-19 were recruited from National Exhibition and Convention Center (Shanghai, China) Fangcang shelter hospital (FSH) using purposive sampling. Data were collected by face-to-face in-depth interviews over 27 days, from April 9 to May 6, 2022. The interview data were analyzed using Colaizzi seven-step analysis method.

In-hospital mortality of COVID-19 in Iranian children and youth: a multi-centre retrospective cohort study

AUTHOR(S)
Pedram Fattahi; Sepideh Abdi; Elnaz Saeedi (et al.)

Published: November 2022   Journal: Journal of Global Health

COVID-19 presents as a mild and less severe respiratory disease among children. However, it is still lethal and could lead to death in paediatric cases. The current study aimed to investigate the clinical characteristics of children and young people hospitalized due to COVID-19 in Qazvin-Iran. We also investigated the risk factors of death due to COVID-19 in paediatric cases. We performed a retrospective cohort study on 645 children and young people (ages 0-17) hospitalized since the beginning of the COVID-19 pandemic. The cases were confirmed with positive results of reverse transcription-polymerase chain reaction (RT-PCR). The data were retrieved from an electronic database of demographic, epidemiological, and clinical characteristics.

Evaluating the impact of COVID-19 on severity at admission and response to inpatient treatment for adult and adolescent patients with eating disorders

AUTHOR(S)
Colleen C. Schreyer; Irina A. Vanzhula; Angela S. Guarda

Published: November 2022   Journal: International Journal of Eating Disorders

The COVID-19 pandemic has been associated with increased hospitalization rates and worsened symptom severity in patients with eating disorders (ED), but most studies focused exclusively on adolescents. Further, research evaluating the impact of COVID-19 on response to inpatient treatment for ED is limited. This study aimed to compare demographic characteristics, symptom severity at admission, and discharge outcomes for adult and adolescent inpatients with EDs admitted before and after onset of the COVID-19 pandemic.  The post-COVID cohort was expected to report elevated symptomatology and poorer response to treatment compared to the pre-COVID cohort and this effect was expected to be amplified for adolescents. Patients were consecutively hospitalized adults and adolescents treated in a specialized behavioral integrated inpatient-partial hospitalization program for eating disorders between March 2018 and March 2022 (N = 261).

The association between pre-existing asthma and reduced risk of death among children and adolescents hospitalized with COVID-19 in Brazil

AUTHOR(S)
Maria C. L. Oliveira; Enrico A. Colosimo; Mariana A. Vasconcelos (et al.)

Published: November 2022   Journal: Pediatric Pulmonology

There have been conflicting reports on the relationship between asthma and COVID-19 severity. This study aimed to compare the risk of death among children with asthma and healthy peers hospitalized due to COVID-19. It carried out an analysis of all pediatric patients 2–19 years of age with asthma and COVID-19 registered in Influenza Epidemiological Surveillance Information System-Gripe, a Brazilian nationwide surveillance database, between February 2020 and March 2022. The primary outcome was time to death, which was evaluated considering discharge as a competitive risk using the cumulative incidence function.

Impact of Covid-19 pandemic on children with special needs requiring general anaesthesia for the treatment of dental disease: the experience of the Brescia Children's Hospital, Lombardy, Italy

AUTHOR(S)
K. Tewfik; C. Peta; M. C. De Giuli (et al.)

Published: November 2022   Journal: European Archives of Paediatric Dentistry

Special needs children presenting with dental problems were penalised during the Covid-19 pandemic due to the reduction of clinical activity and the risks of nosocomial infection. The aim of this study is to evaluate the impact of the pandemic on oral healthcare in paediatric special needs patients. It retrospectively assessed and compared the outpatient clinic activity and dental procedures performed under general anaesthesia in children with special needs at Brescia Children’s Hospital (Italy) in 2019, 2020, and 2021. Any delay between expected waiting time based on assigned priority and surgery was recorded. The efficacy of the protocol adopted to reduce the spread of Covid-19 was evaluated by reporting any infections in patients, parents, and health care providers.

Cite this research | Open access | Issue: 11 | No. of pages: 6 | Language: English | Topics: Health | Tags: child health, COVID-19 response, health services, hospitalization, lockdown, social distance | Countries: Italy
Consequences of COVID-19-related lockdowns and reopenings on emergency hospitalizations in pediatric patients in Denmark during 2020-2021

AUTHOR(S)
Rada Faris Al-Jwadi; Elisabeth Helen Anna Mills; Christian Torp-Pedersen (et al.)

Published: November 2022   Journal: European Journal of Pediatrics (
There is a considerable burden of children being hospitalized due to infectious diseases worldwide. The COVID-19 pandemic provided a unique opportunity to examine effects of worldwide efforts to control spread of infection. We aimed to investigate overall age-specific hospitalizations due to viral and bacterial infections and diseases triggered by respiratory tract infections during and after lockdown. This nationwide register–based observational study included children from 29 days to 17 years old hospitalized in all Danish pediatric emergency departments during the years 2015–2021.
A comparative analysis of the occurrence of lower respiratory tract infections caused by respiratory syncytial virus among newborns in the years before and during Covid-19 pandemic at a tertiary referral hospital in Slovenia

AUTHOR(S)
Sandra Cerar; Vesna Pirnovar

Published: November 2022   Journal: Central European Journal of Paediatrics

This study aimed to compare the occurrence of lower respiratory tract infections caused by respiratory syncytial virus in the neonatal population in the years before and during the COVID-19 pandemic. Cases of newborns, hospitalized due to viral lower respiratory tract infection from 2015 to 2020, were analyzed retrospectively, and compared according to cause (respiratory syncytial virus, non-respiratory syncytial virus) and treatment requirements before (2015−2019) and after (2020) the outbreak of the COVID-19 pandemic.

Cite this research | Open access | Vol.: 18 | Issue: 2 | No. of pages: 8 | Language: English | Topics: Health | Tags: child health, COVID-19, hospitalization, infectious disease, postnatal care, respiratory diseases | Countries: Slovenia
Identifying parent anxiety and family distress of critically ill children in response to changes in hospital visitation policies during the COVID-19 pandemic

AUTHOR(S)
Jodi J. Bloxham; Paula Levett; Jihye Lee (et al.)

Published: October 2022   Journal: Journal of Pediatric Nursing
This research study describes parent anxiety and family distress among three study groups of varying restrictions in parent presence for children in the PICU during a pandemic. A retrospective study was conducted to describe differences in parent anxiety and family distress for parents of children hospitalized before and during the COVID-19 pandemic. Participants fell into three study groups based on the dates of the child's hospital stay and the level of parent and family presence or restriction they experienced. Participants were asked to complete a survey that included basic demographic information along with utilization of the GAD-7 and FDI measures. The data were assessed using descriptive statistics, Fisher's exact test, and the Kruskal-Wallis test.
Clinical course of COVID-19 in hospitalized children of Ukraine in different pandemic periods

AUTHOR(S)
Iryna Seriakova; Vitalii Yevtushenko; Sergiy Kramarov (et al.)

Published: October 2022   Journal: European Clinical Respiratory Journal

The coronavirus infection (COVID-19) pandemic has seen a progressive increase in childhood morbidity worldwide. Continuous mutation of the SARS-CoV-2 virus causes the wave-like course of the COVID-19 pandemic, which is characterized by an undulating course and the predominance of different variants of the SARS-CoV-2 virus. There are many reports that the clinical picture may vary depending on the circulating strain of the virus [7–11, 13–16]. Based on this, we decided to analyze and evaluate the presence of a pattern between the clinical and epidemic COVID-19 characteristics and the strain of the SARS-CoV-2 virus prevailing locally. To study the effects of various strains of SARS-CoV-2 on the clinical and epidemiological characteristics of pediatric patients; to determine the regularity between the severity of the disease and the circulating strain of SARS-CoV-2.

Cite this research | Open access | Vol.: 9 | Issue: 1 | No. of pages: 10 | Language: English | Topics: Health | Tags: child health, COVID-19 response, health services, hospitalization, lockdown, social distance
The incidence and causes of acute hospitalizations and emergency room visits in adolescents with type 1 diabetes mellitus prior to and during the COVID-19 pandemic: a single-centre experience

AUTHOR(S)
Zuzanna Nowak; Jakub Gawlik; Anna Wędrychowicz (et al.)

Published: October 2022   Journal: Pediatric Endocrinology, Diabetes and Metabolism

 Type 1 diabetes mellitus (T1DM) is one of the most common chronic diseases in childhood. Because acute glycaemic com-plications account for most concerns in the management of T1DM in children, special attention during the challenging time of the global COVID-19 pandemic is required to prevent deteriorations resulting in acute hospitalization. Aim of the study is to assess how the COVID-19 pandemic influenced the incidence and causes of acute hospitalizations and emergency room visits in adolescents with established type 1 diabetes mellitus, and to characterize the admitted population. The study was conducted as a retrospective evaluation of acute hospitalizations of 39 T1DM patients between 15 and 17 years of age in the period 2018-2021.

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COVID-19 & Children: Rapid Research Response

UNICEF Innocenti is mobilizing a rapid research response in line with UNICEF’s global response to the COVID-19 crisis. The initiatives we’ve begun will provide the broad range of evidence needed to inform our work to scale up rapid assessment, develop urgent mitigating strategies in programming and advocacy, and preparation of interventions to respond to the medium and longer-term consequences of the COVID-19 crisis. The research projects cover a rapid review of evidence, education analysis, and social and economic policies.