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Children and COVID-19 Research Library

UNDER DEVELOPMENT UNICEF Innocenti's curated library of COVID-19 + Children research

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Supporting parents as essential care partners in neonatal units during the SARS‐CoV‐2 pandemic

AUTHOR(S)
Nicole R. van Veenendaal; Aniko Deierl; Fabiana Bacchini (et al.)

Published: March 2021   Journal: Acta Paediatrica

This study aims to review the evidence on safety of maintaining family integrated care practices and the effects of restricting parental participation in neonatal care during the SARS‐CoV‐2 pandemic. MEDLINE, EMBASE, PsycINFO and CINAHL databases were searched from inception to the 14th of October 2020. Records were included if they reported scientific, empirical research (qualitative, quantitative, or mixed methods) on the effects of restricting or promoting family integrated care practices for parents of hospitalized neonates during the SARS‐CoV‐2 pandemic. Two authors independently screened abstracts, appraised study quality and extracted study and outcome data.

Care of hospitalized infants and their families during the COVID-19 pandemic: an international survey

AUTHOR(S)
Ita Litmanovitz; Dalia Silberstein; Samantha Butler (et al.)

Published: March 2021   Journal: Journal of Perinatology
This research study explored changes in family-centered care practices for hospitalized infants and families due to the COVID-19 pandemic. This exploratory descriptive study used a 49-item online survey, distributed to health care professionals working with hospitalized infants and families. The sample consisted of 96 participants from 22 countries.
The severity and atypical presentations of COVID-19 infection in pediatrics

AUTHOR(S)
Nagwan Y. Saleh; Hesham M. Aboelghar; Sherif S. Salem (et al.)

Published: March 2021   Journal: BMC Pediatrics
Emergence of 2019-nCoV attracted global attention and WHO declared COVID-19 a public health emergency of international concern. Therefore this study aimed to explore the severity and atypical manifestations of COVID-19 among children. This is an observational cohort study conducted on 398 children with confirmed COVID-19 by using realtime reverse transcriptase polymerase chain reaction assay for detection of 2019-nCoV nucleic acid during the period from March to November 2020. Patients were subdivided regarding the severity of COVID-19 presentation into Group I (Non-severe COVID-19) was admitted into wards and Group II (Severe COVID-19) admitted into the PICU.
Maintaining maternal–newborn safety during the COVID-19 pandemic

AUTHOR(S)
Nancy A. Patric; Teresa S. Johnson

Published: March 2021   Journal: Nursing for Women's Health
COVID-19, the disease caused by the SARS-CoV-2 virus, was declared a global pandemic by the World Health Organization on March 11, 2020. In addition to older individuals and those with underlying chronic health conditions, maternal and newborn populations were also identified as being at greater risk. It became critical for hospitals and clinicians to maintain the safety of individuals in the facility and minimize the transmission of COVID-19 while continuing to strive for optimized outcomes by providing family-centered care. Rapid change during the pandemic made it appropriate to use the plan–do–study–act (PDSA) cycle to continually evaluate proposed and standard practices. Our team established an obstetric COVID-19 unit for women and newborns, developed guidelines for visitation and for the use of personal protective equipment, initiated universal COVID-19 testing, and provided health education to emphasize shared decision making.
Child and pet care‐planning during COVID‐19: considerations for the evolving family unit

AUTHOR(S)
Britni L. Adams; Jennifer W. Applebaum; Michelle N. Eliasson (et al.)

Published: March 2021   Journal: Family Relations

Using a mixed‐methods design, this paper aimed to understand household dynamics and choices in hypothetical planning for child and pet care if an individual is faced with hospitalization for COVID‐19. As the COVID‐19 public health crisis persists, children and pets are vulnerable to caregiver hospitalization.

The role of pandemic‐related pregnancy stress in preference for community birth during the beginning of the COVID‐19 pandemic in the United States

AUTHOR(S)
Heidi Preis; Brittain Mahaffey; Marci Lobel

Published: March 2021   Journal: Birth
The COVID‐19 pandemic introduced unparalleled uncertainty into the lives of pregnant women, including concerns about where it is the safest to give birth, while preserving their rights and wishes. Reports on the increased interest in community births (at home or in birth centers) are emerging. The purpose of this project was to quantitatively investigate psychological factors related to this birth preference.
Unintended consequences of restrictive visitation policies during the COVID-19 pandemic: implications for hospitalized children

AUTHOR(S)
Jean L. Raphael; Woodie Kessel; Mona Patel

Published: March 2021   Journal: Pediatric research
The COVID-19 pandemic has resulted in devastating consequences worldwide with over 2,000,000 deaths. Although COVID-19 demonstrates less morbidity and mortality among children,1 it has dramatically altered the health-care experience for children and families. This is particularly true for those cared for in inpatient settings. The competing priorities of safeguarding families and health-care personne from a serious infection, stewardship of limited resources, ensuring family-centered care (FCC), and carrying out end-of-life care have led to tensions in how to effectively implement and execute necessary restrictive visitation policies. While the Centers for Disease Control and Prevention (CDC) provides broad guidelines to health-care facilities on the management of visitors, hospitals must determine how to implement such guidelines.
‘Do I, don’t I?’ a qualitative study addressing parental perceptions about seeking healthcare during the COVID-19 pandemic

AUTHOR(S)
Gabriella Watson; Lucy Pickard; Bhanu Williams (et al.)

Published: March 2021   Journal: Archives of disease in childhood
Paediatric emergency departments have seen reduced attendance during the COVID-19 pandemic. Late paediatric presentations may lead to severe illness and even death. Maintaining provision of healthcare through a pandemic is essential. This qualitative study aims to identify changing care-seeking behaviours in child health during the pandemic and ascertain parental views around barriers to care.
Impact of outpatient SARS-CoV-2 infections in minority children

AUTHOR(S)
Vanessa Denny; Niva Shah; Karolina Petro (et al.)

Published: February 2021   Journal: Medicine
Data regarding COVID-19 in the adult population and hospitalized children is rapidly evolving, but little is known about children infected with severe acute respiratory syndrome coronavirus 2 who do not require hospitalization. This observational, retrospective study analyzed risk factors, demographics and clinical course of non-hospitalized patients  21 years of age with COVID-19 infection.
Cite this research | Open access | Vol.: 100 | Issue: 8 | No. of pages: 3 | Language: English | Topics: Health | Tags: child care services, child health, infectious disease, COVID-19, hospitalization
Promoting and protecting human milk and breastfeeding in a COVID-19 world

AUTHOR(S)
Diane L. Spatz; Riccardo Davanzo; Janis A. Müller (et al.)

Published: February 2021   Journal: Frontiers in Pediatrics
The global COVID-19 pandemic has put enormous stress on healthcare systems and hospital staffing. However, through all this, families will continue to become pregnant, give birth, and breastfeed. Unfortunately, care of the childbearing family has been de-prioritized during the pandemic. Additionally, many healthcare practices during the pandemic have not been positive for the childbearing family or breastfeeding. Despite recommendations from the World Health Organization to promote early, direct breastfeeding and skin to skin contact, these and other recommendations are not being followed in the clinical setting. For example, some mothers have been forced to go through labor and birth alone in some institutions whilst some hospitals have limited or no parental visitation to infants in the NICU. Furthermore, hospitals are discharging mothers and their newborns early, limiting the amount of time that families receive expert lactation care, education, and technical assistance. In addition, some hospitals have furloughed staff or transferred them to COVID-19 wards, further negatively impacting direct care for families and their newborns.
Clinical profile, hospital course and outcome of children with COVID-19

AUTHOR(S)
Karthi Nallasamy; Suresh Kumar Angurana; Muralidharan Jayashree (et al.)

Published: February 2021   Journal: The Indian Journal of Pediatrics

This paper aims to describe the epidemiological and clinical characteristics and outcome of hospitalized children with COVID-19 during the initial phase of the pandemic. This was a cross-sectional descriptive study conducted at the dedicated COVID-19 hospital of a tertiary care referral center in North India. Consecutive children aged 14 y or younger who tested positive for SARS-CoV-2 by RT-PCR from nasopharyngeal swab between 1 April 2020 and 15 July 2020 were included.

Cite this research | Open access | No. of pages: 6 | Language: English | Topics: Health | Tags: child health, COVID-19, hospitalization | Countries: India
Fever without source as the first manifestation of SARS-CoV-2 infection in infants less than 90 days old

AUTHOR(S)
Daniel Blázquez-Gamero; Cristina Epalza; José Antonio Alonso Cadenas (et al.)

Published: February 2021   Journal: European Journal of Pediatrics
Fever without source (FWS) in infants is a frequent cause of consultation at the emergency department, and the emergence of SARS-CoV-2 could affect the approach to those infants. The aim of this study is to define the clinical characteristics and rates of bacterial coinfections of infants < 90 days with FWS as the first manifestation of SARS-CoV-2 infection. This is a cross-sectional study of infants under 90 days of age with FWS and positive SARS-CoV2 PCR in nasopharyngeal swab/aspirate, attended at the emergency departments of 49 Spanish hospitals (EPICO-AEP cohort) from March 1 to June 26, 2020.
Cite this research | Open access | No. of pages: 8 | Language: English | Topics: Health | Tags: child health, early childhood, emergency aid, COVID-19, hospitalization | Countries: Spain
The association of viral load and disease severity in children with COVID‐19

AUTHOR(S)
Kubra Aykac; Burcu Ceylan Cura Yayla; Yasemin Ozsurekci (et al.)

Published: February 2021   Journal: Journal of Medical Virology
It is still not fully understood how to predict the future prognosis of patients at the diagnosis COVID‐19 due to the wide clinical range of the disease. This study aimed to evaluate whether SARS‐CoV‐2 viral load could predict the clinical course of pediatric patients. It was conducted retrospectively with medical records of pediatric patients who were tested for SARS‐CoV2 between April 12, and October 25, 2020 in the University of Health Sciences, Ankara Educating and Training Hospital and Hacettepe University Faculty of Medicine.
Cite this research | Open access | No. of pages: 19 | Language: English | Topics: Health | Tags: child health, disease transmission, COVID-19, hospitalization | Countries: Turkey
A case series of children and young people admitted to a tertiary care hospital in Germany with COVID-19

AUTHOR(S)
Jonathan Remppis; Tina Ganzenmueller; Malte Kohns Vasconcelos (et al.)

Published: February 2021   Journal: BMC Infectious Diseases
While our knowledge about COVID-19 in adults has rapidly increased, data on the course of disease and outcome in children with different comorbidities is still limited. Prospective, observational study at a tertiary care children’s hospital in southern Germany. Clinical and virology data from all paediatric patients admitted with SARS-CoV-2 infection at our hospital were prospectively assessed.
Cite this research | Open access | No. of pages: 6 | Language: English | Topics: Health | Tags: child diseases, child health, COVID-19 response, lockdown, hospitalization | Countries: Germany
Epidemiology, characteristics and outcome of children hospitalized with COVID-19 in Oman: a multicenter cohort study

AUTHOR(S)
Laila S. Al Yazidi; Zaid Al Hinai; Badriya Al Wailib (et al.)

Published: January 2021   Journal: International Journal of Infectious Diseases
To describe the epidemiology, clinical and laboratory features, and outcome of children hospitalized with coronavirus disease 2019 (COVID-19) in the Middle East. A multicenter retrospective study of children hospitalized with COVID-19 in 7 centers across Oman between February and July 2020.
Cite this research | Open access | No. of pages: 655-660 | Language: English | Topics: Health | Tags: child health, infectious disease, COVID-19, hospitalization | Countries: Oman
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UNICEF Innocenti's Children and COVID-19 Library is a database collecting research from around the world on COVID-19 and its impacts on children and adolescents.

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COVID-19 & Children: Rapid Research Response

UNICEF Innocenti is mobilizing a rapid research response in line with UNICEF’s global response to the COVID-19 crisis. The initiatives we’ve begun will provide the broad range of evidence needed to inform our work to scale up rapid assessment, develop urgent mitigating strategies in programming and advocacy, and preparation of interventions to respond to the medium and longer-term consequences of the COVID-19 crisis. The research projects cover a rapid review of evidence, education analysis, and social and economic policies.