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Children and COVID-19 Research Library

UNICEF Innocenti's curated library of COVID-19 + Children research

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31 - 45 of 145
COVID-19 infections in infants

Małgorzata Sobolewska-Pilarczyk; Maria Pokorska-Śpiewak; Anna Stachowiak (et al.)

Published: May 2022   Journal: Scientific reports
The study aimed to analyse the clinical course of COVID-19 in 300 infants, selected from 1283 children diagnosed with COVID-19 between March and December 2020, registered in the SARSTerPED multicenter database. Most of the infants were registered in October and November 2020. 44% of the group were girls, and 56% were boys. At diagnosis, the most common symptoms were fever in 77% of the children, cough in 40%, catarrh in 37%. Pneumonia associated with COVID-19 was diagnosed in 23% of the children, and gastrointestinal symptoms in 31.3%. In 52% of the infants, elevated levels of D-dimers were observed, and in 40%, elevated levels of IL-6 serum concentration were observed. During the second wave of the pandemic, 6 times more infants were hospitalized, and the children were statistically significantly younger compared to the patients during the first wave (3 months vs 8 months, p < 0.0001 respectively). During the second wave, the infants were hospitalized for longer. COVID-19 in infants usually manifests as a mild gastrointestinal or respiratory infection, but pneumonia is also observed with falls in oxygen saturation, requiring oxygen therapy.
A study of clinical profile and outcome of COVID-19 in children

M. V. Nagaraj; Chikkanna Somashekhar; Raj Muniraju Geetha Nithin (et al.)

Published: May 2022   Journal: International Journal of Contemporary Pediatrics

 COVID-19 has become a major public health crisis around the world. This study aimed at identifying the different clinical presentations of children who were tested positive for SARS-COV-2. Descriptive and prospective study of the children who were seen over the fever clinic and were admitted to the Sapthagiri institute of medical science and research centre over a period of 4 months from November 2021 to February 2022. Among the 251 children admitted to the hospital majority of them were males 52.5% and the age group of 1-5 years were highest affected 46.2%. The most common symptoms noted were fever 60.5%, followed by pain abdomen 45.8%, vomiting 43.8%, running nose 39%, cough 38%, diarrhoea 30.6%, decreased appetite 26.7% and the least common symptom was skin rash 0.3%. Children with comorbidites had higher risk of ICU admission. No deaths were noted during the study period.

Cite this research | Open access | Vol.: 9 | Issue: 5 | Language: English | Topics: Health | Tags: child health, COVID-19, health services, hospitalization, infectious disease, pandemic | Countries: India
Association between area-level material deprivation and incidence of hospitalization among children with SARS-CoV-2 in Montreal

Assil Abda; Francesca Del Giorgio; Lise Gauvin (et al.)

Published: April 2022   Journal: Paediatrics & Child Health,

Although sociodemographic factors have been linked with SARS-CoV-2 infection and hospitalizations in adults, there are little data on the association between sociodemographic characteristics and SARS-CoV-2-related hospitalization in children. The objective of this study was to determine the association between area-level material deprivation and incidence of hospitalization with SARS-CoV-2 among children. This is a retrospective cohort study of all children (0 to 17 years of age) with a PCR-confirmed SARS-CoV-2 infection March 1, 2020 through May 31, 2021 at a tertiary-care paediatric hospital, in Montreal, Canada. Data were collected through chart review and included age, sex, and postal code, allowing linkage to dissemination area-level material deprivation, measured with the Pampalon Material Deprivation Index (PMDI) quintiles. The association between PMDI quintiles and hospitalization was analyzed using Poisson regression.

Cite this research | Open access | Vol.: 27 | Issue: Supplement 1 | No. of pages: 27-32 | Language: English | Topics: Health | Tags: child health, COVID-19, health services, hospitalization, infectious disease, pandemic | Countries: Canada
Unexplained hepatitis in children after lifting COVID-19 pandemic restrictions.

Pablo Barreiro

Published: April 2022   Journal: AIDS Reviews
Since January 2022, almost 150 cases of acute hepatitis with epidemic features have been reported among children aged 1-15 years old, mostly below 5 years old. A wide range of symptoms has appeared, but a subset of these children has progressed to liver failure and required liver transplantation and at least one death has been reported already.
Cite this research | Open access | No. of pages: 3 | Language: English | Topics: Health | Tags: child health, COVID-19 response, hospitalization, lockdown, social distance | Countries: Spain
Assessment of the COVID-19 pandemic and its impact on a children's hospital: the point of view of patients and families

Maria D. Navarro-Rubio; Ana Bosque; Arian Tarbal (et al.)

Published: April 2022   Journal: Patient Experience Journal
The coronavirus pandemic has affected our health, social behavior, and quality of life. In addition to the deaths and morbidity, the crisis also affects all spheres in society. The objective of this study was to assess the perception of hospital patients and families regarding the pandemic. This is a descriptive study conducted May-July 2020 in the Sant Joan de Déu children’s hospital, Barcelona, Spain. We developed a mix-method approach. It included online semi-structured interviews and photo voice. Seventeen patients’ representatives were interviewed.
Cite this research | Open access | Vol.: 9 | Issue: 1 | No. of pages: 26-34 | Language: English | Topics: Health | Tags: child health, COVID-19 response, health care facilities, hospitalization, lockdown, social distance | Countries: Spain
impact of the covid 19 pandemic on the process of exclusive breastfeeding

Nurul Anjarwati; Veny Erlisa Irawan

Published: April 2022   Journal: Jurnal Kesehatan Mesencephalon
Impact of COVID-19 pandemic on health occurred in all age groups including pregnant women, mothers giving birth, and newborns. Breastfeeding during a pandemic requires special attention because of the short-term and long-term health implications. The purpose of this study was to explore the impact of the COVID-19 pandemic on the success of exclusive breastfeeding. The research design is qualitative with in-depth interview data collection methods on 7 participants. The sample was selected according to the inclusion criteria, namely mothers who gave birth during a pandemic and when data were collected on children aged 6-12 months in the working area of the Kepanjen Health Center, Kab. Poor. Researchers as the main instrument in the study and interview guides as a reference for questions.
Effect of COVID-19 pandemic on well child care and vaccination

Grace Onimoe; Dhanalakshmi Angappan; Marie Christianne Ravie Chandar (et al.)

Published: April 2022   Journal: Frontiers in Pediatrics

The COVID-19 virus is highly contagious primarily via aerosol transmission and has a high mortality rate. On March 13, 2020, the United States declared a national emergency in response to the COVID-19 pandemic. This study aims to enumerate the effect of the pandemic on vaccination rates during the COVID-19 lockdown and the aftermath in pediatric patients aged 6weeks-6 years. A retrospective review of medical records was performed of missed well childcare visits at MetroHealth from March 1, 2020 to June 30, 2020. The sample size of 400 children aged 6 weeks to 6 years were randomly selected. Demographic data, number of calls made to attempt, scheduled WCC, no show rates for clinic appointments, number of missed WCC, location of MH facility, insurance type, vaccination status prior to the pandemic were collected. Statistical analysis was performed with SPSS software (IBM Corp. Released 2020. IBM SPSS Statistics for Windows, Version 27.0. Armonk, NY: IBM Corp).

Changes in unintentional cannabis exposures in children 6 months to 5 years reported to United States poison centers during the first nine months of the coronavirus-19 pandemic

Thomas W. Laudone; James B. Leonard; Elizabeth Quaal Hines (et al.)

Published: April 2022   Journal: Clinical Toxicology
Almost half of exposures reported to United States (US) poison centers are exploratory ingestions in children under the age of 5 years. Pediatric cannabis exposures reported to US poison centers have risen over the last twenty years, with greater increases in the last 5 years. In 2020, the Coronavirus disease 2019 (COVID-19) pandemic resulted in widespread stay-at-home orders and subsequent changes in work, education, and daycare. This study describes the changes in pediatric cannabis exposures during the first nine months of the COVID-19 pandemic relative to the three years before the pandemic.
Outcomes and risk factors of death among hospitalized children and adolescents with obesity and COVID-19 in Brazil: An analysis of a nationwide database

Ana Cristina Simões e Silva; Mariana A. Vasconcelos; Enrico A. Colosimo (et al.)

Published: April 2022   Journal: Pediatric Obesity

Obesity is a well-recognized risk factor for critical illness and death among adult patients with SARS-CoV-2 infection. This study aimed to characterize the clinical outcomes and risk factors of death related to obesity in a cohort of hospitalized paediatric patients with COVID-19. It performed an analysis of all paediatric patients with obesity and COVID-19 registered in SIVEP-Gripe, a Brazilian nationwide surveillance database, between February 2020 and May 2021. The primary outcome was time to death, which was evaluated by using cumulative incidence function.

A study to assess the risk factors contributing to psychological stress, anxiety and depression in mothers of Covid-19 positive hospitalized children in a tertiary care hospital

Nitu Malik; Abhishek Dutta; Satyabrata Roy Chowdhary (et al.)

Published: April 2022   Journal: Journal of Paediatrics and Nursing Science
Parents of the COVID -19 positive hospitalized children are facing different psychological stresses which are affecting child’s care and well-being.
This study aims to determine the psychological stress, anxiety and depression and to identify the associated influencing factors in mothers of hospitalized COVID-19 infected children. In this cross-sectional observational study, 150 mothers of COVID-19 positive hospitalized children in a paediatric tertiary care hospital were randomly selected and studied. Data collection tool was a two part questionnaire; the first part was based on ‘Perceived stress scale-10’ and ‘Hospital anxiety and depression scale’ and the second part included stressors related to COVID-19 pandemic selected based on previous researches. The incidence of these stressors and their significance in causing stress, anxiety and depression was assessed using standard statistical methods.
Caregivers' attitudes toward COVID-19 vaccination in children and adolescents with a history of SARS-CoV-2 infection

Danilo Buonsenso; Piero Valentini; Marina Macchi (et al.)

Published: April 2022   Journal: Frontiers in Pediatrics

Limited data are available on the attitudes of caregivers toward COVID-19 vaccination in children and adolescents with a history of SARS-CoV-2 infection or Long Covid symptoms. The aim of this study was to investigate the vaccine hesitancy among caregivers of children and adolescents with a documented history of SARS-CoV-2 infection and to explore the possible associations between COVID-19 manifestations and the acceptance of the vaccine. Caregivers of children or adolescents with a microbiologically confirmed diagnosis of SARS-CoV-2 infection evaluated in two University Hospitals were interviewed.

Factors associated with hospitalization or intensive care admission in children with COVID-19 in Latin America

Eduardo López-Medina; German Camacho-Moreno; Martin E. Brizuela (et al.)

Published: April 2022   Journal: Frontiers in Pediatrics

Limited data is available from low-middle and upper-middle income countries of the factors associated with hospitalization or admission to pediatric intensive care unit (PICU) for children with COVID-19. This study aims to describe the factors associated with hospitalization or PICU admission of children with COVID-19 in Latin America. Multicenter, analytical, retrospective study of children reported from 10 different Latin American countries to the Latin-American Society of Pediatric Infectious Diseases (SLIPE-COVID) research network from June 1, 2020, and February 28, 2021. Outpatient or hospitalized children <18 years of age with COVID-19 confirmed by polymerase chain reaction or antigen detection from the nasopharynx were included. Children with multisystem inflammatory syndrome in children (MIS-C) were excluded. Associations were assessed using univariate and multivariable logistic regression models.

Effect of the COVID-19 outbreak on the incidence of other respiratory and gastrointestinal infections in children in Thai Binh, Vietnam in 2020

Quoc Tien Nguyen; Thi Loi Dao; Thi Dung Pham (et al.)

Published: April 2022   Journal: Journal of Epidemiology and Global Health

This study aims to evaluate the impact of COVID-19 mitigation measures on the total number of consultations for respiratory and gastrointestinal infections among children under 16 years in Thai Binh Pediatric Hospital, Vietnam during the year 2020. A retrospective study was carried out to review consecutive consultations occurring in children admitted from January 01, 2016 to December 31, 2020. All medical records were collected from the central numeric database of the hospital. Diagnoses were documented according to the International Classification of Diseases 10 criteria.

Children with SARS-CoV-2 infection during the novel coronaviral disease (COVID-19) outbreak in Iran: an alarming concern for severity and mortality of the disease

Setareh Mamishi; Babak Pourakbari; Mehrzad Mehdizadeh (et al.)

Published: April 2022   Journal: BMC Infectious Diseases

The rapid worldwide spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections led to public health crises globally and the number of pediatric patients with Coronavirus Disease 2019 (COVID-19) is still rising. The aim of this study was to describe the epidemiological, clinical, laboratory, and imaging features of hospitalized patients with COVID-19 at an Iranian referral pediatrics hospital and to compare these parameters between hospitalized patients with and without severe disease, multisystem inflammatory syndrome in children (MIS-C) and children with acute COVID-19, as well as deceased and discharged cases. This study included hospitalized children and adolescents (≤ 18 years) with suspected COVID-19 who had positive results for SARS-CoV-2.

Trends in pediatric hospitalizations and mortality during the Covid-19 pandemic in an urban setting in Cameroon

Andreas Chiabi; Mfie Nji Forgwei; Marie Bissong (et al.)

Published: April 2022   Journal: Journal of Tropical Pediatrics

The first case of coronavirus disease 2019 (COVID-19) in Cameroon was recorded in March 2020. In response to the pandemic, most countries like Cameroon instituted a number of control measures to curb its spread accross the country. These COVID-19 control measures added to the fear of this disease within the population may have led to other detrimental health effects like: the pattern of hospitalizations and hospital outcomes. This is a cross-sectional study with data from in-patient admission records of children admitted to the pediatric ward of the Regional Hospital Bamenda over a 24 months period (1st of March 2019 to the 28th of February 2021). The pre-pandemic period in Cameroon (that is, the first 12 months, from March 2019 to February 2020) and the pandemic period (that is, the last 12 months, from March 2020 to February 2021) were compared.

Cite this research | Open access | Vol.: 68 | Issue: 3 | No. of pages: 8 | Language: English | Topics: Health | Tags: child health, child mortality, COVID-19, hospitalization, infectious disease, pandemic, urban areas | Countries: Cameroon
31 - 45 of 145

UNICEF Innocenti's Children and COVID-19 Library is a database collecting research from around the world on COVID-19 and its impacts on children and adolescents.


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