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Children and COVID-19 Research Library

UNICEF Innocenti's curated library of COVID-19 + Children research

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76 - 90 of 131
Parent and adolescent perspectives on the impact of COVID on the care of seriously ill children

AUTHOR(S)
Leah J. Beight; Gabrielle Helton; Madeline Avery (et al.)

Published: July 2021   Journal: Journal of Pain and Symptom Management

Few studies have explored the impact of the Coronavirus Pandemic (COVID-19) on the care of seriously ill children which may be especially affected due to the child's vulnerability, complexity of care, and high reliance on hospital-based care. This study aims to explore parental and adolescent perspectives on the impact of COVID-19 on care of seriously children.

Impact of nonpharmacological COVID-19 interventions in hospitalizations for childhood pneumonia in Brazil

AUTHOR(S)
Frederico Friedrich; Laura de Castro e Garcia; Lucas Montiel Petry (et al.)

Published: July 2021   Journal: Pediatric Pulmonology

The knowledge about the impact of the nonpharmacological measures to control the COVID-19 pandemic can give insight into ways in which they can also be applied for other respiratory diseases. To assess the impact of containment measures of the COVID-19 pandemic on pneumonia hospitalizations in children from 0 to 14 years of age in Brazil. Data from hospital admissions for pneumonia were obtained from the Department of Informatics of Brazilian Public Health System database in the period of 2015–2020 and analyzed by macroregions and age groups. To evaluate the effect of containment measures, on the incidence of pneumonia, the absolute reduction and relative reduction were calculated by analyzing the subsets 2015-2019 vs. 2020.

COVID-19 in children: where do we stand?

AUTHOR(S)
Georgia B. Nikolopoulou; Helena C. Maltezou

Published: July 2021   Journal: Archives of Medical Research
From the beginning of the coronavirus disease 2019 (COVID-19) pandemic it became evident that children infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remain mostly asymptomatic or mildly symptomatic. This study reviewed the epidemiologic and clinical features of children with SARS-CoV-2 infection. The true prevalence of asymptomatic SARS-CoV-2 infection is most likely underestimated, as asymptomatic children are less frequently tested. Serologic surveys indicate that half of children tested positive for SARS-CoV-2 report no symptoms. Anosmia/ageusia is not frequent in children but it is the strongest predictor of a positive SARS-CoV-2 test. In general, children with COVID-19 are at lower risk of hospitalization and life-threatening complications. Nevertheless, cases of severe disease or a post-infectious multisystem hyperinflammatory syndrome named multisystem inflammatory syndrome in children (MIS-C) have been described. Rarely children with severe COVID-19 develop neurologic complications.
Evaluation of changes in pediatric healthcare activity during the Covid-19 state of alarm in the Canary Islands

AUTHOR(S)
Valewska G. Wallis Gómez; María Hernández Apolinario; Pedro Saavedra Santana (et al.)

Published: July 2021   Journal: Public Health in Practice

During the SARS-CoV-2 state of alarm (SoA), a 30–70% reduction was observed in the number of visits to Pediatric Emergency Departments (ED), as well as frequent delay in diagnosis or difficulty accessing healthcare services. This study evaluates modifications observed in pediatric healthcare activity during the SoA. This is a descriptive retrospective observational study of the hospital pediatric activity.

Neurological manifestations of SARS-CoV-2 infection in hospitalised children and adolescents in the UK: a prospective national cohort study

AUTHOR(S)
Stephen T. J. Ray; Omar Abdel-Mannan; Mario Sa (et al.)

Published: July 2021   Journal: The Lancet Child & Adolescent Health
The spectrum of neurological and psychiatric complications associated with paediatric SARS-CoV-2 infection is poorly understood. This study aimed to analyse the range and prevalence of these complications in hospitalised children and adolescents. It did a prospective national cohort study in the UK using an online network of secure rapid-response notification portals established by the CoroNerve study group. Paediatric neurologists were invited to notify any children and adolescents (age <18 years) admitted to hospital with neurological or psychiatric disorders in whom they considered SARS-CoV-2 infection to be relevant to the presentation. Patients were excluded if they did not have a neurological consultation or neurological investigations or both, or did not meet the definition for confirmed SARS-CoV-2 infection (a positive PCR of respiratory or spinal fluid samples, serology for anti-SARS-CoV-2 IgG, or both), or the Royal College of Paediatrics and Child Health criteria for paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS). Individuals were classified as having either a primary neurological disorder associated with COVID-19 (COVID-19 neurology group) or PIMS-TS with neurological features (PIMS-TS neurology group). The denominator of all hospitalised children and adolescents with COVID-19 was collated from National Health Service England data.
Association between race and COVID-19 outcomes among 2.6 million children in England

AUTHOR(S)
Defne Saatci; Tom A. Ranger; Cesar Garriga (et al.)

Published: June 2021   Journal: JAMA Pediatrics

Although children mainly experience mild COVID-19 disease, hospitalization rates are increasing, with limited understanding of underlying factors. There is an established association between race and severe COVID-19 outcomes in adults in England; however, whether a similar association exists in children is unclear. This article aims to investigate the association between race and childhood COVID-19 testing and hospital outcomes.

Impact and projections of the COVID-19 epidemic on attendance and routine vaccinations at a pediatric referral hospital in Cameroon

AUTHOR(S)
D. Chelo; F. Nguefack; D. Enyama (et al.)

Published: June 2021   Journal: Archives de Pédiatrie

At the beginning of March 2020, Cameroon experienced its first cases of infection with the new coronavirus (SARS-COV-2). Very quickly, there was a drop in the rate of hospital attendance. The purpose of this study was to observe the variations in the uptake of pediatric consultations and vaccinations in a pediatric hospital. A descriptive and retrospective cross-sectional study was carried out using consultation and vaccination statistics from a pediatric hospital in the city of Yaoundé, political capital of Cameroon, from January 2016 to May 2020.

Clinical characteristics and risk factors for death among hospitalised children and adolescents with COVID-19 in Brazil: an analysis of a nationwide database

AUTHOR(S)
Eduardo A. Oliveira; Enrico A. Colosimo; Ana Cristina Simões e Silva (et al.)

Published: June 2021   Journal: The Lancet Child & Adolescent Health
COVID-19 is usually less severe and has lower case fatality in children than in adults. This study aimed to characterise the clinical features of children and adolescents hospitalised with laboratory-confirmed SARS-CoV-2 infection and to evaluate the risk factors for COVID-19-related death in this population. It did an analysis of all patients younger than 20 years who had quantitative RT-PCR-confirmed COVID-19 and were registered in the Influenza Epidemiological Surveillance Information System (SIVEP-Gripe, a nationwide surveillance database of patients admitted to hospital with severe acute respiratory disease in Brazil), between Feb 16, 2020, and Jan 9, 2021. The primary outcome was time to recovery (discharge) or in-hospital death, evaluated by competing risks analysis using the cumulative incidence function.
Cite this research | Open access | No. of pages: 10 | Language: English | Topics: Health | Tags: child health, COVID-19, disease transmission, hospitalization | Countries: Brazil
Newborns of COVID-19 mothers: short-term outcomes of colocating and breastfeeding from the pandemic’s epicenter

AUTHOR(S)
Uday P. Patil; Sheela Maru; Parvathy Krishnan (et al.)

Published: June 2021
The United States of America has been severely affected by the COVID-19 pandemic during the spring of 2020. The largely immigrant and densely populated neighborhoods of Queens, NY, served by a large public hospital, Elmhurst Hospital Center (NYC H+H/Elmhurst), have emerged as one of the hardest-hit areas in the country. Newborns are at high risk of acquiring severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from their infected mothers who delivered during this period; however, data remains limited. This article aims to describe the unique experience from our Baby Friendly hospital at the epicenter of the COVID-19 pandemic.
Consequences of early separation of maternal-newborn dyad in neonates born to SARS-CoV-2 positive mothers: an observational study

AUTHOR(S)
Maria Giulia Conti; Fabio Natale; Ilaria Stolfi (et al.)

Published: May 2021   Journal: International Journal of Environmental Research and Public Health

As the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection continues its spread all over the world, data on perinatal management of the maternal-infant dyad are urgent. This observational study aimed to describe the effects of the early separation of the maternal-infant dyad, in case of maternal SARS-CoV-2 infection. It reported the medical records for 37 neonates born to 37 SARS-CoV-2 positive mothers in a setting of separation of the dyad after birth. Data on neonatal infection, clinical condition, and breastfeeding rate were recorded until the first month of life. No maternal deaths were recorded; 37.8% of women had at least one pregnancy-related complication.

The impact of personal protective equipment and social distancing on communication and relation between nurses, caregivers and children: a descriptive qualitative study in a maternal and child health hospital

AUTHOR(S)
Giada Ferrari; Raffaella Dobrina; Sara Buchini (et al.)

Published: May 2021   Journal: Journal of Clinical Nursing

The main objective was to explore the impact of personal protective equipment and social distancing on nurses, caregivers and children's communication and relationship in a maternal and child health hospital. The spread of COVID-19 pandemic made it necessary to apply infection prevention and control measures, including interpersonal distancing and the use of personal protective equipment. These measures may impact communication and relationship between nurses, patients and caregivers especially in a complex environment, such as a paediatric setting.

Bridging the gap: exploring the impact of hospital isolation on peer relationships among children and adolescents with a malignant brain tumor

AUTHOR(S)
Jami‑Leigh Sawyer; Faye Mishna; Eric Boufet (et al.)

Published: May 2021   Journal: Child and Adolescent Social Work Journal
Children and adolescents with complex medical conditions are often uprooted from their environments and isolated in hospital while undergoing treatment. Little is known about how they perceive this isolation and its subsequent impact on their relationships with peers, both during and after isolation for treatment. This study describes the experience of hospital isolation from the perspectives of children and adolescents with a malignant brain tumor. The use and impact of information and communication technologies (ICT) as a possible bridge for contact is also explored. Following a qualitative approach utilizing interpretive phenomenological analysis, in-depth interviews were conducted with eight youth participants who had undergone treatment for medulloblastoma. Data analysis generated three main themes: (1) transforming children and relationships, (2) hospitalization in a digital world, and (3) ICTs as a promising bridge back to school.
Changes in infection-related hospitalizations in children following pandemic restrictions: an interrupted time-series analysis of total population data

AUTHOR(S)
Isobel M. F. Todd; Jessica E. Miller; Stacey L. Rowe

Published: May 2021   Journal: International Journal of Epidemiology
Infectious diseases are a leading cause of hospitalization during childhood. The various mitigation strategies implemented to control the coronavirus disease (COVID-19) pandemic could have additional, unintended benefits for limiting the spread of other infectious diseases and their associated burden on the health care system.
The impact of the COVID-19 pandemic on nighttime room entries and sleep disruptions for pediatric patients

AUTHOR(S)
Joseph M. Riehm; Vineet M. Arora; Swetha Tatineni (et al.)

Published: May 2021   Journal: Sleep Medicine
Sleep is critical to recovery, but inpatient sleep is often disrupted. During the COVID-19 pandemic, social distancing efforts to minimize spread may have improved hospitalized children’s sleep by decreasing unnecessary overnight disruptions. This study aimed to describe the impact of these efforts on pediatric inpatient sleep using objective and subjective metrics.
What are the risk factors for admission to the pediatric intensive unit among pediatric patients with COVID-19?

AUTHOR(S)
Susanna Esposito; Fabio Caramelli; Nicola Principi

Published: May 2021   Journal: Italian Journal of Pediatrics
Although with exceptions, evidence seems to indicate that children have lower susceptibility than adults to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. When infected, children generally remain asymptomatic or develop mild disease. A small number of pediatric cases required admission to the pediatric intensive care unit (PICU), respiratory support with a mechanical ventilation and additional life-saving interventions. Even if rarely, death can occur. Aim of this manuscript is to highlight the risk factors associated with severe outcome among pediatric patients with COVID-19.
76 - 90 of 131

UNICEF Innocenti's Children and COVID-19 Library is a database collecting research from around the world on COVID-19 and its impacts on children and adolescents.

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COVID-19 & Children: Rapid Research Response

UNICEF Innocenti is mobilizing a rapid research response in line with UNICEF’s global response to the COVID-19 crisis. The initiatives we’ve begun will provide the broad range of evidence needed to inform our work to scale up rapid assessment, develop urgent mitigating strategies in programming and advocacy, and preparation of interventions to respond to the medium and longer-term consequences of the COVID-19 crisis. The research projects cover a rapid review of evidence, education analysis, and social and economic policies.