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Christine A. Limbers; Rachel Thompson
The current study assessed maternal attitudes and intention about the COVID-19 vaccine for children ages 5 to 11 years since the onset of the Delta variant and examined if the Delta variant changed maternal perceptions about COVID-19 vaccination and COVID-19 precautions for children. Participants were 821 mothers (mean age = 40.11 years; 84.3% White) from the United States who had at least one child ages 5 to 11 years old. They were recruited online and completed questionnaires on Qualtrics about their youngest child ages 5 to 11 years. The majority of mothers (n = 595; 72.6%) reported they were very likely to have their child vaccinated for COVID-19 once a vaccine is available for children. After controlling for maternal and child factors, maternal trust in the COVID-19 vaccine development and approval process (Odds Ratios = 35.07; p <0.001), trust in the child’s physician (Odds Ratios = 1.65; p <0.01), and trust in the local public health department (Odds Ratios = 1.87; p <0.05) were associated with maternal likelihood of having one’s child vaccinated for COVID-19.
Alice Morissette; Gabrielle Lefebvre; Claude Bacque-Dion (et al.)
This is the first position paper to be published by WHO on the behavioural and social drivers (BeSD) of vaccine uptake. It summarizes the development of new tools and indicators to assess the BeSD of vaccine uptake for childhood and COVID-19 vaccination, enabling decision-makers on immunization policy, programme managers, and partners to address under-vaccination through an enhanced understanding of the underlying causes. This paper also reports the main findings of a scoping review that examined existing systematic reviews and meta-analyses on interventions to improve vaccine uptake – a first step towards understanding which interventions work to increase vaccine uptake, for whom, and in what settings. Finally, this paper makes recommendations for using the new tools and the resulting data to prioritize local interventions, and concludes with future research directions.
Don E. Willis; Mario Schootman; Sumit K. Shah (et al.)
Sibel Baktır Altuntaş; Gizem Kara Elitok
Naïm Ouldali; Haleh Bagheri; Francesco Salvo (et al.)
Multisystem inflammatory syndrome in children (MIS-C) is the most severe clinical entity associated with pediatric SARS-CoV-2 infection with a putative role of the spike protein into the immune system activation. Whether COVID-19 mRNA vaccine can induce this complication in children is unknown. This study aimed to assess the risk of hyper-inflammatory syndrome following COVID-19 mRNA vaccine in children. It conducted a post-authorization national population-based surveillance using the French enhanced pharmacovigilance surveillance system for COVID-19 vaccines. All cases of suspected hyper-inflammatory syndrome following COVID-19 mRNA vaccine in 12–17-year-old children between June 15th, 2021 and January 1st, 2022, were reported. Cases were reviewed according to WHO criteria for MIS-C. The reporting rate of this syndrome was compared to the MIS-C rate per 1,000,000 12–17-year-old children infected by SARS-CoV-2.
Remiya Mohan; Vandna Pandey; Ashok Kumar (et al.)
The coronavirus disease 2019 (COVID-19) pandemic has claimed millions of lives worldwide. India also launched a COVID-19 vaccination drive, and clinical trials for a pediatric COVID-19 vaccine are in development. The study aims to assess the acceptance and attitude of parents regarding the COVID-19 vaccine for children in India. The study also aims to find the association between selected demographic variables and acceptance and attitudes in parents regarding the COVID-19 vaccine for children.
Sultan F. Alhazza; Ali M. Altalhi; Khaled M. Alamri (et al.)
Parents' hesitancy (PH) toward childhood vaccination, including the vaccine of coronavirus disease (COVID-19), is one of the top public health threats. We aim to assess the PH toward children COVID-19 vaccination as compared to PH toward children routine vaccination among the residents of Saudi Arabia. Before the official approval of children's COVID-19 vaccination in the country, a cross-sectional study using an electronically distributed survey was performed. Responses from parents of children younger than 18 years of age were accepted. The Oxford COVID-19 vaccine hesitancy scale (OC19-VHS) and the routine vaccination hesitancy scale (R-VHS) were used. Parents were classified as hesitant, non-hesitant, and unsure.
Carlo Pietrasanta; Andrea Ronchi; Beatrice Letizia Crippa (et al.)
Grace Onimoe; Dhanalakshmi Angappan; Marie Christianne Ravie Chandar (et al.)
The COVID-19 virus is highly contagious primarily via aerosol transmission and has a high mortality rate. On March 13, 2020, the United States declared a national emergency in response to the COVID-19 pandemic. This study aims to enumerate the effect of the pandemic on vaccination rates during the COVID-19 lockdown and the aftermath in pediatric patients aged 6weeks-6 years. A retrospective review of medical records was performed of missed well childcare visits at MetroHealth from March 1, 2020 to June 30, 2020. The sample size of 400 children aged 6 weeks to 6 years were randomly selected. Demographic data, number of calls made to attempt, scheduled WCC, no show rates for clinic appointments, number of missed WCC, location of MH facility, insurance type, vaccination status prior to the pandemic were collected. Statistical analysis was performed with SPSS software (IBM Corp. Released 2020. IBM SPSS Statistics for Windows, Version 27.0. Armonk, NY: IBM Corp).
Eva Yi Hung Lau; Jian-Bin Li; Derwin King Chung Chan
Vicki Myers; Mor Saban; Rachel Wilf-Miron
Children under 12 are now the largest unvaccinated group. Following FDA approval, vaccination of 5–11 year olds is now being encouraged in some countries. We present data on child COVID-related morbidity in Israel and discuss the complexities surrounding vaccinating children aged 5–11. Data were obtained from Israel’s open COVID database regarding new confirmed daily COVID-19 cases, severe hospitalized cases and deaths by age group in Israel from February 2020-November 2021, as well as vaccination rate and adverse events following vaccination
Yuxuan Du; Long Chen; Yuan Shi
As the epidemic progresses, universal vaccination against COVID-19 has been the trend, but there are still some doubts about the efficacy and safety of COVID-19 vaccines in adolescents, children, and even infants. This study aims to evaluate the safety, immunogenicity, and efficacy of COVID-19 vaccines in the population aged 0–17 years. A comprehensive search for relevant randomized controlled trials (RCTs) was conducted in PubMed, Embase, and the Cochrane Library from inception to November 9, 2021. All data were pooled by RevMan 5.3 statistical software, with risk ratio (RR) and its 95% confidence interval as the effect measure. This study protocol was registered on PROSPERO (CRD42021290205).
Danilo Buonsenso; Piero Valentini; Marina Macchi (et al.)
Limited data are available on the attitudes of caregivers toward COVID-19 vaccination in children and adolescents with a history of SARS-CoV-2 infection or Long Covid symptoms. The aim of this study was to investigate the vaccine hesitancy among caregivers of children and adolescents with a documented history of SARS-CoV-2 infection and to explore the possible associations between COVID-19 manifestations and the acceptance of the vaccine. Caregivers of children or adolescents with a microbiologically confirmed diagnosis of SARS-CoV-2 infection evaluated in two University Hospitals were interviewed.
UNICEF Innocenti's Children and COVID-19 Library is a database collecting research from around the world on COVID-19 and its impacts on children and adolescents.
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