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Children and COVID-19 Research Library

UNDER DEVELOPMENT UNICEF Innocenti's curated library of COVID-19 + Children research

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16 - 30 of 112
Early impact of school closure and social distancing for COVID-19 on the number of inpatients with childhood non-COVID-19 acute infections in Japan

AUTHOR(S)
Kenji Kishimoto; Seiko Bun; Jung-ho Shin (et al.)

Published: March 2021   Journal: European Journal of Pediatrics
Many countries have implemented school closures as part of social distancing measures intended to control the spread of coronavirus disease 2019 (COVID-19). The aim of this study was to assess the early impact of nationwide school closure (March–May 2020) and social distancing for COVID-19 on the number of inpatients with major childhood infectious diseases in Japan.
Social determinants of health and Coronavirus disease 2019 in pregnancy

AUTHOR(S)
Lakha Prasannan; Burton Rochelson; Weiwei Shan (et al.)

Published: March 2021   Journal: American Journal of Obstetrics & Gynecology
The social and physical environments in which people live affect the emergence, prevalence and severity of both infectious and non-infectious diseases. There is limited data on how such social determinants of health (SDH), including neighborhood socioeconomic conditions, affect the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and severity of coronavirus disease 2019 (COVID-19) during pregnancy. This paper's objective was to determine how SDH are associated with SARS-CoV-2 infection and the severity of COVID-19 illness in hospitalized pregnant patients in New York during the global COVID-19 pandemic.
Screening of COVID-19 in outpatient children with cancer or solid organ transplantation: preliminary report

AUTHOR(S)
Thaís Lira Cleto-Yamane; Gustavo Rodrigues-Santos; Maria Clara de Magalhães-Barbosa

Published: March 2021   Journal: European Journal of Pediatrics
Clinical presentation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in pediatric immunosuppressed patients is unknown. Emerging data describe a milder or asymptomatic course in children compared with adults in this scenario. This paper presents the seroprevalence and clinical features of coronavirus disease 2019 in a prospective cohort of 114 immunosuppressed children and adolescents from three groups: kidney transplantation, liver transplantation, and cancer patients.
A comprehensive analysis of maternal and newborn disease and related control for COVID-19

AUTHOR(S)
Nevio Cimolai

Published: March 2021   Journal: SN Comprehensive Clinical Medicine
The maternal-fetal/newborn unit is established at risk for COVID-19 infection. This narrative review summarizes the contemporary and cumulative publications which detail maternal infection, antenatal and newborn infections, and maternal/fetal/newborn management and prevention. There is a wide spectrum of maternal disease, but the potential for severe disease albeit in a minority is confirmed. COVID-19 carries risk for preterm delivery. Pregnant females can suffer multisystem disease, and co-morbidities play a significant role in risk. Congenital infection has been supported by several anecdotal reports, but strong confirmatory data are few. No typical congenital dysmorphisms are evident. Nevertheless, placental vascular compromise must be considered a risk for the fetus during advanced maternal infections. Clinical manifestations of newborn infection have been mild to moderate and relatively uncommon.
Clustering and longitudinal change in SARS-CoV-2 seroprevalence in school children in the canton of Zurich, Switzerland: prospective cohort study of 55 schools

AUTHOR(S)
Agne Ulyte; Thomas Radtke; Irene A. Abela

Published: March 2021   Journal: BMJ
This prospective cohort study aims to examine longitudinal changes in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence and to determine the clustering of children who were seropositive within school classes in the canton of Zurich, Switzerland from June to November 2020.
Association between living with children and outcomes from covid-19: OpenSAFELY cohort study of 12 million adults in England

AUTHOR(S)
Harriet Forbes; Caroline E. Morton; Seb Bacon (et al.)

Published: March 2021
This  population based cohort study, on behalf of NHS England, aimed to investigate whether risk of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and outcomes of coronavirus disease 2019 (covid-19) differed between adults living with and without children during the first two waves of the UK pandemic.
Increased risk of rhinovirus infection in children during the coronavirus disease‐19 pandemic

AUTHOR(S)
Emi Takashita; Chiharu Kawakami ; Tomoko Momoki (et al.)

Published: March 2021   Journal: Influenza and Other Respiratory Viruses

Coronavirus disease (COVID‐19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), was first detected in Japan in January 2020 and has spread throughout the country. Previous studies have reported that viral interference among influenza virus, rhinovirus, and other respiratory viruses can affect viral infections at the host and population level. To investigate the impact of COVID‐19 on influenza and other respiratory virus infections, this study analyzed clinical specimens collected from 2244 patients in Japan with respiratory diseases between January 2018 and September 2020.

COVID-19 management in pediatrics

AUTHOR(S)
Magalie L. Alcindor; FitzGerald Alcindor; Kristy E. Richard

Published: March 2021   Journal: The Journal for Nurse Practitioners
Coronavirus disease 2019 (COVID-19) is a deadly global pandemic, with scientific efforts improving our understanding of this novel coronavirus. No proven disease-specific therapies exist, although 2 vaccines have been recently approved by the United States Food and Drug Administration under emergency use authori-zation, and several others are in development or phase III clinical trial testing. COVID-19 presents in greater severity in the medically fragile, obese, elderly, and socially disadvantaged, and children in general are less affected. All children are at risk, but those with comorbidities and neonates are more susceptible. The multisystem inflammatory syndrome is a severe version which can present in any child with a recent COVID-19 infection. The face of the pandemic has been changing in the last few months, with recent increasing cases,virus mutations, and onset of vaccination. This article provides COVID-19 management for children and adolescents and implications for nursing and advanced practice providers.
SARS-CoV-2 infection and transmission in primary schools in England in June–December, 2020 (sKIDs): an active, prospective surveillance study

AUTHOR(S)
Shamez N. Ladhani; Frances Baawuah; Joanne Beckmann (et al.)

Published: March 2021   Journal: The Lancet Child & Adolescent Health
Little is known about the risk of SARS-CoV-2 infection and transmission in educational settings. Public Health England initiated a study, COVID-19 Surveillance in School KIDs (sKIDs), in primary schools when they partially reopened from June 1, 2020, after the first national lockdown in England to estimate the incidence of symptomatic and asymptomatic SARS-CoV-2 infection, seroprevalence, and seroconversion in staff and students.
Prevalence of RT-qPCR-detected SARS-CoV-2 infection at schools: first results from the Austrian School-SARS-CoV-2 prospective cohort study

AUTHOR(S)
Peter Willeit; Robert Krause; Bernd Lamprecht

Published: March 2021   Journal: The Lancet Regional Health - Europe Log inRegister RESEAR
The role of schools in the SARS-CoV-2 pandemic is much debated. We aimed to quantify reliably the prevalence of SARS-CoV-2 infections at schools detected with reverse-transcription quantitative polymerase-chain-reaction (RT-qPCR). This nationwide prospective cohort study monitors a representative sample of pupils (grade 1–8) and teachers at Austrian schools throughout the school year 2020/2021. It repeatedly tested participants for SARS-CoV-2 infection using a gargling solution and RT-qPCR and herein reported on the first two rounds of examinations.
Cite this research | Open access | No. of pages: 9 | Language: English | Topics: Health | Tags: COVID-19, disease transmission, infectious disease, school attendance | Countries: Austria
SARS-CoV-2 prevalence associated to low socioeconomic status and overcrowding in an LMIC megacity: a population-based seroepidemiological survey in Lima, Peru

AUTHOR(S)
Mary F. Reyes-Vega; M.Gabriela Soto-Cabezas; Fany Cardenas (et al.)

Published: March 2021   Journal: EClinicalMedicine
Worldwide, Peru has one of the highest infection fatality rates of COVID-19, and its capital city, Lima, accumulates roughly 50% of diagnosed cases. Despite surveillance efforts to assess the extent of the pandemic, reported cases and deaths only capture a fraction of its impact due to COVID-19′s broad clinical spectrum. This study aimed to estimate the seroprevalence of SARS-CoV-2 in Lima, stratified by age, sex, region, socioeconomic status (SES), overcrowding, and symptoms.
Household SARS-CoV-2 transmission and children: a network prospective study

AUTHOR(S)
Antoni Soriano-Arandes; Anna Gatell; Pepe Serrano (et al.)

Published: March 2021   Journal: Clinical Infectious Diseases
The role of children in household transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remains uncertain. Here, we describe the epidemiological and clinical characteristics of children with COVID-19 in Catalonia (Spain) and investigate the dynamics of household transmission. Prospective, observational, multicenter study performed during summer and school periods (1 July31 October, 2020), in which epidemiological and clinical features, and viral transmission dynamics were analyzed in COVID-19 patients <16 years. A pediatric index case was established when a child was the first individual infected within a household. Secondary cases were defined when another household member tested positive for SARS-CoV-2 before the child. The secondary attack rate (SAR) was calculated, and logistic regression was used to assess associations between transmission risk factors and SARS-CoV-2 infections.
Cite this research | Open access | No. of pages: 32 | Language: English | Topics: Health | Tags: COVID-19, disease transmission, family, household, infectious disease | Countries: Spain
COVID-19 in youth soccer during summer 2020

AUTHOR(S)
Andrew M. Watson; Kristin Haraldsdottir; Kevin Biese

Published: March 2021   Journal: Journal of Athletic Training

As sports reinitiate around the country, the incidence of COVID-19 among youth soccer athletes remains unknown. This paper aims to determine the incidence of COVID-19 among youth soccer athletes and the risk mitigation practices utilized by youth soccer organizations.

Cite this research | Open access | Vol.: 65 | Issue: 3 | No. of pages: 22 | Language: English | Topics: Health | Tags: adolescents, COVID-19 response, infectious disease, physical activity, youth
Effectiveness of the 2019–2020 influenza vaccine and the effect of prior influenza infection and vaccination in children during the first influenza season overlapping with the COVID-19 epidemic

AUTHOR(S)
Soichiro Ando

Published: March 2021   Journal: Journal of Nippon Medical School

The behavioral changes among Japanese, along with the coronavirus disease 2019 (COVID-19) epidemic, may affect the seasonal influenza epidemic in Japan and change the influenza vaccine effectiveness (VE). Influenza VE in children was estimated in the first influenza season (2019/20) overlapping with the COVID-19 epidemic by conducting a single-center, test-negative case-control (TNCC) study. Effects of prior influenza infection and vaccination in children were assessed for the 2019–2020 season.

Comparison of clinical severity and epidemiological spectrum between coronavirus disease 2019 and influenza in children

AUTHOR(S)
Maria Pokorska‑Śpiewak; Ewa Talarek; Jolanta Popielska (et al.)

Published: March 2021   Journal: Scientific Reports
Data on the novel coronavirus disease 2019 (COVID-19) in children are limited, and studies from Europe are scarce. This paper analyzed the clinical severity and epidemiologic aspects of COVID-19 in consecutive children aged 0–18 years, referred with a suspicion of COVID-19 between February 1, and April 15, 2020. RT-PCR on a nasopharyngeal swab was used to confirm COVID-19. 319 children met the criteria of a suspected case.
16 - 30 of 112

UNICEF Innocenti's Children and COVID-19 Library is a database collecting research from around the world on COVID-19 and its impacts on children and adolescents.

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COVID-19 & Children: Rapid Research Response

UNICEF Innocenti is mobilizing a rapid research response in line with UNICEF’s global response to the COVID-19 crisis. The initiatives we’ve begun will provide the broad range of evidence needed to inform our work to scale up rapid assessment, develop urgent mitigating strategies in programming and advocacy, and preparation of interventions to respond to the medium and longer-term consequences of the COVID-19 crisis. The research projects cover a rapid review of evidence, education analysis, and social and economic policies.