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Children and COVID-19 Research Library

UNICEF Innocenti's curated library of COVID-19 + Children research

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Adverse perinatal outcomes in a large US birth cohort during the COVID-19 pandemic: adverse perinatal outcomes during COVID-19

AUTHOR(S)
Ethan A. Litman; Ying Yin; Stuart J. Nelson

Published: February 2022   Journal: American Journal of Obstetrics & Gynecology MFM

This study aimed to investigate whether coronavirus disease 2019 (COVID-19) is associated with adverse perinatal outcomes in a large national dataset and to examine rates of adverse outcomes during the pandemic compared to pre-pandemic period. This observational cohort study included 683,905 patients, between the ages of 12-50, hospitalized for childbirth and abortion between January 1, 2019 and May 31, 2021. During the pre-pandemic period, 271,444 women were hospitalized for childbirth. During the pandemic, 308,532 women were hospitalized for childbirth and 2,708 had COVID-19. Associations between COVID-19 and in-hospital adverse perinatal outcomes were examined using propensity score-adjusted logistic regression.

Exploring the lived experiences of pregnant women and community health care providers during the pandemic of COVID-19 in Bangladesh through a phenomenological analysis

AUTHOR(S)
Sadika Akhter; Feroza Akhter Kumkum; Farzana Bashar (et al.)

Published: December 2021   Journal: BMC Pregnancy and Childbirth

Like many countries, the government of Bangladesh also imposed stay-at-home orders to restrict the spread of severe acute respiratory syndrome coronavirus-2 (COVID-19) in March, 2020. Epidemiological studies were undertaken to estimate the early possible unforeseen effects on maternal mortality due to the disruption of services during the lockdown. Little is known about the constraints faced by the pregnant women and community health workers in accessing and providing basic obstetric services during the pandemic in the country. This study was conducted to explore the lived experience of pregnant women and community health care providers from two southern districts of Bangladesh during the pandemic of COVID-19. The study participants were recruited through purposive sampling and non-structured in-depth interviews were conducted. Data was collected over the telephone from April to June, 2020. The data collected was analyzed through a phenomenological approach.

Maternal mortality during the COVID-19 pandemic in Mexico: a preliminary analysis during the first year

AUTHOR(S)
Nina Mendez-Dominguez; Karen Santos-Zaldívar; Salvador Gomez-Carro (et al.)

Published: July 2021   Journal: BMC Public Health

In Mexico, the COVID-19 pandemic led to preventative measures such as confinement and social interaction limitations that paradoxically may have aggravated healthcare access disparities for pregnant women and accentuated health system weaknesses addressing high-risk patients’ pregnancies. This study's objective is to estimate the maternal mortality ratio in 1 year and analyze the clinical course of pregnant women hospitalized due to acute respiratory distress syndrome and COVID-19. A retrospective surveillance study of the national maternal mortality was performed from February 2020–February 2021 in Mexico related to COVID-19 cases in pregnant women, including their outcomes. Comparisons were made between patients who died and those who survived to identify prognostic factors and underlying health conditions distribution.

Maternal and perinatal outcomes of pregnant women with SARS-CoV-2 infection at the time of birth in England: national cohort study

AUTHOR(S)
Ipek Gurol-Urganci; Jennifer E. Jardine; Fran Carroll (et al.)

Published: May 2021   Journal: American Journal of Obstetrics and Gynecology

The aim of this study was to determine the association between SARS-CoV-2 infection at the time of birth and maternal and perinatal outcomes. This is a population-based cohort study in England. The inclusion criteria were women with a recorded singleton birth between 29th May 2020 and 31st January 2021 in a national database of hospital admissions. Maternal and perinatal outcomes were compared between pregnant women with a laboratory-confirmed SARS-CoV-2 infection recorded in the birth episode and those without.

COVID-19 preparedness—a survey among neonatal care providers in low- and middle-income countries

AUTHOR(S)
Claus Klingenberg; Sahil K. Tembulkar; Anna Lavizzari (et al.)

Published: May 2021   Journal: Journal of Perinatology volume
This study aims to evaluate COVID-19 pandemic preparedness, available resources, and guidelines for neonatal care delivery among neonatal health care providers in low- and middle-income countries (LMICs) across all continents. Cross-sectional, web-based survey administered between May and June, 2020.
Decrease in admissions and change in the diagnostic landscape in a newborn care unit in Northern Ghana during the COVID-19 pandemic

AUTHOR(S)
Alhassan Abdul-Mumin; Cesia Cotache-Condor; Kingsley Appiah Bimpong (et al.)

Published: March 2021   Journal: Frontiers in Pediatrics
The coronavirus disease (COVID-19) has spread worldwide with an increasing number of patients, including pregnant women and neonates. This study aims to evaluate morbidity and mortality in the COVID-19 era compared to the preceding year in the Neonatal Intensive Care Unit (NICU) at Tamale Teaching Hospital, Ghana. This is a cross-sectional study carried out on neonates admitted to NICU between March 1st to August 31st, 2019 (pre-COVID-19 era) and March 1st to August 31st, 2020 (COVID-19 era). Multivariate logistic regression was performed to identify predictors of mortality for both periods.
Maternal and newborn care during the COVID-19 pandemic in Kenya: re-contextualizing the community midwifery model

AUTHOR(S)
Rachel Wangari Kimani; Rose Maina; Constance Shumba (et al.)

Published: November 2020   Journal: Human Resources for Health
Peripartum deaths remain significantly high in low- and middle-income countries, including Kenya. The COVID-19 pandemic has disrupted essential services, which could lead to an increase in maternal and neonatal mortality and morbidity. Furthermore, the lockdowns, curfews, and increased risk for contracting COVID-19 may affect how women access health facilities. SARS-CoV-2 is a novel coronavirus that requires a community-centred response, not just hospital-based interventions. In this prolonged health crisis, pregnant women deserve a safe and humanised birth that prioritises the physical and emotional safety of the mother and the baby. There is an urgent need for innovative strategies to prevent the deterioration of maternal and child outcomes in an already strained health system. 
COVID-19 in pregnancy: the foetal perspective: a systematic review

AUTHOR(S)
Rajani Dube; Subhranshu Sekhar Kar

Published: October 2020   Journal: BMJ Paediatrics Open
We aimed to conduct a systematic review of the available literature to determine the effects of confirmed cases of COVID-19 in pregnant women from the foetal perspective by estimation of mother to child transmission, perinatal outcome and possible teratogenicity.
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COVID-19 & Children: Rapid Research Response

UNICEF Innocenti is mobilizing a rapid research response in line with UNICEF’s global response to the COVID-19 crisis. The initiatives we’ve begun will provide the broad range of evidence needed to inform our work to scale up rapid assessment, develop urgent mitigating strategies in programming and advocacy, and preparation of interventions to respond to the medium and longer-term consequences of the COVID-19 crisis. The research projects cover a rapid review of evidence, education analysis, and social and economic policies.