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UNDER DEVELOPMENT UNICEF Innocenti's curated library of COVID-19 + Children research

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Journal article

Becoming a mother in the ‘new’ social world in Australia during the first wave of the COVID-19 pandemic

AUTHOR(S)
Linda Sweet; Zoe Bradfield; Vidanka Vasilevski (et al.)

Published: April 2021 Journal: Midwifery

Substantial public health measures occurred in Australian society during the COVID-19 pandemic to reduce the risk of community transmission. Little was known about the impact of these changes on childbearing women. To describe childbearing women's experiences of becoming a mother during the COVID-19 pandemic in Australia.

Journal article

Social determinants of health and Coronavirus disease 2019 in pregnancy

AUTHOR(S)
Lakha Prasannan; Burton Rochelson; Weiwei Shan (et al.)

Published: March 2021 Journal: American Journal of Obstetrics & Gynecology

The social and physical environments in which people live affect the emergence, prevalence and severity of both infectious and non-infectious diseases. There is limited data on how such social determinants of health (SDH), including neighborhood socioeconomic conditions, affect the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and severity of coronavirus disease 2019 (COVID-19) during pregnancy. This paper's objective was to determine how SDH are associated with SARS-CoV-2 infection and the severity of COVID-19 illness in hospitalized pregnant patients in New York during the global COVID-19 pandemic.

Journal article

Pregnant women perspectives on SARS-COV-2 vaccine

AUTHOR(S)
Luigi Carbone; Ilenia Mappa; Angelo Sirico (et al.)

Published: March 2021 Journal: American Journal of Obstetrics & Gynecology

Since COVID-19 vaccines have been distributed, a debate has raised on whether pregnant women should get the vaccine. No available data exist so far regarding safety, efficacy and toxicology of these vaccines when administered during pregnancy. Most of the Obstetrics and Gynecology societies suggested that pregnant could agree to be vaccinated, after a thorough counseling of risks and benefits with their gynecologists, thus leading to an autonomous decision. The aim of this study was to evaluate the attitude to COVID-19 vaccination in pregnant and breastfeeding women in Italy.

Evidence Synthesis and other Reviews

A comprehensive analysis of maternal and newborn disease and related control for COVID-19

AUTHOR(S)
Nevio Cimolai

Published: March 2021 Journal: SN Comprehensive Clinical Medicine

The maternal-fetal/newborn unit is established at risk for COVID-19 infection. This narrative review summarizes the contemporary and cumulative publications which detail maternal infection, antenatal and newborn infections, and maternal/fetal/newborn management and prevention. There is a wide spectrum of maternal disease, but the potential for severe disease albeit in a minority is confirmed. COVID-19 carries risk for preterm delivery. Pregnant females can suffer multisystem disease, and co-morbidities play a significant role in risk. Congenital infection has been supported by several anecdotal reports, but strong confirmatory data are few. No typical congenital dysmorphisms are evident. Nevertheless, placental vascular compromise must be considered a risk for the fetus during advanced maternal infections. Clinical manifestations of newborn infection have been mild to moderate and relatively uncommon.

Journal article

Management of comprehensive care of multiple-birth infants from fetal to infancy period: challenges, training, strategies

AUTHOR(S)
Tahereh Changiz; Mahboobeh Namnabati

Published: March 2021 Journal: BMC Pediatrics

Prematurity escalates the crisis of the infants a susceptible group of the society. Multiple delivery further intensifies the susceptibility of both family and health system. A comprehensive care is, thus, necessary to ensure the optimal growth and development of such multiple-births. Accompanied by trainings, challenges, and strategies, the present study was conducted based on a two-year report of comprehensive care management experience on two sets of multiple infants.

Journal article

Pregnancy-related anxiety and its associated factors during COVID-19 pandemic in Iranian pregnant women: a web-based cross-sectional study

AUTHOR(S)
Zeinab Hamzehgardeshi; Shabnam Omidvar; Arman Asadi Amoli (et al.)

Published: March 2021 Journal: BMC Pregnancy and Childbirth

Pregnancy is a risk factor for coronavirus disease 2019 (COVID-19). Pregnant women suffer from varying levels of pregnancy-related anxiety (PRA) which can negatively affect pregnancy outcomes. The aim of this study was to assess PRA and its associated factors during the COVID-19 pandemic. This web-based cross-sectional study was conducted in 2020 on 318 pregnant women purposively recruited from primary healthcare centers in Sari and Amol, Iran.

Evidence Synthesis and other Reviews

Current trends and geographical differences in therapeutic profile and outcomes of COVID-19 among pregnant women - a systematic review and meta-analysis

AUTHOR(S)
Pallavi Dubey; Bhaskar Thakur; Sireesha Reddy (et al.)

Published: March 2021 Journal: BMC Pregnancy and Childbirth

Coronavirus disease (COVID-19) has been associated with adverse pregnancy outcomes. Due to the lack of effective treatments for COVID-19, it becomes imperative to assess the geographical differences and trends in the current clinical care and outcomes of COVID-19 in pregnant women. A PubMed search was performed to screen articles reporting therapeutics and outcomes of confirmed COVID-19 in pregnant women prior to August 27, 2020. Searches, quality assessments of eligible studies, extracted and reported data were performed according to PRISMA guidelines. Meta-analyses and cumulative meta-analyses of proportions were performed for estimating each outcome and their pattern over time respectively.

Journal article

Adverse perinatal outcomes predicted by prenatal maternal stress among U.S. women at the COVID-19 pandemic onset

AUTHOR(S)
Heidi Preis; Brittain Mahaffey; Susmita Pati (et al.)

Published: March 2021 Journal: Annals of Behavioral Medicine

High stress prenatally contributes to poor maternal and infant well-being. The coronavirus disease 2019 (COVID-19) pandemic has created substantial stress for pregnant women. This study aims to understand whether stress experienced by women pregnant at the beginning of the pandemic was associated with a greater prevalence of adverse perinatal outcomes

Journal article

The impact of the COVID-19 pandemic on pregnancy planning behaviors

AUTHOR(S)
Angela C. Flynn; Kimberley Kavanagh; Andrea D. Smith (et al.)

Published: March 2021 Journal: Womens Health Reports

Our understanding of how the coronavirus disease 2019 (COVID-19) pandemic has impacted decision-making for women planning to conceive is unclear. This paper aimed to investigate how the COVID-19 pandemic has influenced pregnancy planning behaviors. An online questionnaire of closed- and open-ended questions was utilized to capture pregnancy planning behaviors and reported behavioral changes during the COVID-19 pandemic in women planning pregnancy between January and July 2020. Closed-ended questions were analyzed quantitatively, and thematic framework analysis was utilized for open-ended responses.

Journal article

Future vaccinations in pregnancy

AUTHOR(S)
D. Vress

Published: March 2021 Journal: Best Practice & Research Clinical Obstetrics & Gynaecology

Vaccination in pregnancy provides an important opportunity to target illnesses that are known to impact particularly on pregnant women, fetal development and cause newborn illness. The ability to create antibodies via safe vaccination that cross the placenta can provide protection against maternal, congenital and newborn infection. There are currently multiple vaccines being developed which have direct benefits for pregnant women and their newborns. Group B Streptococcus, Respiratory Syncytial Virus, Cytomegalovirus, Zika, Ebola, Malaria and coronavirus SARS-CoV-2 are all being researched with the view to developing a safe vaccine available for pregnant women. There is also an increased movement towards including pregnant women in vaccine development and trials, challenging the historical, ethical and medicolegal arguments against their involvement in such research.

Journal article

Outcomes of newborns to mothers with COVID-19

AUTHOR(S)
K. Ghema; M. Lehlimi; H. Toumi (et al.)

Published: March 2021 Journal: Infectious Diseases Now

Coronavirus disease 2019 (COVID-19) has spread rapidly across the world. Given the sharply increased infection rate, the number of pregnant women and children with COVID-19 is correspondingly on the rise. SARS-CoV-2 infection is transmitted through droplets; though hypothesized, other transmission routes have not been confirmed. As of now, it remains unclear whether and how SARS-CoV-2 can possibly be transmitted from the mother to the fetus. This study examines the medical records of 30 neonates born to women with COVID-19, the objective being to provide documented information on maternal-child transmission and infant outcomes.

Journal article

Maintaining maternal–newborn safety during the COVID-19 pandemic

AUTHOR(S)
Nancy A. Patric; Teresa S. Johnson

Published: March 2021 Journal: Nursing for Women's Health

COVID-19, the disease caused by the SARS-CoV-2 virus, was declared a global pandemic by the World Health Organization on March 11, 2020. In addition to older individuals and those with underlying chronic health conditions, maternal and newborn populations were also identified as being at greater risk. It became critical for hospitals and clinicians to maintain the safety of individuals in the facility and minimize the transmission of COVID-19 while continuing to strive for optimized outcomes by providing family-centered care. Rapid change during the pandemic made it appropriate to use the plan–do–study–act (PDSA) cycle to continually evaluate proposed and standard practices. Our team established an obstetric COVID-19 unit for women and newborns, developed guidelines for visitation and for the use of personal protective equipment, initiated universal COVID-19 testing, and provided health education to emphasize shared decision making.

Journal article

Midwives’ experiences of providing maternity care during the COVID-19 pandemic in Australia

AUTHOR(S)
Zoe Bradfield; Yvonne Hauck; Caroline S. E. Homer (et al.)

Published: March 2021 Journal: Women and Birth

The COVID-19 pandemic has required rapid and radical changes to the way maternity care is provided in many nations across the world. Midwives provide care to childbearing women across the continuum and are key members of the maternity workforce in Australia. This paper aims to explore and describe midwives’ experiences of providing maternity care during the COVID-19 pandemic in Australia.

Evidence Synthesis and other Reviews

Impact of SARS-CoV-2 on the clinical outcomes and placental pathology of pregnant women and their infants: a systematic review

AUTHOR(S)
Irina Oltean; Jason Tran; Sarah Lawrence (et al.)

Published: March 2021 Journal: Heliyon

Pregnant women are susceptible to viral infections due to physiological changes such as cell-mediated immunity. No severe adverse pregnancy or neonatal outcomes have been consistently reported in 2019 novel coronavirus disease (COVID-19) positive pregnancy cases. There are controversies around the role of COVID-19 in pregnancy. A systematic review was conducted to examine clinical maternal and neonatal clinical outcomes. Studies were included if they reported SARS-CoV-2 infection among pregnant women and/or COVID-19 positive neonates as validated by positive antibody testing or viral testing using polymerase chain reaction. Case series, case reports, case-control studies, and comparative studies were included. Eight hundred and thirty-seven records were identified, resulting in 525 records for level I screening. Forty-one were included after full-text review.

Evidence Synthesis and other Reviews

Influence of SARS-COV-2 during pregnancy: a placental view

AUTHOR(S)
Marcos Aurélio Santos da Costa; Diana Babini Lapa de Albuquerque Britto; Jennyfer Martins de Carvalho (et al.)

Published: March 2021 Journal: Biology of Reproduction

Since the beginning of the current coronavirus outbreak (COVID-19), there has been great concern over a disease that has spread rapidly in several countries worldwide, with the result of several deaths, including deaths of pregnant women. Therefore, the aim of this study was to conduct a literature review on placental changes in infected pregnant women and/or asymptomatic carriers of COVID-19 during pregnancy, aiming at the possible vertical transmission. A systematic collection was carried out on the effects of that COVID-19 can cause directly and/or indirectly to pregnancy and the placenta in the following databases: Pubmed, Science Direct, Scielo, Lilacs, and Web of Science.

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