Children and COVID-19 Research Library

Long COVID-19 syndrome is a complex of symptoms that occurs after the acute SARS-CoV-2 infection, in the absence of other possible diagnoses. Studies on Long COVID-19 in pediatric population are scanty and heterogeneous in design, inclusion criteria, outcomes, and follow-up time. The objective of the present study is to assess the prevalence of Long COVID-19 syndrome in a cohort of Italian pediatric primary care patients, observed for a period of time of 8 to 36 weeks from healing. Prevalence was also assessed in a cohort of pediatric patients hospitalized during acute infection. Data concerning 629 primary care patients with previous acute SARS-CoV-2 infection were collected by a questionnaire filled in by Primary Care Pediatrician (PCP). The questionnaire was administrated to patients by 18 PCPs based in 8 different Italian regions from June to August 2021. Data concerning 60 hospitalized patients were also collected by consultation of clinical documents.

The proportion of children affected with COVID-19 accounted for approximately 1 to 2 % of all infected cases and the disease often follows a mild to moderate disease. Increased coagulation and events that are thrombotic were repeatedly recorded in adult patients with COVID-19. Nevertheless, till now, there is no consensus about thrombotic events in children in published articles.  This studyaimes to make evaluation of d-dimer level in children with COVID-19 and the rate of thrombotic complications. The present research that is of cross sectional type was carried out in Children and Maternity Teaching Hospital in Al-Diwaniyah Province, Iraq. The study included 168 children with COVDI-19 proved by positive RT-PCR results following nasopharyngeal swabs. The age ranged from one month up to 15 years and the study included 77 girls and 91 boys.

Post-covid syndrome (PCS) is a symptom complex that occurs during and after COVID-19 lasting more than 12 weeks, which is not a possible disease. The clinical manifestations of PCS are many-sided, under their mask or manifestations or exacerbations of chronic organic activity, the trigger of which was the virus, are hidden. PCS is a diagnosis of exclusion. The main manifestations of PCS: autonomic dysregulation, cognitive and psycho-emotional disorders, disorders of the respiratory system, cardiovascular, digestive systems. Direct pathogenic factors, the main neurological manifestations are PCS of preservation of brain hypoperfusion, hypoxia and hypoxemia, resulting in energy deficiency of neuronal structures, violation of the probable, as well as virus-induced structural detection of neurons in the cortex and subcortical structures of the brain. The severity and duration of exposure appear to be increasingly dependent on the body's response to SARS-CoV-2. PCS has a different severity of severity in recovered patients and does not always depend on the severity of the acute period. Timely examination with differential diagnosis allows not only to make a diagnosis, but also to recommend therapy with a personalized approach to the correction of PCS.

Concerns that athletes may be at a higher risk for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission has led to reduced participation in sports during the COVID-19 pandemic. This study aimed to assess COVID-19 incidence and transmission during the spring 2021 high school and college water polo seasons across the United States. This prospective observational study enrolled 1825 water polo athletes from 54 high schools and 36 colleges. Surveys were sent to coaches throughout the season, and survey data were collected and analyzed.

Obesity is a well-recognized risk factor for critical illness and death among adult patients with SARS-CoV-2 infection. This study aimed to characterize the clinical outcomes and risk factors of death related to obesity in a cohort of hospitalized paediatric patients with COVID-19. It performed an analysis of all paediatric patients with obesity and COVID-19 registered in SIVEP-Gripe, a Brazilian nationwide surveillance database, between February 2020 and May 2021. The primary outcome was time to death, which was evaluated by using cumulative incidence function.

Since viral infections are one of the most important factors affecting asthma control, various precautions and recommendations for asthma patients came to the fore at the beginning of the COVID-19 pandemic. This study, aimed to evaluate the effects of the COVID-19 pandemic on asthma control and treatment steps of children with asthma.

Whether long coronavirus disease pertains to children as well is not yet clear. The authors performed a survey in children suffering from persistent symptoms since initial infection. A total of 510 children infected between January 2020 and January 2021 were included.

There is a scarcity of population-level data of pediatric COVID-19 infection from Southeast Asia. This study aims to describe and compare epidemiological, clinical, laboratory and outcome data among pediatric COVID-19 cases versus controls in two neighboring countries, Singapore and Malaysia. It used a test-negative case–control study design recruiting all suspected COVID-19 cases (defined by either clinical or epidemiological criteria) from January 2020to March 2021 admitted to two main pediatric centers in Singapore and Malaysia. Data were collected using a standardized registry (Pediatric Acute and Critical Care COVID-19 Registry of Asia).

The effects of COVID-19 on children are still poorly understood. Considering the progressive increase in pediatric cases, we sought to gather evidence of the disease in children, to better understand its evolution, possible complications, and favor clinical practice. This is a review, whose search was carried out in the National Library of Medicine, Latin American & Caribbean Health Sciences Literature (LILACS), Medical Literature Analysis and Retrieval System Online, Virtual Health Library (BVS), PAHO and Cochrane Library. Eight articles were included, and the most common symptoms described were: cold-like symptoms, dry cough, respiratory difficulty, mild throat infection, loss of muscle strength, tonic and reflex changes in the lower limbs. However, there is still no clarity about the disease in children, requiring further research.

COVID-19 literacy is very important in dealing with the current pandemic, especially for students who will or are carrying out offline learning. So, it is necessary to develop an instrument that can measure the literacy ability of COVID-19. This study aims to develop an instrument that can assess the COVID-19 literacy level of high school students. The research method used is research and development with Borg & Gall model, which consists of eight stages namely (1) research and initial information collection, (2) designing, (3) developing initial products, (4) expert validation, (5) initial product revision based on input from expert validators; (6) Field trials, (7) revision, (8) implementation and dissemination. The results of the development obtained 28 items consisting of eight questionnaires and 20 multiple choice questions. The questionnaire aims to obtain descriptive data about students' attitudes towards the COVID-19 pandemic, while multiple choice questions are used to measure students' knowledge.

This study aims to evaluate the impact of COVID-19 mitigation measures on the total number of consultations for respiratory and gastrointestinal infections among children under 16 years in Thai Binh Pediatric Hospital, Vietnam during the year 2020. A retrospective study was carried out to review consecutive consultations occurring in children admitted from January 01, 2016 to December 31, 2020. All medical records were collected from the central numeric database of the hospital. Diagnoses were documented according to the International Classification of Diseases 10 criteria.