search advanced search
UNICEF Innocenti
Office of Research-Innocenti
search menu

Children and COVID-19 Research Library

UNICEF Innocenti's curated library of COVID-19 + Children research

RESULTS:   120     SORT BY:

ADVANCED SEARCH:

Select one or more filter options and click search below.

PUBLICATION DATE:
UNICEF Innocenti Publication
UNICEF Publication
Open Access
JOURNAL ACCESS FOR UNICEF STAFF CONTACT US
31 - 45 of 120
COVID-19 and pregnancy

AUTHOR(S)
Sonja A. Rasmussen; Denise J. Jamieson

Published: January 2022   Journal: Infectious Disease Clinics of North America
Since the emergence of SARS-CoV-2 in late 2019, the virus and the response to it have had catastrophic effects on the world’s health, societies, and economies. Early on, data on the effects of SARS-CoV-2 on the pregnant person and fetus were limited. Data on the effects during pregnancy of previous coronaviruses (severe acute respiratory syndrome [SARS] and Middle East respiratory syndrome [MERS]) are sparse, but those data along with information on other respiratory infections such as influenza raised concerns about the potential effects of COVID-19 during pregnancy.This study reviews available information on the effects of SARS-CoV-2 infection during pregnancy and on the effectiveness and safety of the SARS-CoV-2 vaccines in protecting pregnant persons and their newborns from COVID-19.
Distress, anxiety, and its correlates among caregivers of children with kidney diseases during COVID-19 pandemic lockdown

AUTHOR(S)
Rajni Sharma; Bikramjit Singh Jafra; Karalanglin Tiewsoh (et al.)

Published: January 2022   Journal: Archives de Pédiatrie

The COVID-19 pandemic has generated a significant amount of psychological burden in the form of stress, anxiety, uncertainty, depression, anger, and helplessness. The caregivers of children with chronic diseases in particular are at a higher risk of mental stress and burden. This online survey among caregivers of children with kidney diseases was conducted to assess the psychosocial impact of COVID-19. The psychosocial impact of COVID-19 pandemic on their mental health was assessed through standardized psychological scales (Peritraumatic Distress Inventory, Insomnia Severity Scale [ISI], Depression Anxiety and Stress Scale [DASS], and Positive and Negative Aspect Scale) and a semi-structured interview was conducted telephonically.

Hispanic race is a risk factor for COVID-19 during pregnancy: data from an urban New York City hospital

AUTHOR(S)
Deena Elkafrawi; Giovanni Sisti; Felipe Mercado (et al.)

Published: January 2022   Journal: Journal of Obstetrics and Gynaecology

There are limited studies on predisposing factors for COVID-19 positivity in asymptomatic pregnant women. The literature published to date on asymptomatic COVID-19 pregnant carriers does not focus on pregnancy or pre-pregnancy comorbidities. This study wanted to identify risk factors for COVID-19 in asymptomatic pregnant women. It performed a retrospective chart review of 263 asymptomatic pregnant women admitted to labour and delivery at New York City Health + Hospitals/Lincoln. It analysed the association between race, body mass index (BMI), smoking, indication for admission, gravidity, parity, pre-pregnancy comorbidity, pregnancy comorbidity via uni- and multivariate statistical tests. Only Hispanic race was significant in the univariate analysis (p = .049). At the post-hoc analysis, Hispanics had a higher proportion of COVID-19 cases compared to non-Hispanic Blacks (p = .019). No variables were significantly associated with COVID-19 positivity in the multivariate analysis.

Attitudes towards influenza and pneumococcal vaccines in parents of asthmatic children during the COVID-19 pandemic

AUTHOR(S)
Murat Özer; Nevzat Başkaya; İlknur Bostancı

Published: January 2022   Journal: Pediatric Pulmonology

This study aimed to determine the differences in attitudes and views towards influenza and pneumococcal vaccines in parents of children with asthma during the COVID-19 pandemic. Asthmatic children in the 6–18 age group who were admitted to the pediatric allergy clinic of our hospital between October 1, 2020 and February 31, 2021 were included in the study. The parents were given a questionnaire asking about their demographics and medical history. Their attitudes and thoughts towards these two vaccines, both before and during the pandemic, and their COVID-19 stories were questioned.

The impact of the COVID-19 pandemic on respiratory morbidity during infancy: a birth-cohort study

AUTHOR(S)
Nataly Rosenfeld; Avigdor Mandelberg; Ilan Dalal (et al.)

Published: January 2022   Journal: Pediatric Pulmonology

To evaluate the incidence of wheezing and overall respiratory morbidity in healthy infants born during the first peak of the coronavirus disease-2019 (COVID-19) pandemic, compared with infants born during the preceding year. This was a single-center retrospective birth cohort study to compare a cohort of children born between February and March 2020 (COVID-19 group) to a control group of children born between February and March 2019 (pre-COVID-19 group). At 1 year of age, this study collected respiratory data using parental and telephone questionnaires. Primary outcome: wheezing incidence and/or bronchodilator use. Secondary outcomes: recurrent wheezing, emergency-room visits, hospital admissions, pneumonia diagnosis, and admissions due to lower-respiratory-tract-infections (LRTI). It included the following covariate risk factors in the logistic regression models; atopy, daycare attendance, breastmilk feeding, parental smoking, C-section, siblings, and gestational age.

Long COVID symptoms and duration in SARS-CoV-2 positive children — a nationwide cohort study

AUTHOR(S)
Luise Borch; Mette Holm; Maria Knudsen (et al.)

Published: January 2022   Journal: European Journal of Pediatrics
Most children have a mild course of acute COVID-19. Only few mainly non-controlled studies with small sample size have evaluated long-term recovery from SARS-CoV-2 infection in children. The aim of this study was to evaluate symptoms and duration of ‘long COVID’ in children. A nationwide cohort study of 37,522 children aged 0–17 years with RT-PCR verified SARS-CoV-2 infection (response rate 44.9%) and a control group of 78,037 children (response rate 21.3%). An electronic questionnaire was sent to all children from March 24th until May 9th, 2021.
Severe COVID-19 and MIS-C in children & adolescents

AUTHOR(S)
Allison M. Blatz; Adrienne G. Randolph

Published: January 2022   Journal: Critical Care Clinics
Severe complications related to COVID-19 occur infrequently in children and adolescents. The two major types of life-threatening complications are acute respiratory failure from acute COVID-19 and Multisystem Inflammatory Syndrome in Children (MIS-C). MIS-C is a post-infectious complication occurring approximately 3-6 weeks after an asymptomatic or mild SARS-CoV-2 infection. For both types of complications, supportive ICU care is provided. For MIS-C critical illness, immunomodulation is prescribed to reverse hyperinflammation and its cardiac and other sequelae
Comparison of the first and second waves of the COVID-19 pandemic in children and adolescents in a middle-income country: Clinical impact associated with SARS-CoV-2 gamma lineage

AUTHOR(S)
Eduardo A. Oliveira; Ana Cristina Simões e Silva; Maria Christina L. Oliveira (et al.)

Published: January 2022   Journal: The Journal of Pediatrics

To evaluate the severity and clinical outcomes of the SARS-CoV-2 gamma variant in children and adolescents hospitalized with COVID-19 in Brazil. In this observational retrospective cohort study, we performed an analysis of all 21,591 hospitalized patients aged < 20 years with confirmed SARS-CoV-2 infection registered in a national database in Brazil. The cohort was divided into two groups according to the predominance of SARS-CoV-2 lineages (WAVE1, n = 11,574 and WAVE2, n = 10,017). The characteristics of interest were age, sex, geographic region, ethnicity, clinical presentation, and comorbidities. The primary outcome was time to death, which was evaluated by competing-risks analysis, using cumulative incidence function. A predictive Fine-Gray competitive risks model was developed based on WAVE1 cohort with temporal validation in WAVE2 cohort.

Neonatal outcome among pregnant women with COVID-19: a systematic review and meta-analysis

AUTHOR(S)
Azam Amirian; Reza Pakzad; Vajiheh Hasanpour (et al.)

Published: January 2022   Journal: The Journal of Maternal-Fetal & Neonatal Medicine

COVID-19 has raised many concerns about the possible side effects of pregnancy. There is currently no conclusive evidence of the vertical transmission of COVID-19. Accordingly, this paper is a Systematic Review and Meta-Analysis investigated neonatal outcomes among pregnant women with COVID-19. PubMed, Web of Science (WoS), EMBASE, ProQuest, Scopus, and Google Scholar were searched up to November 2020. The Cochran's Q-test and I2 statistic were applied to assess heterogeneity, a random-effects model was used to estimate the pooled estimate of the mean, and a meta-regression method was utilized to investigate the factors affecting heterogeneity between studies.

Masking for school-age children with epilepsy: we do have consensus!: masking for children with epilepsy

AUTHOR(S)
Anthony I. Fine; Lily C. Wong-Kisiel; Katherine C. Nickels (et al.)

Published: January 2022   Journal: Journal of child neurology

This study was designed to assess current recommendations from child neurologists and epileptologists on masking for school-age children with epilepsy. A 7-item survey was created and sent out to members of the Child Neurology Society and Pediatric Epilepsy Research Consortium in August of 2021 to assess current practice and provider recommendations on masking.

SARS-CoV-2 infection in children in Moscow in 2020: clinical features and impact on circulation of other respiratory viruses

AUTHOR(S)
Alexander S. Yakovlev; Ilmira K. Belyaletdinova; Lyudmila N. Mazankova (et al.)

Published: January 2022   Journal: International journal of infectious diseases

The aim of this study was to estimate the impact of the COVID-19 pandemic on the circulation of non-SARS-CoV-2 respiratory viruses and clinical characteristics of COVID-19 in hospitalized children. 226 and 864 children admitted to Children's City Clinical Hospital with acute respiratory infection in September-November of 2018 and 2020 in Moscow were tested for respiratory viruses using multiplex PCR and Mycoplasma pneumoniae/Chlamydia pneumoniae using ELISA.

Stress, dependence, and COVID-19–related changes in past 30-day marijuana, electronic cigarette, and cigarette use among youth and young adults

AUTHOR(S)
Stephanie L. Clendennen; Kathleen R. Case; Aslesha Sumbe (et al.)

Published: December 2021   Journal: Tobacco Use Insights

Studies show smoking and vaping behaviors increase risk of contracting and worse symptoms of COVID-19. This study examines whether past 30-day youth and young adult users of marijuana, e-cigarettes, and cigarettes self-reported changes in their use of these substances due to the COVID-19 pandemic; and cross-sectional associations between perceived stress, nicotine or marijuana dependence, and COVID-19–related changes in use. Participants were 709 past 30-day self-reported substance users from the Texas Adolescent Tobacco and Marketing Surveillance study (TATAMS; mean age = 19; 58% female; 38% Hispanic, 35% white). Multiple logistic regression models assessed cross-sectional associations between perceived stress and dependence and increased, decreased, or sustained past 30-day use of marijuana, e-cigarettes, and cigarettes due to COVID-19 (e.g., “Has your marijuana use changed due to the COVID-19 outbreak?”). Covariates included age, race/ethnicity, socio-economic status (SES), dependence (exposure: stress), and stress (exposure: dependence).

Transmission of SARS-CoV-2 by children and young people in households and schools: a meta-analysis of population-based and contact-tracing studies

AUTHOR(S)
Russell Viner; Claire Waddington; Oliver Mytton (et al.)

Published: December 2021   Journal: Journal of Infection
The role of children and young people (CYP) in transmission of SARS-CoV-2 in household and educational settings remains unclear. This study undertook a systematic review and meta-analysis of contact-tracing and population-based studies at low risk of bias. It searched 4 electronic databases on 28 July 2021 for contact-tracing studies and population-based studies informative about transmission of SARS-CoV-2 from 0-19 year olds in household or educational settings. It excluded studies at high risk of bias, including from under-ascertainment of asymptomatic infections. It undertook multilevel random effects meta-analyses of secondary attack rates (SAR: contact-tracing studies) and school infection prevalence, and used meta-regression to examine the impact of community SARS-CoV-2 incidence on school infection prevalence.
Decreased risk of COVID-19 pneumonia in children and adolescents during the Delta variant emergence

AUTHOR(S)
Efrén Murillo-Zamora; Xóchitl Trujillo; Miguel Huerta (et al.)

Published: December 2021   Journal: Public Health

This study aims to evaluate factors associated with the risk of COVID-19 pneumonia in children (<10 years old) and adolescents (10 - 19 years old) before (March 2020 - April 2021) and during (May - July 2021) the Delta (B.1.617.2) variant emergence. A retrospective and nationwide cohort study was conducted in Mexico. Data from 26,961 laboratory-confirmed cases of COVID-19 were analyzed. Risk ratios (RR) and 95% confidence intervals (IC) were used to evaluate the association of the evaluated exposures with the risk of COVID-19 pneumonia.

Characteristics, contacts, and relative risk of SARS-CoV-2 infection among children during school closures

AUTHOR(S)
Jun Yi Sim; Ping-Sheng Wu; Ching-Feng Cheng (et al.)

Published: December 2021   Journal: Journal of Microbiology, Immunology and Infection

Characteristics of children with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in Taiwanese households is nascent. This study sought to characterize SARS-CoV-2 infection, and estimate the relative risk of infection among children within households during school closures in Taipei and New Taipei City. It reviewed consecutive children below 18 years presenting to our emergency department from May 18, 2021 to July 12, 2021 who underwent real-time reverse-transcription polymerase chain reaction (rRT-PCR) for SARS-CoV-2 from respiratory swabs. Demographics, symptoms, and contacts were captured from medical records. Household contact was defined as an individual with confirmed COVID-19 living in the same residence as the child.

31 - 45 of 120

UNICEF Innocenti's Children and COVID-19 Library is a database collecting research from around the world on COVID-19 and its impacts on children and adolescents.

LEARN MORE ABOUT THE DATABASE

Read the latest quarterly digest on children and disabilities.

The second digest discussed children and violence during the pandemic.

The first digest covers children and youth mental health under COVID-19.

Subscribe to updates on new research about COVID-19 & children

SIGN UP TO OUR NEWSLETTER

Share:

facebook twitter linkedin google+ reddit print email
Campaign Campaign

COVID-19 & Children: Rapid Research Response

UNICEF Innocenti is mobilizing a rapid research response in line with UNICEF’s global response to the COVID-19 crisis. The initiatives we’ve begun will provide the broad range of evidence needed to inform our work to scale up rapid assessment, develop urgent mitigating strategies in programming and advocacy, and preparation of interventions to respond to the medium and longer-term consequences of the COVID-19 crisis. The research projects cover a rapid review of evidence, education analysis, and social and economic policies.