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Children and COVID-19 Research Library

UNICEF Innocenti's curated library of COVID-19 + Children research

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Parental COVID-19 vaccination hesitancy among parents of children aged 5-18 years in Thailand: a cross-sectional survey study

Pantira Parinyarux; Kanokkarn Sunkonkit; Kitiyot Yotsombut

Published: October 2022   Journal: Journal of Pharmaceutical Policy and Practice

To promote an acceptance rate of COVID-19 immunization among Thai children, concerns about parental vaccination hesitancy should be urgently studied. This study aimed to examine the parental COVID-19 vaccination hesitancy (PVh) level and influencing factors among Thai parents of children 5–18 years of age. This cross-sectional survey was conducted in Thailand during May and June of 2022. The Google forms for data collection were distributed to parents (a father, a mother, or one who nurtures and raises a child) via various online social media. Data regarding PVh level, relevant attitudes, experiences of COVID-19 and COVID-19 vaccination (EC&V), and family contexts (FC) were collected and analyzed using descriptive statistics. Mann–Whitney U test was used to compare the differences among groups of parents based on EC&V and FC. The factors influencing PVh were assessed by multiple regression analysis.

Relationship attitude with student parent acceptance against COVID-19 vaccine in elementary school children age (6-11 years) in Makassar city

Firman ; Ansariadi ; Andi Zulkifli (et al.)

Published: October 2022   Journal: InternationalJournal of Health Sciences

This study examines the relationship between attitudes and parental acceptance of the COVID-19 vaccine in elementary school children aged (6-11 years) in Makassar City. The type of research used is analytic observational with a cross sectional study design. The population in this study were all parents of students with school-age children (6-11 years) in Makassar City who were categorized as eligible for vaccination, which was around 264,000 people. While the number of samples as many as 1,073 parents of students. The sampling technique used is snowball sampling. Data were analyzed using SPSS with Chi-square test. Data analysis performed was univariate and bivariate. The results showed that the attitude variable had a significant relationship (p<0.05).

Cite this research | Open access | Issue: Special Issue VII | No. of pages: 7 | Language: English | Topics: Health | Tags: child health, COVID-19, immunization, immunization programmes, infectious disease, pandemic, vaccination, vaccination policies | Countries: Indonesia
Vaccine effectiveness, school reopening, and risk of Omicron infection among adolescents aged 12-17 years

Malcolm Risk; Heidi Miao; Gary Freed (et al.)

Published: October 2022   Journal: Journal of Adolescent Health
The BNT162b2 (Pfizer-BioNTech) is approved for adolescents aged 12–17 years. This study estimated BNT162b2 vaccine effectiveness (VE) and a booster dose effectiveness in adolescents aged 12–17 years and the impact of opening schools and the Omicron variant on risk of SARS-CoV-2 infection in adolescents. It used logistic regression with a test-negative design controlling for gender and race to estimate BNT162b2 VE and the effectiveness of a booster dose in adolescents aged 12–17 years. To evaluate the effect of school opening on Omicron transmission, it used Cox proportional hazards regression to compare adolescents to a reference group of adults aged 22–33 or aged 65+ years, investigating whether risk for adolescents increased relative to the reference group after school opened.
Predicting vaccine hesitancy among parents towards COVID-19 vaccination for their children in Singapore

Jia Ming Low; Chloe Wen Ting Soo; T. A. Phuong (et al.)

Published: October 2022   Journal: Frontiers in Pediatrics

There was a considerably slower uptake among children despite the high COVID-19 vaccination uptake amongst adults and adolescents in Singapore. This was concerning as unvaccinated children are at risk of severe COVID-19 infections and a source and reservoir of infections. We sought to understand the impact of social media on parental vaccine hesitancy and to determine the risk factors associated with vaccine hesitancy.  An electronic survey conducted from November 2021 to March 2022. Data on the demographic profiles of respondents and to classify them based on their vaccine hesitancy status. Data including the choice of social media used to obtain information on the COVID-19 pandemic, frequency of use were collected. Statistical significance was defined as p < 0.05.

Fear of COVID-19 and vaccine hesitancy among pregnant women in Poland: a cross-sectional study

Kinga Janik; Kinga Nietupska; Grazyna Iwanowicz-Palus (et al.)

Published: October 2022   Journal: Vaccines
Pregnant women are particularly vulnerable to anxiety and stress, and the COVID-19 pandemic has definitely contributed to anxiety in this group. Researchers continue their work on COVID-19 vaccine formulations to reduce the spread of the SARS-CoV-2 virus and minimise the impact of the pandemic. Despite the increased prevalence and severity of anxiety among pregnant women during the COVID-19 pandemic, their attitudes towards COVID-19 vaccine vary. The aim of this study was to assess the levels of anxiety experienced by pregnant women due to COVID-19 and their attitudes to vaccination. Materials and methods: A total of 595 women voluntarily participated in the study. The respondents were divided into two groups: the study group (n = 288), which consisted of women who were pregnant at the time of the survey, and the control group (n = 307), which included women of reproductive age (18–49 years). The study used a diagnostic survey method with a web-based questionnaire consisting of the author’s survey questionnaire and the following standardised tools: the Scale to Measure the Perception of SARS-CoV-2 Vaccines Acceptance (VAC-COVID-19 SCALE), the Fear of COVID-19 Scale (FCV-19S), the Drivers of COVID-19 Vaccination Acceptance Scale (DrVac-COVID19S) and the Coronavirus Anxiety Scale (CAS).
The COVID-19 pandemic and vaccination abandonment in children: spatial heterogeneity maps

Rayssa Nogueira Rodrigues; Gabriela Lourença Martins do Nascimento; Luiz Henrique Arroyo (et al.)

Published: September 2022   Journal: Revista Latino-Americana de Enfermagem

This study aims to identify spatial clusters corresponding to abandonment of routine vaccines in children. It is an ecological study, according to data from the 853 municipalities of a Brazilian state. The records analyzed were those of the multidose pentavalent, pneumococcal 10-valent, inactivated poliomyelitis and oral human rotavirus vaccines of 781,489 children aged less than one year old. The spatial scan statistics was used to identify spatial clusters and assess the relative risk based on the vaccination abandonment indicator.

Outcomes at least 90 days since onset of myocarditis after mRNA COVID-19 vaccination in adolescents and young adults in the USA: a follow-up surveillance study

Ian Kracalik; Matthew E. Oster; Karen R. Broder (et al.)

Published: September 2022   Journal: The Lancet Child & Adolescent Health
Data on medium-term outcomes in indivduals with myocarditis after mRNA COVID-19 vaccination are scarce. This study aimed to assess clinical outcomes and quality of life at least 90 days since onset of myocarditis after mRNA COVID-19 vaccination in adolescents and young adults. This follow-up surveillance study conducted surveys in US individuals aged 12–29 years with myocarditis after mRNA COVID-19 vaccination, for whom a report had been filed to the Vaccine Adverse Event Reporting System between Jan 12 and Nov 5, 2021. A two-component survey was administered, one component to patients (or parents or guardians) and one component to health-care providers, to assess patient outcomes at least 90 days since myocarditis onset. Data collected were recovery status, cardiac testing, and functional status, and EuroQol health-related quality-of-life measures (dichotomised as no problems or any problems), and a weighted quality-of-life measure, ranging from 0 to 1 (full health). The EuroQol results were compared with published results in US populations (aged 18–24 years) from before and early on in the COVID-19 pandemic.
Risk of COVID-19 hospitalizations among school-aged children in Scotland: a national incident cohort study

Ting Shi; Jiafeng Pan; Emily Moore (et al.)

Published: September 2022   Journal: Journal of Global Health

There is considerable policy, clinical and public interest about whether children should be vaccinated against SARS-CoV-2 and, if so, which children should be prioritised (particularly if vaccine resources are limited). To inform such deliberations, we sought to identify children and young people at highest risk of hospitalization from COVID-19. This study used the Early Pandemic Evaluation and Enhanced Surveillance of COVID-19 (EAVE II) platform to undertake a national incident cohort analysis to investigate the risk of hospitalization among 5-17 years old living in Scotland in risk groups defined by the living risk prediction algorithm (QCOVID). A Cox proportional hazard model was used to derive hazard ratios (HR) and 95% confidence intervals (CIs) for the association between risk groups and COVID-19 hospital admission. Adjustments were made for age, sex, socioeconomic status, co-morbidity, and prior hospitalization.

Intrinsic kidney pathology in children and adolescents following COVID-19 vaccination: a systematic review

Henry H. L. Wu; Mohan Shenoy; Philip A. Kalra (et al.)

Published: September 2022   Journal: Children
Global COVID-19 vaccination programs for children and adolescents have been developed with international clinical trial data confirming COVID-19 mRNA vaccine safety and efficacy for the pediatric population. The impact of COVID-19 vaccination in the kidneys is thought to be explained by a complex immune-mediated relationship between the two, although the pathophysiological mechanisms of how COVID-19 vaccination potentially induces kidney pathology are not presently well known. Whilst intrinsic kidney pathologies following COVID-19 vaccination have been reported in adults, such cases are only being recently reported with greater frequency in children and adolescents. Conforming to the PRISMA checklist, this study conducted a systematic review of the current literature to provide an overview on the range of intrinsic kidney pathologies that have been reported following COVID-19 vaccination in children and adolescents. All English language research articles published on or before 30 June 2022 reporting new-onset or relapsed intrinsic kidney pathology in children or adolescents (≤18 years) following COVID-19 vaccination were selected for qualitative analysis.
COVID-19 vaccine acceptance among pregnant women worldwide: a systematic review and meta-analysis

Milad Azami; Marzieh Parizad Nasirkandy; Hadi Esmaeili Gouvarchin Ghaleh (et al.)

Published: September 2022   Journal: Plos One

The COVID-19 pandemic has led to the death of many people worldwide. The World Health Organization (WHO) has declared vaccine resistance as one of the greatest health threats in the world even before the COVID-19 epidemic. The aim of this study was to evaluate the acceptance of COVID-19 vaccine in pregnant women. A systematic review and meta-analysis in accordance with the PRISMA guidelines was performed. The standard search strategy to the PubMed/Medline, Web of Science (ISI), Scopus, Science Direct, Cochrane Library, EMBASE, and EBSCO databases, and the Google Scholar search engine was applied. Heterogeneity between studies was relatively high and therefore meta-analyses were performed based on random effects model with 95% CI using STATA version 16.

Comparing COVID-19 vaccination outcomes with parental values, beliefs, attitudes, and hesitancy status, 2021–2022

Tuhina Srivastava; Angela K. Shen; Safa Browne (et al.)

Published: September 2022   Journal: Vaccines
Despite the availability of safe and effective COVID-19 vaccines, vaccine acceptance has been low, particularly among parents. More information is needed on parental decision-making. A prospective cohort study was conducted from October 2021 to March 2022 among 334 parents in a large urban/suburban pediatric primary care network and linked longitudinal survey responses about attitudes and beliefs on vaccination, social norms, and access to vaccination services for COVID-19 to electronic health-record-derived vaccination outcomes for their eldest age-eligible children in June 2022. The odds of accepting two doses of COVID-19 vaccine for their child was higher in respondents who indicated the COVID-19 vaccine would be very safe (aOR [CI]: 2.69 [1.47–4.99], p = 0.001), as well as those who previously vaccinated their child against influenza (aOR [CI]: 4.07 [2.08–8.12], p < 0.001). The odds of vaccinating their child were lower for respondents who attended suburban vs. urban practices (aOR [CI]: 0.38 [0.21–0.67], p = 0.001). Parents in the cohort were active users of social media; the majority (78%) used their phone to check social media platforms at least once per day.
Cite this research | Open access | Vol.: 10 | Issue: 10 | No. of pages: 14 | Language: English | Topics: Health | Tags: child health, COVID-19, immunization, immunization programmes, pandemic, parents, vaccination, vaccination policies | Countries: United States
What do adolescents think about vaccines? Systematic review of qualitative studies

Hana Mitchell; Rebecca Lim; Prubjot K. Gill (et al.)

Published: September 2022   Journal: PLOS Global Public Health
Adolescence presents a key opportunity to build vaccine-related health literacy and promote vaccine confidence and uptake. Although adolescents are central to vaccination programs, their views around vaccines are frequently underrepresented in qualitative literature. We reviewed qualitative studies to systematically identify and summarize existing evidence on adolescents’ own understanding of vaccines and experiences with vaccine decision-making, including self-consent when applicable. CINAHL; Embase; Ovid Medline; and Psych Info database searches were last updated on May 28, 2022. Data pertaining to general study characteristics, participant demographics, and qualitative content were extracted independently by two reviewers and analyzed using textual narrative synthesis.
Can high COVID-19 vaccination rates in adults help protect unvaccinated children? Evidence from a unique mass vaccination campaign, Schwaz/Austria, March 2021

Hannes Winner; Janine Kimpel; Florian Krammer (et al.)

Published: September 2022   Journal: Eurosurveillance

In 2021, many countries still did not have vaccines against coronavirus disease (COVID-19) available for young age cohorts. In addition, some parents were and still are hesitant regarding potential risks and benefits of inoculating their children, meaning that vaccination coverage for this population remains modest. This raises the important question whether population immunity can be achieved by high vaccination rates when a sufficiently large share of vaccinated adults provide indirect protection to unvaccinated individuals in the community. If this indirect vaccination effect exists, a high coverage among older cohorts may protect younger cohorts such as children from infection. More generally, community protection may help contain the pandemic even in the presence of groups unwilling or unable to get vaccinated. This study aimed to analyse this indirect protection effect, a unique rapid mass vaccination campaign. In particular, following an outbreak of the Beta variant (Phylogenetic Assignment of Named Global Outbreak (Pango) lineage designation B.1.351) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the district of Schwaz (Austria), the government of Austria supplied 100,000 extra doses of the Comirnaty vaccine (BNT162b2 mRNA, Pfizer/BioNTech) to rapidly mass-vaccinate the entire adult population (≥ 16 years) of Schwaz.

Child vaccination coverage in India and its impact: evidence from NFHS-5 factsheet

S. Sheetal; Saransh Khanna; Shivam Kumar Shukla (et al.)

Published: September 2022

In developing countries various childhood diseases lead the morbidity, mortality and irreversible losses which can be prevented by proper vaccination. This study was conducted to analyse the changing trends of childhood vaccination in India and its impact on childhood diseases and mortality, the trends in coverage of each vaccine along with identification of geographical areas of concern. NFHS data published by Government of India was analyzed to see the trends in vaccination coverage, female literacy, childhood diseases and under-five mortality, along with online database search for relevant literature.

Attitude toward COVID-19 vaccines and its association with depressive symptoms in 386,924 Chinese primary school students during COVID-19 epidemic normalization

Qingqing Xu; Zhenxing Mao; Keliang Fan (et al.)

Published: September 2022   Journal: Journal of Psychosomatic Research

Before Chinese primary school students were generally vaccinated against the COVID-19 vaccine, this study evaluated the willingness of this population and its influencing factors before vaccination, and evaluate its association between attitudes toward the vaccine and depressive symptoms. A cross-sectional study involved 386,924 primary school students using a cluster sampling method during May 21–27, 2021. The Chinese version of the Children Depression Inventory (CDI) was used to assess depressive symptoms. Multiple logistic regression analysis models were used to estimate the relationship between attitudes toward COVID-19 vaccines and depressive symptoms.

16 - 30 of 378

UNICEF Innocenti's Children and COVID-19 Library is a database collecting research from around the world on COVID-19 and its impacts on children and adolescents.


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