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Children and COVID-19 Research Library

UNICEF Innocenti's curated library of COVID-19 + Children research

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361 - 375 of 468
Pregnancy and birth outcomes after SARS-CoV-2 vaccination in pregnancy

AUTHOR(S)
Regan N. Theiler; Myra Wick; Ramila Mehta (et al.)

Published: August 2021   Journal: American Journal of Obstetrics & Gynecology
 SARS-CoV-2 infection during pregnancy is associated with significant maternal morbidity and increased rates of preterm birth. For this reason, COVID-19 vaccine administration in pregnancy has been endorsed by multiple professional societies including ACOG and SMFM despite exclusion of pregnant women from initial clinical trials of vaccine safety and efficacy. However, to date little data exists regarding outcomes after COVID-19 vaccination of pregnant patients. A comprehensive vaccine registry was combined with a delivery database for an integrated healthcare system to create a delivery cohort including vaccinated patients. Maternal sociodemographic data were examined to identify factors associated with COVID-19 vaccination. Pregnancy and birth outcomes were analyzed, including a composite measure of maternal and neonatal pregnancy complications, the Adverse Outcome Index.
Caregivers’ sources of information about immunization as predictors of delayed childhood vaccinations in Saudi Arabia during the COVID-19 pandemic: a cross-sectional questionnaire study

AUTHOR(S)
Leena R. Baghdadi; Marwah M. Hassounah; Afnan Younis (et al.)

Published: August 2021   Journal: Risk Management and Healthcare Policy
Of 628 women, 11.8% (n = 74) were pregnant at the time of survey. Most of the pregnant women (89.2%, n = 66) had some degree of concerns about their unborn babies getting infected during delivery in the hospital. Among mothers of children under 10 years of age (n = 564), half (n = 282) reported change in their children’s behavior during the lockdown. Most mothers and pregnant women (94.9%, n = 569) had some degree of psychological distress. Mothers and pregnant women with a college degree had significantly lower psychological distress (β = -1.346; p = 0.014) than women with a high school education or less. Similarly, mothers and pregnant women with monthly family income ≥ US$ 1,333 had lower psychological distress than those with < US$ 1,333. Women with pre-existing chronic physical (β = 2.424; p < 0.001) or mental (β = 4.733; p < 0.001) conditions had higher psychological distress than those without these conditions. Having children in the house was a contributory factor for higher psychological distress. For example, mothers with one child (β = 2.602; p = 0.007) had significantly higher psychological distress compared to expectant mothers without children in the house.
Vaccine hesitancy towards childhood immunizations as a predictor of mothers’ intention to vaccinate their children against COVID-19 in Saudi Arabia

AUTHOR(S)
Haifa Aldakhil; Norah Albedah; Nouf Alturaiki (et al.)

Published: August 2021   Journal: Journal of Infection and Public Health

Despite the success of childhood immunization in reducing vaccine-preventable diseases, vaccine hesitancy is now a global health threat to this achievement. The current COVID-19 pandemic may change the picture of vaccine hesitancy toward childhood immunizations, which could influence the mothers’ intention to vaccinate their children against COVID-19. This study aims to measure the prevalence and related factors of vaccine hesitancy towards childhood immunization during the era of COVID-19 along with the prevalence of mothers’ intention to vaccinate their children the future COVID-19 and its association with childhood vaccine hesitancy.

Willingness and influential factors of parents of 3-6-year-old children to vaccinate their children with the COVID-19 vaccine in China

AUTHOR(S)
Xiao Wan; Haitao Huang; Jia Shang (et al.)

Published: August 2021   Journal: Human Vaccines & Immunotherapeutics
The impact of Coronavirus disease 2019 (COVID-19) on children aged 3–6 can be severe. Vaccination for COVID-19 is one of the most important primary preventative measures to reduce disease transmission. Parents are hesitant to vaccinate their children against COVID-19 because it was reported in the news that some adults have had adverse reactions to the vaccine. This study aims to investigate the willingness of Chinese parents of 3–6 year old children to vaccinate them with the COVID-19 vaccine and identify what factors influence their decisions. A survey was conducted using a two-stage stratified random sampling method from December 2020 to February 2021. We used univariate analysis and multivariate binary logistic analysis to explore potential factors that may determine the acceptance of the COVID-19 vaccine.
Repurposing of the childhood vaccines: could we train the immune system against the SARS-CoV-2

AUTHOR(S)
Divakar Sharma

Published: August 2021   Journal: Expert Review of Vaccines

The COVID-19 pandemic is a globalized health concern caused by a beta-coronavirus named Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Since December 2019, when this outbreak flared in Wuhan, China, COVID-19 cases have been continuously rising all over the world. Due to the emergence of SARS-CoV-2 mutants, subsequent waves are flowing in a faster manner as compared to the primary wave, which is more contagious and causing higher mortality. Recently, India has emerged as the new epicenter of the second wave by mutants of SARS-CoV-2. After almost eighteen months of this outbreak, some COVID-19 dedicated therapeutics and vaccines are available, and a few are under trial, but the situation is still uncontrolled. This perspective article covers the repurposing of childhood vaccines like Bacille Calmette–Guerin (BCG), Measles, Mumps, Rubella (MMR), and Oral Polio Vaccine (OPV), which are live attenuated vaccines and have been shown the protective effect through ‘trained immunity and ‘crossreactivity.'

Determinants of parental hesitancy to vaccinate their children against COVID-19 in China

AUTHOR(S)
Mei-Xian Zhang; Xiao-Qing Lin; Yan Chen (et al.)

Published: August 2021   Journal: Expert Review of Vaccines

Vaccine hesitancy seriously hinders herd immunity. This study explored the determinants of parental hesitancy to vaccinate children against Coronavirus Disease 2019 (COVID-19) in China. A population-based self-administered online questionnaire evaluating parental hesitancy in vaccinating their children against COVID-19 was conducted in Taizhou, China. Of the 2463 parents who received the invitation, 1788 (72.6%) responded to the survey.

Acceptance and willingness to pay for COVID-19 vaccines among pregnant women in Vietnam

AUTHOR(S)
Long Hoang Nguyen; Men Thi Hoang; Lam Duc Nguyen (et al.)

Published: August 2021   Journal: Tropical Medicine & International Health

The aim of this study was to assess acceptance of COVID-19 vaccination and the willingness to pay (WTP) for it, and investigate associated factors among pregnant women in Vietnam.Cross-sectional survey of pregnant women in two obstetric hospitals in Hanoi and Ca Mau provinces, Vietnam. Data on acceptance and WTP for COVID-19, demographic characteristics, maternal characteristics, and risk perceptions toward COVID-19 were collected. Multivariate logistic and linear regression models were performed to identify factors associated with the acceptance and WTP for the vaccine.

Pediatric and parents' attitudes towards COVID-19 vaccines and intention to vaccinate for children

AUTHOR(S)
Soo-Han Choi; Yoon Hee Jo; Kyo Jin Jo (et al.)

Published: August 2021   Journal: Journal of Korean Medical Science

Coronavirus disease 2019 (COVID-19) vaccination is necessary to reach herd immunity and essential for mitigating the spread of the pandemic. In May 2021, the US FDA and the EU have expanded the emergency use authorization for a COVID-19 vaccine to children aged 12 to 15. The aim of this study was to investigate parental acceptability of COVID-19 vaccination for their children, factors affecting their acceptability, and children's perceptions of COVID-19 vaccines in Republic of Korea. A questionnaire survey at two tertiary hospitals was conducted from May 25, 2021 to June 3, 2021. Subjects were parents having children under 18 years and children aged 10–18 years.

COVID-19 vaccination during pregnancy: coverage and safety

AUTHOR(S)
Helena Blakeway; Smriti Prasa; Erkan Kalafat (et al.)

Published: August 2021   Journal: American Journal of Obstetrics and Gynecology

Concerns have been raised regarding a potential surge of COVID-19 in pregnancy, secondary to rising numbers of COVID-19 in the community, easing of societal restrictions, and vaccine hesitancy. Even though COVID-19 vaccination is now offered to all pregnant women in the UK, there are limited data on its uptake and safety. This was a cohort study of pregnant women who gave birth at St George’s University Hospitals NHS Foundation Trust, London, UK, between March 1st and July 4th 2021. The primary outcome was uptake of COVID-19 vaccination and its determinants. The secondary outcomes were perinatal safety outcomes.

Safety of components and platforms of COVID-19 vaccines considered for use in pregnancy: a rapid review

AUTHOR(S)
Agustín Ciapponi; Ariel Bardach; Agustina Mazzoni (et al.)

Published: August 2021

Rapid assessment of COVID-19 vaccine safety during pregnancy is urgently needed. This study conducted a rapid systematic review, to evaluate the safety of COVID-19 vaccines selected by the COVID-19 Vaccines Global Access-Maternal Immunization Working Group in August 2020, including their components and their technological platforms used in other vaccines for pregnant persons. It searched literature databases, COVID-19 vaccine pregnancy registries, and explored reference lists from the inception date to February 2021 without language restriction. Pairs of reviewers independently selected studies through COVIDENCE, and performed the data extraction and the risk of bias assessment. Discrepancies were resolved by consensus.

COVID-19 vaccination in Chinese children: a cross-sectional study on the cognition, psychological anxiety state and the willingness toward vaccination

AUTHOR(S)
Jin Yanga; Ting Zhanga; Weiran Qi (et al.)

Published: July 2021   Journal: Human Vaccines & Immunotherapeutics
It is important to understand the cognition, willingness, and psychological anxiety state of Chinese guardians toward COVID-19 vaccination for their children to predict the future vaccination rate and to help the design of policies that aim to expand the population with immunity against COVID-19. This study collected data with a professional vaccination registration platform for children named “Xiao Dou Miao” in February 2021. The psychological anxiety state of the guardians was self-evaluated using the psychological anxiety scale. Factors that might influence the willingness of guardians to vaccinate their children were identified using logistic regression analysis. This study included 12,872 questionnaires with 70.9% of guardians showing willingness to vaccinate their children.
COVID-19 in Ghana: challenges and countermeasures for maternal health service delivery in public health facilities

AUTHOR(S)
Faith Agbozo; Albrecht Jahn

Published: July 2021   Journal: Reproductive Health
This study provides a situational update on COVID-19 in Ghana, the seventh African country reporting the most cases. Some modifications occurring within the health system to curtail the outbreak and its potential impact on the delivery of antenatal care services are also highlighted. With the discovery of the Delta variant in Ghana, the current attention is to prevent a third wave of infection, and also control and manage existing cases. Efforts to procure vaccines, vaccinate special populations and sensitize the public on the implications of vaccine hesitancy are ongoing.
Impact of the COVID-19 pandemic on routine childhood immunisation in Colombia

AUTHOR(S)
José Moreno-Montoya; Silvia Marcela Ballesteros; Jaid Constanza Rojas Sotelo (et al.)

Published: July 2021   Journal: Archives of Disease in Childhood

This article aims to assess the impact of the COVID-19 pandemic on routine childhood vaccination coverage in Colombia by age group, rural/urban residence, state and vaccine type. It is an ecological study of official monthly vaccination records.

Parental plans to vaccinate children for COVID-19 in New York city

AUTHOR(S)
Chloe A. Teasdale; Luisa N. Borrell; Yanhan Shen (et al.)

Published: July 2021   Journal: Vaccine
Once COVID-19 vaccines are approved for children < 12 years of age, high pediatric vaccination coverage will be needed to help minimize the public health threat from the SARS-CoV-2 epidemic. We conducted an online survey of 1,119 parents and caregivers of children ≤ 12 years in New York City from March 9 to April 11, 2021. Among parents surveyed, 61.9% reported plans to vaccinate their youngest child for COVID-19, 14.8% said they do not plan to vaccinate their child and 23.3% were unsure. Female and non-Hispanic Black parents were least likely to report plans to vaccinate their children. Safety, effectiveness and perceptions that children do not need vaccination were the primary reasons for vaccine hesitancy/resistance. Parents who have or will vaccinate themselves were significantly more likely to report they would vaccinate their children.
Parental perspectives on immunizations: impact of the COVID-19 pandemic on childhood vaccine hesitancy

AUTHOR(S)
Kaidi He; Wendy J. Mack; Michael Neely (et al.)

Published: July 2021   Journal: Journal of Community Health
Childhood vaccine hesitancy has been studied extensively before the COVID-19 pandemic. The pandemic presented new barriers to pediatric vaccinations. Furthermore, the development of COVID-19 vaccines has complicated factors underlying vaccine hesitancy. This study performed a cross-sectional mobile phone-based survey at Children’s Hospital Los Angeles querying parents regarding perspectives on vaccines before and during the pandemic. Its primary aim was to understand the impact of the pandemic on routine childhood vaccine hesitancy. Secondarily, it examined intent to vaccinate, COVID-19 vaccine hesitancy, and key contributing demographic factors.
361 - 375 of 468

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