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Children and COVID-19 Research Library

UNICEF Innocenti's curated library of COVID-19 + Children research

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Parental and pediatricians' attitudes towards COVID-19 vaccination for children: results from nationwide samples in Greece

Evangelia Steletou; Theodoros Giannouchos; Ageliki Karatza (et al.)

Published: August 2022   Journal: Children
Although many studies have examined factors associated with COVID-19 vaccination and healthcare professionals’ attitudes towards vaccines, less is known about parents’ and pediatricians’ attitudes towards COVID-19 vaccination for children. Using two cross-sectional surveys from November to December 2021 in Greece, this study aimed to assess parental intention to vaccinate their 5 to 17 years old children against COVID-19 and to evaluate pediatricians’ attitudes towards children’s vaccination against COVID-19. Overall, 439 parents and 135 pediatricians participated.
Disruptions to routine childhood vaccinations in low- and middle-income countries during the COVID-19 pandemic: a systematic review

Alexandra M. Cardoso Pinto; Lasith Ranasinghe; Peter J. Dodd (et al.)

Published: August 2022   Journal: Frontiers in Pediatrics

The COVID-19 pandemic has disrupted routine childhood vaccinations worldwide with low- and middle-income countries (LMICs) most affected. This study aims to quantify levels of disruption to routine vaccinations in LMICs.  A systematic review (PROSPERO CRD42021286386) was conducted of MEDLINE, Embase, Global Health, CINAHL, Scopus and MedRxiv, on the 11th of February 2022. Primary research studies published from January 2020 onwards were included if they reported levels of routine pediatrics vaccinations before and after March 2020. Study appraisal was performed using NHLBI tool for cross-sectional studies. Levels of disruption were summarized using medians and interquartile ranges.

Parental decision and intent towards COVID-19 vaccination in children with asthma: an econometric analysis

Olivier Drouin; Pierre Fontaine; Yann Arnaud (et al.)

Published: August 2022   Journal: BMC Public Health

Vaccination will be instrumental in controlling the COVID-19 pandemic, and vaccination of children will be necessary to achieve herd immunity. Given that children with chronic health conditions may be at increased risk of COVID-19, it is crucial to understand factors influencing parental decisions about whether to have their child vaccinated. The study objectives were to measure parental intent to have their child with asthma vaccinated against COVID-19 and identify the determinants of their vaccination decision. This study is based on a cross-sectional exploratory observational online survey assessing parents' risk perception in the context of COVID-19.

Vaccine effectiveness of CoronaVac against COVID-19 among children in Brazil during the Omicron period

Pilar T. V. Florentino; Flávia J. O. Alves; Thiago Cerqueira-Silva (et al.)

Published: August 2022   Journal: Nature Communications
Although severe COVID-19 in children is rare, they may develop multisystem inflammatory syndrome, long-COVID and downstream effects of COVID-19, including social isolation and disruption of education. Data on the effectiveness of the CoronaVac vaccine is scarce during the Omicron period. In Brazil, children between 6 to 11 years are eligible to receive the CoronaVac vaccine. This research conducted a test-negative design to estimate vaccine effectiveness using 197,958 tests from January 21, 2022, to April 15, 2022, during the Omicron dominant period in Brazil among children aged 6 to 11 years.
COVID-19 vaccine hesitancy among parents of children under five years in the United States

Celia B. Fisher; Elise Bragard; Rimah Jaber (et al.)

Published: August 2022   Journal: Vaccines
On 17 June 2022, the U.S. FDA authorized the Pfizer-BioNTech and Moderna COVID-19 (SARS-CoV-2) vaccines for emergency use (EUA) in children ages 6 months–4 years. Seroprevalence has increased during the current Omicron variant wave for children under 5 years, and the burden of hospitalization for this age group is similar or exceeds other pediatric vaccine-preventable diseases. Research following the October 2021 EUA for vaccines for children 5–11 indicates a high prevalence of parental vaccine hesitancy and low uptake, underscoring the urgency of understanding attitudes and beliefs driving parental COVID-19 vaccine rejection and acceptance for younger children. One month prior to FDA approval, in the present study 411 U.S. female guardians of children 1–4 years from diverse racial/ethnic, economic, and geographic backgrounds participated in a mixed method online survey assessing determinants of COVID-19 pediatric vaccine hesitancy.
SARS-CoV-2 infection in children and implications for vaccination

Jordan Nathanielsz; Zheng Quan Toh; Lien Anh Ha Do (et al.)

Published: August 2022   Journal: Pediatric Research
he COVID-19 pandemic caused by novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for more than 500 million cases worldwide as of April 2022. Initial estimates in 2020 found that children were less likely to become infected with SARS-CoV-2 and more likely to be asymptomatic or display mild COVID-19 symptoms. Our early understanding of COVID-19 transmission and disease in children led to a range of public health measures including school closures that have indirectly impacted child health and wellbeing. The emergence of variants of concern (particularly Delta and Omicron) has raised new issues about transmissibility in children, as preliminary data suggest that children may be at increased risk of infection, especially if unvaccinated. Global national prevalence data show that SARS-CoV-2 infection in children and adolescents is rising due to COVID-19 vaccination among adults and increased circulation of Delta and Omicron variants. To mitigate this, childhood immunisation programmes are being implemented globally to prevent direct and indirect consequences of COVID-19 including severe complications (e.g., MIS-C), debilitating long-COVID symptoms, and the indirect impacts of prolonged community and school closures on childhood education, social and behavioural development and mental health. This review explores the current state of knowledge on COVID-19 in children including COVID-19 vaccination strategies.
Parental perceptions and the 5C psychological antecedents of COVID-19 vaccination during the first month of omicron variant surge: a large-scale cross-sectional survey in Saudi Arabia

Shuliweeh Alenezi; Mohammed Alarabi; Ayman Al-Eyadhy (et al.)

Published: August 2022   Journal: Frontiers in Pediatrics

With the rapid surge of SARS-CoV-2 Omicron variant, this study aimed to assess parents' perceptions of the COVID-19 vaccines and the psychological antecedents of vaccinations during the first month of the Omicron spread.  A cross-sectional online survey in Saudi Arabia was conducted (December 20, 2021-January 7, 2022). Convenience sampling was used to invite participants through several social media platforms, including WhatsApp, Twitter, and email lists. This study utilized the validated 5C Scale, which evaluates five psychological factors influencing vaccination intention and behavior: confidence, complacency, constraints, calculation, and collective responsibility.

Hesitancy versus acceptability: An observational study for acceptance of COVID-19 vaccine among parents and guardians of children under 17 years age in South East Rajasthan

Ashutosh Sharma; Vinita Gupta; Anita Sharma (et al.)

Published: August 2022   Journal: Asian Journal of Medical Sciences

Vaccination against COVID-19 is necessary to reach herd immunity and essential for mitigating the spread. To establish herd immunity, the immunity generated by natural infection or vaccination must prevent onward transmission, not just clinical disease. However, several studies have shown that achieving herd immunity through natural infection might be difficult. The aim of the study is to enquire about parental acceptability for COVID-19 vaccination for their children, factors affecting acceptability, perceptions for pediatric COVID-19 vaccines.

COVID-19 vaccination intentions, concerns, and facilitators among US parents of children ages 6 months through 4 years

Aaron M. Scherer; Courtney A. Gidengil; Amber M. Gedlinske (et al.)

Published: August 2022   Journal: JAMA Network Open

Children aged 6 months through 4 years have become eligible for COVID-19 vaccination, but little is known about parental intentions regarding, concerns about, or facilitators to COVID-19 vaccination for this age group. To evaluate parental intentions, concerns, and facilitators for COVID-19 vaccination for children aged 6 months through 4 years and to help inform the US Centers for Disease Control and Prevention Advisory Committee on Immunization Practices’ deliberations and recommendations for COVID-19 vaccination for children aged 6 months through 4 years. This cross-sectional study fielded an online survey from February 2 to 10, 2022, among a nonprobability sample of US parents of children aged 6 months through 4 years who were recruited through Qualtrics using quota-based sampling for respondent gender, race and ethnicity, and child age group.

Pediatric off-label COVID-19 vaccination: the concerns of healthcare professionals in Pakistan

Sadia Shakeel; Shagufta Nesar; Ghazala Noor Nizami (et al.)

Published: August 2022   Journal: Vaccines
Global health authorities have emphasized the vital role of healthcare professionals (HCPs) as a reliable source of vaccination information for patients in primary care. However, HCPs are concerned whether COVID-19 vaccinations can be used off-label. Hence, the current study was conducted to assess their perspectives towards off-label COVID-19 immunization in children. The study tool, consisting of 40 items, was utilized to evaluate HCPs’ knowledge and attitudes towards the off-label use of the COVID-19 vaccine in children under 12 years of age. To assess the unfavorable attitudes regarding vaccinations, the Vaccination Attitudes Examination Scale was employed. Overall, 477 completed questionnaires were incorporated in the present study, with a response rate of 88.9%.
Cite this research | Open access | Vol.: 10 | Issue: 8 | No. of pages: 12 | Language: English | Topics: Health | Tags: COVID-19, immunization, immunization programmes, infectious disease, pandemic, vaccination, vaccination policies | Countries: Pakistan
Parental COVID-19 vaccine hesitancy in the United States

Jeanette B. Ruiz; Robert A. Bell

Published: August 2022   Journal: Public Health Reports

Little is known about parents’ willingness to vaccinate their children against COVID-19. This study assessed the prevalence of vaccine hesitancy among parents with a child or adolescent aged 12-15 years, examined predictors of parents’ COVID-19 vaccine hesitancy, their reasons for resisting a pediatric COVID-19 vaccine, and the correlation between parents’ intentions to vaccinate their child and the acceptance of a vaccine for themselves. A national online survey of 637 parents of a child or adolescent aged 12-15 years was conducted in March 2021, before COVID-19 vaccines had been approved for this age group. The study assessed univariate predictors of vaccine hesitancy, and it used logistic regression analysis to assess independent effects of variables on vaccine hesitancy.

The COVID-19 pandemic and children with PANS/PANDAS: an evaluation of symptom severity, telehealth, and vaccination hesitancy

Sarah L. O’Dor; J. S. Zagaroli; R. M. Belisle (et al.)

Published: August 2022   Journal: Child Psychiatry & Human Development
The current study assessed the impact of the COVID-19 pandemic on children with PANS/PANDAS, a condition characterized by sudden-onset obsessive-compulsive, tic, or restrictive eating symptoms following infection. It conducted an anonymous survey between February and June 2021 of 254 self-reported caregivers of minors with PANS/PANDAS. Caregivers answered questions regarding PANS/PANDAS symptoms, telehealth care, and intention to vaccinate their child against COVID-19. PANS/PANDAS symptoms during COVID-19 infections were assessed when applicable. Children’s OCD symptoms and coercive behaviors towards caregivers, along with the caregivers’ mental health, relationship satisfaction, and burden, were assessed using standardized questionnaires.
Childhood COVID-19 vaccine acceptance and preference from caregivers and healthcare workers in China: a survey experiment

Zhiyuan Hou; Kuimeng Song; Qian Wang (et al.)

Published: August 2022   Journal: Preventive Medicine
With approval of more COVID-19 vaccines for children, vaccine attributes may influence parental acceptance and choices. This study aimed to assess effects of vaccine attributes and information on herd immunity on childhood COVID-19 vaccine acceptance. A survey experiment was conducted with caregivers of children aged 6 months to 11 years old and health care workers (HCWs) in China from September 14 to November 18, 2021. Respondents were randomly assigned to receive differing information on herd immunity (> 80% of the entire population must be vaccinated; or no information). Respondents then completed eight discrete choice tasks to assess vaccine acceptance based on attributes. 2331 (90.07%) of 2588 surveyed caregivers and 1576 (92.71%) of 1700 surveyed HCWs would accept COVID-19 vaccination for children, respectively.
COVID-19 vaccine for children: vaccination willingness of parents and its associated factors: a network analysis

Julia Barbara Krakowczyk; Alexander Bäuerle; Lars Pape (et al.)

Published: July 2022   Journal: Vaccines
Different COVID-19 vaccines have been approved for underage children, so parents and caregivers currently face the decision of whether to vaccinate their children against COVID-19 or not. Due to the rather moderate vaccine acceptance among parents across different countries, the objective of the present study was to investigate the relationship between different psychological, demographic, and behavioral factors related to the acceptance of the COVID-19 vaccine for underage children among parents. In particular, vaccination attitudes, whether parents have been vaccinated against COVID-19 themselves, COVID-19 fear, attitude towards COVID-19 policy measures, governmental trust, subjective level of information, perceived risk of disease progression, and perceived risk of vaccine side effects were the variables of interest. The study adopted a cross-sectional study design, and the sample consisted of 2405 participants. A network analysis was conducted to investigate the associations and interconnection among these variables.
COVID-19 vaccination coverage among adolescents aged 12-17 years in three provinces of eastern China: a cross-sectional survey, 2021

Taishun Li; Ruowen Qi; Bingwei Chen (et al.)

Published: July 2022   Journal: Frontiers in Public Health
High vaccination coverage is essential to prevent and control the spread of the COVID-19 epidemic. Currently, the real-world acceptance of COVID-19 vaccines among adolescents aged 12–17 years in China has not been reported. We aimed to assess the acceptance rate of COVID-19 vaccination among adolescents in eastern China and to identify factors associated with the intention to get vaccinated against COVID-19. A cross-sectional questionnaire survey among adolescents from three provinces in the eastern part of China was conducted from 16 August to 28 October 2021. The questionnaires were distributed to 2,100 students, and 2,048 students completed the questionnaires.
46 - 60 of 379

UNICEF Innocenti's Children and COVID-19 Library is a database collecting research from around the world on COVID-19 and its impacts on children and adolescents.


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