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Children and COVID-19 Research Library

UNICEF Innocenti's curated library of COVID-19 + Children research

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46 - 60 of 468
CARD (Comfort Ask Relax Distract) for community pharmacy vaccinations in children: effect on immunization stress-related responses and satisfaction

Anna Taddio; James Morrison; Molly Yang (et al.)

Published: November 2022   Journal: Canadian Pharmacists Journal
CARD (Comfort Ask Relax Distract) is a vaccine delivery program demonstrated to reduce pain, fear and associated immunization stress-related responses (ISRR) in children undergoing vaccinations at school. This study evaluated CARD’s clinical impact when integrated into community pharmacy–based pediatric vaccinations. This was a before-and-after CARD implementation study in 5 independent pharmacies offering COVID-19 vaccinations to children aged 5-11 years. No changes were made to practices in the “before” phase. CARD interventions were integrated in the “after” phase (e.g., children prepared a coping plan using a checklist, distraction toolkits were placed in waiting and vaccination spaces, vaccinations were performed with privacy, needles were obscured). Children self-reported ISRR, including fear, pain and dizziness during vaccination, and both children and parents/caregivers (herein, parents) compared the child’s experience to their last needle (better, same, worse). In the “after” phase, parents and children reported how much CARD helped (not at all, a little bit, a moderate amount, a lot).
Determinants of the willingness of medical staff to vaccinate their children with a booster dose of the COVID-19 vaccine in Taizhou, China

Li-Li Huang; Tao-Hsin Tung; Yan-Hong Jiang (et al.)

Published: November 2022   Journal: Human Vaccines & Immunotherapeutics
The study aimed to determine the willingness of medical staff to have their children vaccinated with a COVID-19 booster in Taizhou, China. From March 21 to April 19, 2022, an online questionnaire survey was conducted to assess the willingness of medical staff to vaccinate their children with a booster dose of the COVID-19 vaccine. Of the 1,252 medical staff in a tertiary grade hospital in Taizhou who were invited to answer the structured questionnaire, 514 (41.1%) samples had valid information for further data analysis. Four hundred thirty-seven medical staff (85.0%) were willing to have their children receive vaccine boosters. After adjustments for confounding factors, the opinion (‘Do you think your child needs a booster vaccination against COVID-19?’) (yes vs. no, OR = 6.91, 95% CI: 3.29–14.54), the viewpoint (‘What are your thoughts the effectiveness of COVID-19 vaccine boosters for children?’ (≥12 vs. <12, OR = 13.81, 95% CI: 4.03-), and the attitude (‘Your attitude to whether your child is boosting the Covid-19 vaccine?’) (yes vs. no, OR = 4.66, 95% CI: 2.30–9.44) were significantly associated with their willingness to have their children receive a COVID-19 vaccine booster.
Willingness and attitudes of parents towards COVID-19 vaccines for children in Vietnam

Thi Loi Dao; Hue Vu Thi; Philippe Gautret (et al.)

Published: November 2022   Journal: Journal of Communication in Healthcare

With an increasing need for COVID-19 vaccination around the globe, we aim to investigate willingness and attitudes of parents regarding COVID-19 vaccines for children in Vietnam. A 24-item online survey was conducted among 602 parents and legal guardians of children under 18 years of age.

Efficacy, effectiveness and safety of vaccines against COVID-19 for children aged 5-11 years: a living systematic review with meta-analysis

Vanessa Piechotta; Waldemar Siemens

Published: November 2022   Journal: Lancet
To date, more than 628 million confirmed SARS-CoV-2 infections were recorded globally. Highest incidences were usually observed in school-aged children. The aim of this living systematic review is to evaluate vaccine efficacy/effectiveness (VE) and safety of COVID-19 vaccines approved in the European Union for children aged 5-11 years. In this version, we included studies of any design identified through searching the COVID-19 L·OVE (Living OVerview of Evidence) platform up to 13 September 2022. We assessed risk of bias and rated the certainty of evidence (CoE) using GRADE.
COVID-19 vaccination in pediatric population with transfusion dependent thalassemia

Vineeta Singh; Nirali F. Sanghvi; Priyanka Aggarwal (et al.)

Published: November 2022   Journal: Pediatric Hematology Oncology Journal

Similar to normal pediatric population, children with thalassemia are at risk of acquiring COVID-19 infection. Theoretically, they are at higher risk of severe infection because of comobidities associated with chronic transfusions. This study is an attempt to find out the awareness of COVID-19 vaccination in transfusion dependent thalassemia patients attending thalassemia clinic at our institute. It is an observational study consisting of 21 children with transfusion dependent thalassemia from 12 years to 18 years of age attending the thalassemia clinic between May to July 2022. Awareness and the status of COVID-19 vaccination in children and their families was assessed using a questionnaire.

The impact of the COVID-19 pandemic on parents' perceptions and acceptance of routine childhood vaccination in Canada: a national longitudinal study

Robin M. Humble; Shannon D. Scott; Eve Dubé (et al.)

Published: November 2022   Journal: Vaccine

A decline in routine vaccination was reported by some countries early in the COVID-19 pandemic. In the context of the pandemic, determinants of routine childhood vaccination may have changed. Changes over time in parents’ perceptions of routine vaccines and intentions for their children during the pandemic have not been fully explored. Understanding changes provides opportunities to promote routine childhood vaccines and address factors that may compromise parents’ acceptance. This is a longitudinal analysis of two sequential national surveys during the pandemic (Dec 2020 and Oct/Nov 2021) to assess changes over time in Canadian parents’ perceptions of routine childhood vaccines, intentions to vaccinate, access for their children ≤ 17 years, and differences among sociodemographic characteristics. McNemar-Bowker tests were used to determine changes in parents’ responses collected at two time points.

Cite this research | Open access | Vol.: 41 | Issue: 2 | No. of pages: 407-415 | Language: English | Topics: Health | Tags: COVID-19 response, immunization, immunization programmes, lockdown, parents, social distance, vaccination, vaccination policies | Countries: Canada
The influence of counseling and storytelling method on the anxiety levels of primary school children to receive COVID-19 vaccine

Anita Dyah Listyarini; Maftuhah Khoirotun Nisa; Icca Narayani Pramudaningsih (et al.)

Published: November 2022   Journal: Journal of Pharmaceutical Negative Results,
The World Health Organization, WHO explains that sadness and anxiety are the most common mental health problems. Anxiety for children occurs due to the COVID-19 vaccination program by the government may cause uncooperative attitudes. Thus, this situation may lower the children's effectiveness to join learning activities. This research analyzed the influence of counseling with the storytelling method on the anxiety of school learners to receive COVID-19 vaccination in Primary School 03 Bulungcangkring. This research applied a quasi-experimental research design with a pre- and post-test control group approach. The sample consisted of 58 respondents taken with the proportionate stratified random sampling technique. Each group, the intervention, and control group, consisted of 29 respondents. The researchers analyzed the data with paired t-test.
Factors associated with COVID‑19 vaccine uptake among adolescents and young adults recently diagnosed with cancer

Gary Kwok; Samantha Reese; Sanjana Dugad (et al.)

Published: November 2022   Journal: Journal of Adolescent and Young Adult Oncology
Adolescents and young adults (AYAs) recently diagnosed with cancer are medically vulnerable but little is known about vaccine uptake/intent in this group. AYAs reported on their COVID-19 vaccine uptake/intent. Logistic regression models examined factors associated with vaccine uptake. Higher education (adjusted odds ratio [aOR] = 1.9, 95% confidence interval [CI]: 1.0–3.5) and knowing someone diagnosed with COVID-19 (aOR = 7.2, 95% CI: 1.6–33.5) were associated with increased vaccine uptake. Prior personal diagnosis of COVID-19 (aOR = 0.1, 95% CI: 0.1–0.7) was associated with lower odds of uptake. Targeted interventions may be needed to improve uptake among this group. (ClinicalTrials.gov Identifier: NCT04585269).
Safety of COVID-19 Pfizer-BioNtech (BNT162b2) mRNA vaccination in adolescents aged 12-17 years: a systematic review and meta-analysis

Patrick D. M. C. Katoto; Amanda S. Brand; Liliane N. Byamungu (et al.)

Published: November 2022   Journal: Human Vaccines & Immunotherapeutics
The COVID-19 pandemic has severely affected adolescents. Safe and effective vaccines are pivotal tools in controlling this pandemic. We reviewed the safety profile of the BNT162b2 COVID-19 vaccine in adolescents using mostly real-world data to assist decision-making. We used random-effects model meta-analysis to derive pooled rates of single or grouped adverse events following immunization (AEFI) after each primary and booster dose, as well as after combining all doses. Reporting on over one million participants with safety data were included.
Effectiveness of the booster of SARS-CoV-2 vaccine among Japanese adolescents: a cohort study

Yoshika Saito; Kana Yamamoto; Morihito Takita (et al.)

Published: November 2022   Journal: Vaccines
Vaccination is effective in preventing COVID-19-related hospitalization among all age groups, but there is limited evidence on the effectiveness of the booster of the SARS-CoV-2 vaccine among adolescents. This study analyzed the data on the status of SARS-CoV-2 infection and their vaccination profiles in adolescents aged 13–18 years in Soma city (Fukushima, Japan) (n = 1835) from 14 May to 15 June 2022. The crude incidence rate and 95% confidence interval were calculated with the negative-binomial regression model after classifying the immunization status. The crude effectiveness of a booster administration to prevent infections was estimated as 86.4% (95% confidence interval: 57.2–95.7) when compared with the primary vaccination alone.
COVID-19 vaccine coverage disparities in rural and farm children

Jeffrey J. VanWormer; Gabriella Alicea; Bryan P. Weichelt (et al.)

Published: November 2022   Journal: Vaccine

The risks of severe outcomes associated with SARS-CoV-2 (COVID-19) are elevated in unvaccinated individuals. It remains crucial to understand patterns of COVID-19 vaccination, particularly in younger and remote populations where coverage often lags. This study examined disparities in COVID-19 vaccine coverage in farm children and adolescents. A cross-sectional analysis was conducted in patients of the Marshfield Clinic Health System (MCHS) in Wisconsin. The sample included children/adolescents age 5-17 years who were eligible for COVID-19 vaccine initiation for ≥ 90 days (as of September 30, 2022), stratified by those who lived vs did not live on a farm. Outcomes included COVID-19 vaccine initiation, series completion, and booster receipt. Multivariable regression was used to examine associations between COVID-19 vaccination and farm, as well as rural and non-rural, residence.

Speaking truth to power: Legal scholars as survivors and witnesses of the Covid-19 maternal mortality in Brazil

Gabriela Rondon; Debora Diniz; Juliano Zaiden Benvindo

Published: November 2022   Journal: International Journal of Constitutional Law
The Covid-19 health emergency has placed special demands on legal scholars, particularly on those based in the Global South. Brazil has been one of the epicenters of the pandemic, with over 680,000 deaths as of August 2022. Our narrative emerges from the duality of our positions amid a national tragedy—we are at the same time survivors of the collective threat of a would-be autocrat and a Covid-19-denialist government, and witnesses to how our preexisting privileges put us in a position of readiness “to speak truth to power.” Speaking truth to power means not only to exercise an independent spirit of analysis and judgment with respect to power, but also to interpellate power openly about its wrongdoings. We understand that our responsibility as legal scholars is to embrace the urgency of the moment—to expand our research agendas beyond our previous academic trajectories and work to mitigate situations of rights violations. It also means that our work as legal scholars has had to transcend the traditional academic spaces. We have positioned ourselves as advocates and litigators for those most affected by the pandemic, in particular vulnerable women. In this article, we share one of our key initiatives during the pandemic—a constitutional lawsuit to demand the right of pregnant and postpartum people to access Covid-19 vaccines.
Parents' attitudes toward childhood vaccines and COVID-19 vaccines in a Turkish pediatric outpatient population

Nihal Durmaz; Murat Suman; Murat Ersoy (et al.)

Published: November 2022   Journal: Vaccines
Vaccination hesitancy (VH) is an important public health issue. The determinants of parental decisions on whether to vaccinate their children are multidimensional and need to be carefully considered in the COVID-19 era. Our study aims to investigate the prevalence of VH among parents, parents’ use of social media, and their attitudes toward the COVID-19 vaccine upon vaccine refusal. Materials and methods: Our participants were the parents of children admitted to hospitals in three different cities in Turkey between September 2021 and December 2021. The parents were asked to complete sociodemographic data and their attitudes toward COVID-19 diseases, the Parental Attitudes Toward Childhood Vaccines (PACV) scale, and the Attitudes Toward COVID-19 Vaccine (ATV-COVID-19) scale. Participants were categorized as “non-hesitant”, with a score of <50, and “hesitant”, with a score of ≥50.
Cite this research | Open access | Vol.: 10 | Issue: 11 | No. of pages: 13 | Language: English | Topics: Health | Tags: COVID-19, immunization, immunization programmes, infectious disease, pandemic, parents, vaccination, vaccination policies | Countries: Turkey
Determinants of parents' intention to vaccinate their children aged 12–17 years against NST COVID-19 in North Kivu (DRC)

Stephane Hans Bateyi Mustafa; Michel Kabamba; Clément Bula Baswayi (et al.)

Published: November 2022   Journal: IJRDO - Journal Of Health Sciences And Nursing

Vaccinating children against COVID-19 is an essential public health strategy in order to reach herd immunity and prevent illness among children and adults. Parents are facing tremendous stress in relation to the COVID - 19 pandemic and the effectiveness of the COVID-19 vaccination program for children. In this study, we aimed to investigate parents’ willingness to vaccinate their children against COVID-19 in North Kivu province (DRC). A cross-sectional survey between 1 December 2021to 20 January 2022 in six health zones (Goma, Karisimbi, Butembo, Beni, Kamango, and Katwa) was conducted in the province of North Kivu. In each health zone, we selected five clusters (Health area) using the method of probabilistic selection proportional to population size. In total, 522 parents participated in our study.

Parental willingness for COVID-19 vaccination among children aged 5 to 11 years in Riyadh City, Saudi Arabia: a cross-sectional study

Awad Mohammed Al-Qahtani; Basheerahmed Abdulaziz Mannasaheb; Mohammed Ashique K. Shaikh (et al.)

Published: November 2022   Journal: Vaccines
To manage the COVID-19 outbreak, the WHO recommends adult and child vaccination. Vaccine skepticism has been a major worldwide health concern for decades, and the situation is worsening. The primary purpose of this study was to investigate parental willingness to vaccinate their children (aged 5 to 11 years) against COVID-19 and to describe its relationship with attitude, barriers, facilitators, and sources of knowledge regarding the vaccine. Methods: From February to March 2022, a community-based cross-sectional survey was undertaken among the parents of Riyadh city, Saudi Arabia. We employed a convenient sampling procedure to gather the required sample. Using the Raosoft sample size calculator, a minimum sample size of 385 was determined based on a 95% confidence level, a 5% margin of error, and a 5% precision level. The data were analyzed using version 26 of SPSS. A p-value less than 0.05 was judged statistically significant. The Chi-square test and likelihood ratio were utilized to describe the relationship between socio-demographic characteristics, driving factors, and COVID-19 vaccine hesitancy. Vaccine hesitancy associated factors were identified using multivariate binary logistic regression. A total of 528 replies were received.
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UNICEF Innocenti's Children and COVID-19 Library is a database collecting research from around the world on COVID-19 and its impacts on children and adolescents.


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