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Children and COVID-19 Research Library

UNICEF Innocenti's curated library of COVID-19 + Children research

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106 - 120 of 179
Safety, tolerability, and immunogenicity of an inactivated SARS-CoV-2 vaccine (CoronaVac) in healthy children and adolescents: a double-blind, randomised, controlled, phase 1/2 clinical trial

AUTHOR(S)
Bihua Han; Yufei Song; Changgui Li (et al.)

Published: June 2021   Journal: The Lancet Infectious Diseases
A vaccine against SARS-CoV-2 for children and adolescents will play an important role in curbing the COVID-19 pandemic. This study aimed to assess the safety, tolerability, and immunogenicity of a candidate COVID-19 vaccine, CoronaVac, containing inactivated SARS-CoV-2, in children and adolescents aged 3–17 years.
Parental psychological distress and attitudes towards COVID-19 vaccination: a cross-sectional survey in Shenzhen, China

AUTHOR(S)
Yucheng Xu; Ruiyin Zhang; Zhifeng Zhou

Published: June 2021   Journal: Journal of Affective Disorders

Parental attitudes towards the vaccines play a key role in the success of the herd immunity for the COVID-19. Psychological health seems to be a controversial determinant of vaccine hesitancy and remains to be investigated. This study attempted to measure parental psychological distress, attitudes towards the COVID-19 vaccine, and to explore the potential associations. An online survey using convenience sampling method was conducted among parents within the school public health network of Shenzhen. Demographic information and attitudes towards COVID-19 vaccination were collected. The Patient Health Questionnaire (PHQ-4) was applied to measure psychological distress.

Methodologic approaches in studies using real-world data (RWD) to measure pediatric safety and effectiveness of vaccines administered to pregnant women: a scoping review

AUTHOR(S)
Tamar Lasky; Ann W. McMahon; Wei Hua (et al.)

Published: June 2021   Journal: Vaccine

This scoping review mapped studies using real-world data (RWD) to measure pediatric safety and effectiveness of vaccines administered to pregnant women. In the US, two vaccines are recommended for all pregnant women to prevent illness in the infant: inactivated influenza vaccine (recommended since 2004), and the combined tetanus-diphtheria-acellular pertussis (Tdap) vaccine (recommended since 2013). This scoping review maps the studies conducted to date that address questions about pediatric safety and effectiveness of vaccines administered during pregnancy and provides a knowledge base for evaluating the use of RWD to study this issue.

Cite this research | Open access | Vol.: 39 | Issue: 29 | No. of pages: 3814-3824 | Language: English | Topics: Health | Tags: COVID-19, infectious disease, maternal and child health, pregnancy, pregnant women, vaccination, vaccination policies | Countries: United States
Maternal vaccines during the Covid-19 pandemic: a qualitative interview study with UK pregnant women

AUTHOR(S)
Amberly Brigden; Anna Davies; Emily Shepherd (et al.)

Published: June 2021   Journal: Midwifery

There is suboptimal uptake of recommended maternal vaccines (pertussis and influenza) during pregnancy in the UK. The Covid-19 pandemic has impacted healthcare services, and potentially vaccine coverage, and brought the need for new vaccines to be tested and rolled out. This study aims to explore: i) the impact of the Covid-19 pandemic on pregnant women's access to, and attitudes towards, routine maternal vaccines and; ii) women's attitudes towards testing Covid-19 vaccines on pregnant women and their personal willingness to take part in such a trial.

Impact and projections of the COVID-19 epidemic on attendance and routine vaccinations at a pediatric referral hospital in Cameroon

AUTHOR(S)
D. Chelo; F. Nguefack; D. Enyama (et al.)

Published: June 2021   Journal: Archives de Pédiatrie

At the beginning of March 2020, Cameroon experienced its first cases of infection with the new coronavirus (SARS-COV-2). Very quickly, there was a drop in the rate of hospital attendance. The purpose of this study was to observe the variations in the uptake of pediatric consultations and vaccinations in a pediatric hospital. A descriptive and retrospective cross-sectional study was carried out using consultation and vaccination statistics from a pediatric hospital in the city of Yaoundé, political capital of Cameroon, from January 2016 to May 2020.

High risk, low priority: refugees excluded from COVID-19 vaccine rollout

AUTHOR(S)
Delphine Vallette; Nina Nepesova; Natalia Korobkova (et al.)

Institution: World Vision
Published: June 2021
The COVID-19 crisis has affected everyone, but people living on the world’s margins, including the forcibly displaced who face some of the highest risks but remain the lowest priority in national and global responses to the pandemic. Yet, vaccine justice is not only essential to protect the most at risk but it is also critical to prevent even more catastrophic impact globally. The pandemic will not end anywhere until it ends everywhere
Emerging and re-emerging infections in children: COVID/ MIS-C, Zika, Ebola, Measles, Varicella, Pertussis ... immunizations

AUTHOR(S)
Carol C. Chen; Anne Whitehead

Published: June 2021   Journal: Emergency Medicine Clinics of North America

Although the disease caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) seems to be less common and less severe in children, it remains unclear what role pediatric populations play in the spread of the virus. The understanding of multisystem inflammatory syndrome in children associated with SARS-CoV-2 infection is continuing to evolve, and guidelines for evaluation and treatment may depend on local and institutional recommendations. Emergency providers can play an important role in advocating for public health in the form of vaccine advocacy and education. While still rare, emergency providers must also consider nonendemic, mostly tropical infections in children presenting with fever who are recently returning from international travel.

COVID-19 vaccine acceptance and its associated factors among pregnant women attending antenatal care clinic in Southwest Ethiopia: institutional-based cross-sectional study

AUTHOR(S)
Ayenew Mose; Alex Yeshaneh

Published: June 2021   Journal: International Journal of General Medicine
COVID-19 vaccination is a safe and effective approach to control the pandemic and to prevent its associated morbidity and mortality. To our knowledge, there is no study conducted to assess the prevalence of COVID-19 vaccine acceptance among pregnant women in Ethiopia. Therefore, the main objective of this study was to assess the prevalence of COVID-19 vaccine acceptance and its associated factors among pregnant women attending antenatal care clinic in Southwest Ethiopia.
COVID-19 related immunization disruptions in Rajasthan, India: a retrospective observational study

AUTHOR(S)
Radhika Jain; Ambika Chopra; Camille Falézan (et al.)

Published: June 2021   Journal: Vaccine
Governments around the world suspended immunization outreach to control COVID-19 spread. Many have since resumed services with an emphasis on catch-up vaccinations. This paper evaluated immunization disruptions during India’s March-May 2020 lockdown and the extent to which subsequent catch-up efforts reversed them in Rajasthan, India.
Coronavirus disease and vaccination during pregnancy and childbirth: a review of the Israeli perspective and experience

AUTHOR(S)
Eran Hadar; Sarah Dollinger; Arnon Wiznitzer

Published: June 2021   Journal: The Journal of Maternal-Fetal & Neonatal Medicine

This paper aims to discuss selected aspects of our local and national experience in treating and vaccinating pregnant women with SARS-CoV-2 infection and COVID-19 disease. A comprehensive, retrospective review of COVID-19 parturients in our center as well as a detailed literature review of several aspects from the groundbreaking research done in Israel to investigate the direct obstetrical impact of COVID-19, indirect effect of the lockdown measures and the vaccination effort among pregnant women.

A reasoned approach towards administering COVID-19 vaccines to pregnant women

AUTHOR(S)
Angsumita Pramanick; Abhiram Kanneganti; Jing Lin Jeslyn Wong (et al.)

Published: June 2021   Journal: Prenatal Diagnosis

There are over 50 SARS-CoV-2 candidate vaccines undergoing Phase II and III clinical trials. Several vaccines have been approved by regulatory authorities and rolled out for use in different countries. Due to concerns of potential teratogenicity or adverse effect on maternal physiology, pregnancy has been a specific exclusion criterion for most vaccine trials with only two trials not excluding pregnant women. Thus, other than limited animal studies, gradually emerging development and reproductive toxicity data, and observational data from vaccine registries, there is a paucity of reliable information to guide recommendations for the safe vaccination of pregnant women. Pregnancy is a risk factor for severe COVID-19, especially in women with comorbidities, resulting in increased rates of preterm birth and maternal morbidity.

COVID-19 vaccination in pregnancy and postpartum

AUTHOR(S)
Eleonora Brillo; Valentina Tosto; Sandro Gerli

Published: June 2021   Journal: The Journal of Maternal-Fetal & Neonatal Medicine

This study aims to identify whether COVID-19 vaccines should be administered in pregnant and breastfeeding women by reviewing the guidance and other evidence. It reviewed the COVID-19 vaccination guidance for pregnant and breastfeeding women published to date and evidence from preclinical experimental and observational clinical studies, and discuss their implications.

Impact of the COVID-19 pandemic on the provision of routine childhood immunizations in Ontario, Canada

AUTHOR(S)
Pierre-Philippe Piché-Renaud; Catherine Ji; Daniel S. Farrar (et al.)

Published: June 2021   Journal: Vaccine

The COVID-19 pandemic has a worldwide impact on all health services, including childhood immunizations. In Canada, there is limited data to quantify and characterize this issue. We conducted a descriptive, cross-sectional study by distributing online surveys to physicians across Ontario. The survey included three sections: provider characteristics, impact of COVID-19 on professional practice, and impact of COVID-19 on routine childhood immunization services. Multivariable logistic regression identified factors associated with modification of immunization services.

Parents’ willingness and attitudes concerning the COVID-19 vaccine: a cross-sectional study

AUTHOR(S)
Meltem Yılmaz; Mustafa Kursat Sahin (et al.)

Published: May 2021   Journal: The International Journal of Clinical Practice

This study aimed to evaluate the parents’ willingness and attitudes concerning the COVID-19 vaccine. This cross-sectional study was performed using a self-administered online survey, covering parents’ and their children's characteristics, parents’ willingness and attitudes towards the COVID-19 vaccine. A total of 1035 parents participated.

Impact that the COVID-19 pandemic on routine childhood vaccinations and challenges ahead: a narrative review
Published: May 2021   Journal: Acta Paediatrica

This study aim to document the decline in vaccination coverage in the first months of 2020 as an indirect effect of the COVID-19 pandemic. A literature review in medical databases was performed. Overall, 143 articles were initially retrieved, out of which 48 were selected and included in the review.

106 - 120 of 179

UNICEF Innocenti's Children and COVID-19 Library is a database collecting research from around the world on COVID-19 and its impacts on children and adolescents.

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COVID-19 & Children: Rapid Research Response

UNICEF Innocenti is mobilizing a rapid research response in line with UNICEF’s global response to the COVID-19 crisis. The initiatives we’ve begun will provide the broad range of evidence needed to inform our work to scale up rapid assessment, develop urgent mitigating strategies in programming and advocacy, and preparation of interventions to respond to the medium and longer-term consequences of the COVID-19 crisis. The research projects cover a rapid review of evidence, education analysis, and social and economic policies.