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Children and COVID-19 Research Library

UNDER DEVELOPMENT UNICEF Innocenti's curated library of COVID-19 + Children research

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Journal article

Newborns of COVID-19 mothers: short-term outcomes of colocating and breastfeeding from the pandemic’s epicenter

AUTHOR(S)
Uday P. Patil; Sheela Maru; Parvathy Krishnan (et al.)

Published: June 2021

The United States of America has been severely affected by the COVID-19 pandemic during the spring of 2020. The largely immigrant and densely populated neighborhoods of Queens, NY, served by a large public hospital, Elmhurst Hospital Center (NYC H+H/Elmhurst), have emerged as one of the hardest-hit areas in the country. Newborns are at high risk of acquiring severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from their infected mothers who delivered during this period; however, data remains limited. This article aims to describe the unique experience from our Baby Friendly hospital at the epicenter of the COVID-19 pandemic.

Journal article

Adherence to masking requirement during the COVID-19 pandemic by early elementary school children

AUTHOR(S)
Geoffrey E. Mickells; Janet Figueroa; Kelly Withers West (et al.)

Published: May 2021 Journal: Journal of School Health

Top public health experts and organizations strongly recommend universal masking for children older than 2 years old during the COVID-19 pandemic, but speculate it may be difficult for young children. This study sought to assess the usage of cloth face masks in grades pre-K-2 and identify associated characteristics and adverse events. It is the first data to assess mask wearing by young children in school. This online, prospective, observational, survey in multiple schools within a single school district in a major metropolitan area measured adherence to face covering mandates by students in grades pre-K-2 as measured by percentage of day with appropriate face mask wearing per report via daily teacher surveys for the first 4 weeks of school.

Journal article

Parents’ willingness and attitudes concerning the COVID-19 vaccine: a cross-sectional study

AUTHOR(S)
Meltem Yılmaz; Mustafa Kursat Sahin (et al.)

Published: May 2021 Journal: The International Journal of Clinical Practice

This study aimed to evaluate the parents’ willingness and attitudes concerning the COVID-19 vaccine. This cross-sectional study was performed using a self-administered online survey, covering parents’ and their children's characteristics, parents’ willingness and attitudes towards the COVID-19 vaccine. A total of 1035 parents participated.

Commentaries and Think Pieces

Parents’ intention to get vaccinated and to have their child vaccinated against COVID-19: cross-sectional analyses using data from the KUNO-Kids health study

AUTHOR(S)
Susanne Brandstetter; Merle M. Böhmer; Maja Pawellek (et al.)

Published: May 2021 Journal: European Journal of Pediatrics

A COVID-19 vaccine can be an important key for mitigating the spread of the pandemic, provided that it is accepted by a sufficient proportion of the population. This study investigated parents’ intention to get vaccinated and to have one’s child vaccinated against COVID-19. In May 2020, 612 parents participating with their child in the KUNO-Kids health study completed an online survey.

Journal article

The Effects of the COVID 19 Pandemic on Vaccine Decisions in Pregnant Women

AUTHOR(S)
Hatice Gencer; Sevgi Özkan; Okan Vardar (et al.)

Published: May 2021 Journal: Women and Birth

Pregnancy is an important time for developing attitudes and beliefs about childhood vaccinations. Vaccinations are among the most effective way of preventing some infectious diseases. Discussions on vaccinations have increased due to the Covid-19 pandemic and there is an opportunity to give society correct information on vaccinations. The aim of the study was to determine the opinions of pregnant women on vaccinations in pregnancy and childhood and the effect of the Covid-19 pandemic on these views.

Evidence Synthesis and other Reviews

Understanding COVID-19: are children the key?

AUTHOR(S)
Suz Warner; Alex Richter; Zania Stamataki (et al.)

Published: May 2021 Journal: BMJ Paediatrics Open

The devastating impact of the COVID-19 pandemic on global health and economic stability is immeasurable. The situation is dynamic and fast-evolving, with the world facing new variants of concern which may have immune escape potential. With threatened treatment and preventative strategies at stake, and the prospect of reinfection prolonging the pandemic, it is more crucial than ever to understand the pathogenesis of SARS-CoV-2 infection, which intriguingly disproportionately affects adults and the elderly. Children infected with SARS-CoV-2 remain largely asymptomatic or undergo a transient mild illness. Understanding why children have a milder phenotype and a significant survival advantage may help identify modifiable risk factors in adults.

Journal article

Knowledge and practice to prevent COVID-19 and its associated factors among pregnant women in Debre Tabor Town Northwest Ethiopia, a community-based cross-sectional study

AUTHOR(S)
Alemu Degu Ayele; Gedefaye Nibret Mihretie; Habtamu Gebrehana Belay (et al.)

Published: May 2021 Journal: BMC Pregnancy and Childbirth

Coronavirus disease is now a global concern with the non-availability of antiviral treatment and attacks all groups of the population. Hence, applying preventive measures is the most critical intervention to control the infection. Pregnant women are particularly susceptible to respiratory pathogens because of their immunosuppressive state and physiological adaptive change during pregnancy. Therefore, this study was aimed to assess knowledge and practice to prevent coronavirus disease and its associated factors among pregnant women in Debre Tabor Town.

Journal article

The social determinants of health as predictors of adherence to public health preventive measures among parents and young children during the COVID-19 pandemic: a longitudinal cohort study

AUTHOR(S)
Yulika Yoshida-Montezuma; Charles D. G. Keown-Stoneman; Susitha Wanigaratne (et al.)

Published: May 2021 Journal: Canadian journal of public health

To investigate whether social determinants of health (SDOH) are predictive of adherence to public health preventive measures and to describe changes in adherence over time among parents and children. A longitudinal study was conducted in children aged 0–10 years and their parents through the TARGet Kids! COVID-19 Study in the Greater Toronto Area, Canada (April–July 2020). This study included 335 parents (2108 observations) and 416 children (2632 observations).

Journal article

SARS-CoV-2 vaccination during pregnancy: a complex decision

AUTHOR(S)
Elizabeth Wenqian Wang; Jacqueline G. Parchem; Robert L. Atmar (et al.)

Published: May 2021 Journal: Open Forum Infectious Diseases

As the first severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines passed UK and US regulatory milestones in late 2020 and early 2021, multiple professional societies offered recommendations to assist pregnant and breastfeeding people as they choose whether to undergo vaccination. Despite such guidance, the lack of data describing vaccine safety, immunogenicity, and efficacy in pregnant and breastfeeding people has made this decision challenging for many. However, even considering the paucity of data, the known risks of coronavirus disease 2019 during pregnancy likely outweigh the not yet fully elucidated risks of SARS-CoV-2 vaccines, which have reassuring safety and efficacy profiles among nonpregnant people.

Journal article

Changes in infection-related hospitalizations in children following pandemic restrictions: an interrupted time-series analysis of total population data

AUTHOR(S)
Isobel M. F. Todd; Jessica E. Miller; Stacey L. Rowe

Published: May 2021 Journal: International Journal of Epidemiology

Infectious diseases are a leading cause of hospitalization during childhood. The various mitigation strategies implemented to control the coronavirus disease (COVID-19) pandemic could have additional, unintended benefits for limiting the spread of other infectious diseases and their associated burden on the health care system.

Journal article

Neonatal outcomes of pregnant women with COVID-19 in a developing country setup

AUTHOR(S)
Manas Kumar Nayak; Santosh Kumar Panda; Subhra Snigdha Panda (et al.)

Published: May 2021 Journal: Pediatrics and Neonatology

Current evidence on vertical transmission of severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) and neonatal outcome among exposed newborns is emerging and posing a challenge for preventive interventions. Perinatal transmission to the neonates especially during breastfeeding and rooming in is also relatively unknown. This prospective observational study was conducted in Kalinga Institute of Medical Science (KIMS), Odisha state from 1st May to 20th October 2020. A total of 165 neonates born to SARS-CoV-2 infected mothers were enrolled. Real time polymerase chain reaction (RT PCR) testing was done in first 32 neonates in initial 24 hours of life.

Journal article

COVID-19 in children: clinical manifestations and pharmacological interventions including vaccine trials

AUTHOR(S)
Ramon Galindo; Heather Chow; Chokechai Rongkavilit

Published: May 2021 Journal: Pefiatric Clinics

Children usually present with milder symptoms of COVID-19 as compared with adults. Supportive care alone is appropriate for most children with COVID-19. Antiviral therapy may be required for those with severe or critical diseases. Currently there has been a rapid development of vaccines globally to prevent COVID-19 and several vaccines are being evaluated in children and adolescents. Currently, only Pfizer-BioNTech mRNA vaccine is approved for emergency authorization use in the pediatric population ages 16 years and older.

Research Report

Maternal and perinatal outcomes of pregnant women with SARS-CoV-2 infection at the time of birth in England: national cohort study

AUTHOR(S)
Ipek Gurol-Urganci; Jennifer E. Jardine; Fran Carroll (et al.)

Published: May 2021 Journal: American Journal of Obstetrics and Gynecology

The aim of this study was to determine the association between SARS-CoV-2 infection at the time of birth and maternal and perinatal outcomes. This is a population-based cohort study in England. The inclusion criteria were women with a recorded singleton birth between 29th May 2020 and 31st January 2021 in a national database of hospital admissions. Maternal and perinatal outcomes were compared between pregnant women with a laboratory-confirmed SARS-CoV-2 infection recorded in the birth episode and those without.

Journal article

Care of pediatric patients with diabetes during the COVID-19 pandemic

AUTHOR(S)
Colleen Buggs-Saxton

Published: May 2021 Journal: Pediatric Clinics of North America

This article summarizes clinical observations and management strategies in pediatric type 1 diabetes (T1D) during the COVID-19 pandemic. Despite initial fears that children with diabetes would, similar to adults with diabetes, be at risk for severe COVID-19, the majority of pediatric patients with a history of type 1 diabetes (T1D) who developed COVID-19 had mild disease or were asymptomatic similar to their peers without diabetes. Studies found that pediatric patients with new-onset diabetes often presented with more severe diabetic ketoacidosis (DKA) in part due to both parental anxiety with seeking emergency medical care and systemic barriers to accessing health care during a pandemic. The article also summarizes the use of telemedicine to provide ongoing care for pediatric patients with T1D during the COVID-19 pandemic. Finally, the article highlights important lessons learned about management of pediatric diabetes during the COVID-19 pandemic.

Journal article

Changes in childhood vaccination during the coronavirus disease 2019 pandemic in Japan

AUTHOR(S)
Yuta Aizawa; Tomohiro Katsuta; Hiroshi Sakiyama (et al.)

Published: May 2021 Journal: Vaccine

The coronavirus disease 2019 (COVID-19) pandemic has greatly affected daily life. COVID-19 often causes asymptomatic or mild disease in children; however, delayed routine childhood immunization is a concern, as it could increase the risk of vaccine-preventable disease. No study has evaluated the status of childhood vaccinations in Japan during the COVID-19 pandemic.

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UNICEF Innocenti's Children and COVID-19 Library is a database collecting research from around the world on COVID-19 and its impacts on children and adolescents.

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