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Children and COVID-19 Research Library

UNICEF Innocenti's curated library of COVID-19 + Children research

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151 - 165 of 524
Immunologic response, efficacy, and safety of vaccines against COVID-19 infection in healthy and immunosuppressed children and adolescents aged 2–21 years old: a systematic review and meta-analysis

AUTHOR(S)
Sara Sadeghi; Yasamin Kalantari; Sima Shokri (et al.)

Published: July 2022   Journal: Journal of Clinical Virology
Children and adolescents form a large proportion of societies and play an important role in the transmission of COVID-19. On the other hand, their education, mental and physical wellness, and safety are compromised which makes vaccination a crucial step to return to normal life. In the current systematic review, the COVID-19 vaccination was evaluated in a total of 50,148 children and adolescents in 22 published studies and 5,279 participants in two ongoing clinical trials. The study was registered in the PROSPERO with the ID# CRD42022303615. Data were collected about multiple vaccines including BNT162b2 (Pfizer), mRNA-1273 (Moderna), JNJ-78436735 (Johnson and Johnson), CoronaVac (Sinovac), BBIBP-CorV (Sinopharm), adenovirus type-5-vectored vaccine, ZyCov-D, and BBV152 (COVAXIN). The immune response and efficacy of such vaccines were 96% – 100% in healthy children and adolescents and were also acceptable in those with underlying diseases and suppressed immune systems.
Safety and efficacy of COVID-19 vVaccines in children and adolescents: a systematic review of randomized controlled trials

AUTHOR(S)
Fangyuan Tian; Ruonan Yang; Zhaoyan Chen

Published: June 2022   Journal: Journal of Medical Virology
This paper aims to systematically review and synthesize the safety and efficacy of coronavirus disease-2019 (COVID-19) vaccines in children and adolescents. PubMed, EMBASE, Web of Science, Cochrane Library databases, the International Clinical Trials Registry Platform (ICTRP), the Chinese Clinical Trials Registry (ChiCTR), and ClinicalTrials.gov website were searched to collect accessible randomized controlled trials (RCTs) about the safety and efficacy of human COVID-19 vaccines in children and adolescents until May 1, 2022. Three steps, including duplicate removal, title and abstract screening, and full-text review, were used to screen the studies. The Cochrane risk-of-bias tool for RCTs was used to assess the bias risk of the included studies.
A systematic review and meta-analysis on the preventive behaviors in response to the COVID-19 pandemic among children and adolescents

AUTHOR(S)
Feifei Li; Wei Liang; Ryan E. Rhodes (et al.)

Published: June 2022   Journal: BMC Public Health
The purpose of this review was to synthesize the empirical evidence of relevant studies related to preventive behaviors in response to the COVID-19 pandemic among children and adolescents. Further to this, we aimed to identify the demographic, psychological, and social and environmental correlates of such behaviors. Following PRISMA guidelines, eligible literature was identifed by searching seven databases (PsycINFO, PubMed, MEDLINE, EMBASE, Cochrane Library, PROSPERO registry platform, and ClinicalTrials.gov website) and reference list of included studies and relevant review papers from 1st Jan 2020 to 28th Feb 2021. The standardized mean diference and correlation coefcients r were extracted to estimate the efect sizes. Analyses were conducted using R software.
Changes in adolescent mental and somatic health complaints throughout the COVID-19 pandemic: a three-wave prospective longitudinal study

AUTHOR(S)
Gertrud Sofie Hafstad; Sjur Skjørshammer Sætren; Tore Wentzel-Larsen (et al.)

Published: June 2022   Journal: Journal of Adolescent Health
Measures taken to limit the spread of the COVID-19 may have had unintended consequences for the mental and somatic health of children and adolescents. A nationwide three-wave survey in a representative sample of 12–16 year olds in Norway, with baseline data collected in January 2019 (n = 9,240; 49% girls) and follow-ups in June 2020 (n = 3,564; 49% girls) and June 2021 (n = 3,540; 47% girls). Linear mixed-effects models were used to estimate change and identify predictors thereof in mental and somatic health complaints.
Interrupted access to and use of family planning among youth in a community-based service in Zimbabwe during the first year of the COVID-19 pandemic

AUTHOR(S)
Constancia V. Mavodza; Sarah Bernays; Constance R. S. Mackworth-Young (et al.)

Published: June 2022   Journal: Studies in Family Planning
The COVID-19 pandemic has had serious impacts on economic, social, and health systems, and fragile public health systems have become overburdened in many countries, exacerbating existing service delivery challenges. This study describes the impact of the COVID-19 pandemic on family planning services within a community-based integrated HIV and sexual and reproductive health intervention for youth aged 16–24 years being trialled in Zimbabwe (CHIEDZA). It examines the experiences of health providers and clients in relation to how the first year of the pandemic affected access to and use of contraceptives.
COVID-19 and social policy in contexts of existing inequality: experiences of youth with disabilities in Ethiopia and Jordan

AUTHOR(S)
Kate Pincock; Nicola Jonesa; Kifah Baniodeh (et al.)

Published: June 2022   Journal: Disability & Society
This article explores the social policy implications of the COVID-19 pandemic for adolescents and young people with disabilities in Ethiopia and Jordan. The article draws on qualitative research interviews carried out in person between November and December 2019 and by phone between April and June 2020 with 65 young people with hearing, visual and physical impairments in urban settings in both countries, complemented by interviews with key informants in government and civil society organisations working with young people. Whilst in Jordan social policy on disability is more developed, and in Ethiopia, systems are still embryonic, the COVID-19 pandemic has increased the marginalisation of adolescents and young people with disabilities in both contexts as health, education and social protection systems have been slow to mobilise targeted support and address social exclusion. This article identifies social policy gaps in Ethiopia and Jordan that must be addressed in order to support young people with disabilities during crises.
Long-COVID in children and adolescents: a systematic review and meta-analyses

AUTHOR(S)
Sandra Lopez-Leon; Talia Wegman-Ostrosky; Norma Cipatli Ayuzo del Valle (et al.)

Published: June 2022   Journal: Scientific Reports
The objective of this systematic review and meta-analyses is to estimate the prevalence of long-COVID in children and adolescents and to present the full spectrum of symptoms present after acute COVID-19. It used PubMed and Embase to identify observational studies published before February 10th, 2022 that included a minimum of 30 patients with ages ranging from 0 to 18 years that met the National Institute for Healthcare Excellence (NICE) definition of long-COVID, which consists of both ongoing (4 to 12 weeks) and post-COVID-19 (≥ 12 weeks) symptoms. Random-effects meta-analyses were performed using the MetaXL software to estimate the pooled prevalence with a 95% confidence interval (CI). Heterogeneity was assessed using I2 statistics.
Pediatric and adolescent COVID‐19 vaccination side effects: a retrospective cohort study of Iranian teenage group in 2021

AUTHOR(S)
Nader Tavakoli; Nahid Nafissi; Sima Shokri (et al.)

Published: June 2022   Journal: Journal of Medical Virology
This study aimed to determine the safety and efficacy profile of teenager COVID-19 vaccination. In this retrospective cohort study, contact numbers of parents of teenagers under 18 years of age referred to a teenager vaccination centers in Tehran-Iran to receive the corona vaccine were collected, and the following information was obtained via the phones: demographic information, type of vaccine, and the number of doses received, as well as additional information like complications and required treatments. Eleven thousand forty-two subjects aged 10−18 years, mean age 14.55 ± 1.83 year  including 5374 boys and 5768 girls were investigated.
Associations between fear of COVID-19, dental anxiety, and psychological distress among Iranian adolescents

AUTHOR(S)
Maryam Tofangchiha; Chung-Ying Lin; Janneke F. M. Scheerman (et al.)

Published: June 2022   Journal: BDJ Open volume

The present study evaluated the association of fear of COVID-19 with dental anxiety, oral health-related quality of life (OHRQoL), and psychological distress (depression, anxiety and stress), as well as exploring the mediating role of dental anxiety in the association of fear of COVID-19 with OHRQoL and psychological distress. A cross-sectional study was conducted among adolescents in high schools of Qazvin city (Iran) from March-June 2021, recruited through a two-stage cluster sampling method. All the adolescents completed a self-administered survey assessing (i) fear of COVID-19, (ii) depression, anxiety and stress, (iii) OHRQoL, and (iv) dental anxiety. Structural equation modelling was used to evaluate all the hypothesised associations, and the model fit was estimated.

Awareness, barriers and concerns of adolescents toward the COVID-19 vaccine: a cross-sectional study in Singapore

AUTHOR(S)
Prawira Oka; Benecia Wan Qing Thia; Shyna Zhuoying Gunalan (et al.)

Published: June 2022   Journal: Frontiers in Public Health

COVID-19 vaccination is a key public health measure to mitigate the crippling effects of the pandemic. COVID-19 vaccination began in adults and targeted adolescents at a later stage. However, medical decision-making on its uptake among the latter was unknown, which could be affected by their literacy and concerns about the vaccine. The study aimed to elucidate the awareness, concerns and barriers of adolescents toward the COVID-19 vaccine. A cross-sectional online survey using a self-developed questionnaire was conducted between June to November 2021. The adolescent participants were students from institutes of post-secondary education who were recruited via convenience sampling. The data were collated from an officially approved electronic platform, audited and analyzed. Continuous and categorical variables were expressed as mean (standard deviation) and percentages, respectively.

Safety monitoring of COVID-19 vaccination among adolescents aged 12 to 17 years old in the Republic of Korea

AUTHOR(S)
Seontae Kim; Insob Hwang; Mijeong Ko (et al.)

Published: June 2022   Journal: Osong Public Health and Research Perspectives

This study aimed to disseminate information on coronavirus disease 2019 (COVID-19) vaccine safety among adolescents aged 12 to 17 years in the Republic of Korea. Two databases were used to assess COVID-19 vaccine safety in adolescents aged 12 to 17 years who completed the primary Pfizer-BioNTech vaccination series. Adverse events reported to the web-based COVID-19 vaccination management system (CVMS) and collected in the text message-based system were analyzed.

Exploring innovative teaching approaches to adolescents' sexual and reproductive health and rights education during the COVID-19 pandemic in Oluno Circuit, Oshana region of Namibia

AUTHOR(S)
Anna Niitembu Hako; Petrus Dhiginina Shipalanga

Published: June 2022   Journal: European Journal of Educational Sciences

Access to youth-friendly services is critical to ensuring Sexual and Reproductive Health and Rights (SRHR) and the psychological well-being of adolescents. This qualitative study explored the innovative teaching approaches to adolescents’ sexual and reproductive health and rights education during the COVID-19 pandemic in the Oluno circuit. A sample of 10 Life Skills teachers was purposively selected and individual face to face interviews were conducted. Data was analysed using a thematic approach. The findings revealed that the radio, WhatsApp, recorded audios and handouts were used to engage learners on sexual reproductive health information when schools were closed. It is further established that WhatsApp and the radio were the mainly used methods because they were appropriate and user friendly.

Attitude and acceptance of COVID-19 vaccine in parents and adolescents: a nationwide survey

AUTHOR(S)
Hyunju Lee; Young June Choe; Shinkyeong Kim (et al.)

Published: June 2022   Journal: Journal of Adolescent Health
Coronavirus disease 2019 (COVID-19) vaccines are currently authorized for emergency use in adolescents aged 12–17 years; however, there is concern and uncertainty regarding the safety and necessity of COVID-19 vaccination. A survey was carried out to assess the attitudes and acceptance towards vaccination in adolescents. A nationwide web-based survey was conducted among adolescents aged 12–17 years and their parents between June 29 and July 8, 2021 on a platform provided by the Ministry of Education.
The evaluation of physical activity levels and sleep quality of high school and university students during the COVID-19 pandemic

AUTHOR(S)
Merve Koca Kosova; Sercin Kosova

Published: June 2022   Journal: Journal of Turkish Sleep Medicine
There are major changes in the lifestyles of students with the limitations of the Coronavirus disease-2019 pandemic. This study aimed to determine the physical activity status and sleep quality of high school and university students during the pandemic and to compare the sleep quality findings according to their physical activity status. The data were collected electronically. The short form of the International Physical Activity Questionnaire (IPAQ short form) and the Pittsburgh sleep quality index (PSQI) scale were used. The Kruskal-Wallis test was used for the determination of the difference between the groups, which were separated according to IPAQ scores. The correlation between the metabolic equivalents (METs) obtained from the IPAQ score and PSQI score was evaluated using Spearman’s correlation analysis.
Long COVID in children and young people: uncertainty and contradictions

AUTHOR(S)
Carolyn A. Chew-Graham; Tracy A. Briggs; Binita Kane

Published: June 2022   Journal: British Journal of General Practice

‘Long COVID’ describes both ongoing symptomatic COVID-19 (5–12 weeks after onset) and post-COVID-19 syndrome (≥12 weeks after onset). Long COVID is also a patient-preferred term so will be used throughout this editorial to describe symptoms lasting ≥4 weeks after an acute episode of COVID-19. As the phenomenon of long COVID emerged and came to be recognised, including with the publication of the guideline by the National Institute for Health and Care Excellence, Scottish Intercollegiate Guideline Network, and the Royal College of General Practitioners, there was still limited evidence about whether children and young people could suffer with prolonged symptoms following an acute COVID-19 infection. The general opinion was still that SARS-CoV-2 was a mild infection in the young.

Cite this research | Open access | Vol.: 72 | Issue: 719 | No. of pages: 2 | Language: English | Topics: Health | Tags: adolescent health, child health, COVID-19, infectious disease, pandemic, respiratory diseases | Countries: United Kingdom
151 - 165 of 524

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COVID-19 & Children: Rapid Research Response

UNICEF Innocenti is mobilizing a rapid research response in line with UNICEF’s global response to the COVID-19 crisis. The initiatives we’ve begun will provide the broad range of evidence needed to inform our work to scale up rapid assessment, develop urgent mitigating strategies in programming and advocacy, and preparation of interventions to respond to the medium and longer-term consequences of the COVID-19 crisis. The research projects cover a rapid review of evidence, education analysis, and social and economic policies.