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Children and COVID-19 Research Library

UNDER DEVELOPMENT UNICEF Innocenti's curated library of COVID-19 + Children research

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A study of breastfeeding practices, SARS-CoV-2 and its antibodies in the breast milk of mothers confirmed with COVID-19

AUTHOR(S)
Sicong Peng; Huaping Zhu; Lixia Yang (et al.)

Published: November 2020   Journal: The Lancet Regional Health - Western Pacific
The possibility of 2019 novel coronavirus disease transmission to neonates through breast milk remains unverified. This paper presents the interim results of a longitudinal study being carried out in Hubei province. As of 1 April 2020, 24 mothers confirmed with COVID-19, 19 mothers suspected with COVID-19 but Polymerase chain reaction negative, and 21 mothers without COVID-19 and their neonates have been recruited. Telephone follow-up was conducted to collect information on breastfeeding practices. Forty-four breast milk samples were collected from 16 of the 24 mothers with confirmed COVID-19 for the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) ribonucleic acid (RNA) and antibodies (IgM and IgG) testing.
Caregiver willingness to vaccinate their children against COVID-19: Cross sectional survey

AUTHOR(S)
Ran D. Goldman; Tyler D. Yan; Michelle Seiler (et al.)

Published: November 2020   Journal: Vaccine
More than 100 COVID-19 vaccine candidates are in development since the SARS-CoV-2genetic sequence was published in January 2020. The uptake of a COVID-19 vaccine among children will be instrumental in limiting the spread of the disease as herd immunity may require vaccine coverage of up to 80% of the population. Prior history of pandemic vaccine coverage was as low as 40% among children in the United States during the 2009 H1N1 influenza pandemic. This paper aims to investigate predictors associated with global caregivers’ intent to vaccinate their children against COVID-19, when the vaccine becomes available.
Cite this research | Open access | Vol.: 38 | Issue: 48 | No. of pages: 7668-7673 | Language: English | Topics: Health | Tags: disease control, disease transmission, vaccination, COVID-19 response | Countries: United States
Age-structured model for COVID-19: Effectiveness of social distancing and contact reduction in Kenya

AUTHOR(S)
Mark Kimathi; Samuel Mwalili; Viona Ojiambo (et al.)

Published: October 2020   Journal: Infectious Disease Modelling
Coronavirus disease 2019 is caused by severe acute respiratory syndrome coronavirus 2. Kenya reported its first case on March 13, 2020 and by March 16, 2020 she instituted physical distancing strategies to reduce transmission and flatten the epidemic curve. An age-structured compartmental model was developed to assess the impact of the strategies on COVID-19 severity and burden. Contacts between different ages are incorporated via contact matrices. Simulation results show that 45% reduction in contacts for 60-days period resulted to 11.5–13% reduction of infections severity and deaths, while for the 190-days period yielded 18.8–22.7% reduction. The peak of infections in the 60-days mitigation was higher and happened about 2 months after the relaxation of mitigation as compared to that of the 190-days mitigation, which happened a month after mitigations were relaxed. Low numbers of cases in children under 15 years was attributed to high number of asymptomatic cases. High numbers of cases are reported in the 15–29 years and 30–59 years age bands. Two mitigation periods, considered in the study, resulted to reductions in severe and critical cases, attack rates, hospital and ICU bed demands, as well as deaths, with the 190-days period giving higher reductions.
COVID-19 trends among school-aged children — United States, March 1–September 19, 2020

AUTHOR(S)
Rebecca T. Leeb; Sandy Price; Sarah Sliwa (et al.)

Published: October 2020   Journal: Morbidity and Mortality Weekly Report

Children aged <10 years can transmit SARS-CoV-2 in school settings, but less is known about COVID-19 incidence, characteristics, and health outcomes among school-aged children (aged 5–17 years) with COVID-19. Since March, 277,285 COVID-19 cases in children have been reported. COVID-19 incidence among adolescents aged 12–17 years was approximately twice that in children aged 5–11 years. Underlying conditions were more common among school-aged children with severe outcomes related to COVID-19. Weekly incidence, SARS-CoV-2 test volume, and percentage of tests positive among school-aged children varied over time and by region of the United States. It is important for schools and communities to monitor multiple indicators of COVID-19 among school-aged children and layer prevention strategies to reduce COVID-19 disease risk for students, teachers, school staff, and families. These results can provide a baseline for monitoring trends and evaluating mitigation strategies.

Cite this research | Vol.: 69 | No. of pages: 1410-1415 | Language: English | Topics: Health | Tags: child health, disease control, disease transmission, schools, COVID-19 | Countries: United States
A citizen science facemask experiment and educational modules to improve coronavirus safety in communities and schools

AUTHOR(S)
Sarah E. Eichler; Austin P. Hopperton; Juan José Alava (et al.)

Published: September 2020   Journal: Frontiers in Medicine
There is need to support facemask citizen science and experiential education among children and families as the globe exits from the current lockdown, and teachers and students desire and seek for safe strategies to return to densely-attended schools. COVID-19 is a pandemic respiratory disease that disseminates as infectious respiratory or saliva droplets are released into the environment as people talk, sneeze, and cough. Currently the most publicized methods to prevent local transmission of COVID-19 and promote “droplet safety” in hospitals and communities include hand washing, social distancing, and stay-at-home strategies. In contrast to established benefits for medical masks in hospitals, the benefits of wearing masks or face covers/coverings (hereafter, “facemask”) in the community have been inconsistently debated by the media, creating confusion, and misinformation. Furthermore, high-profile political leaders in countries heavily affected by the pandemic have given misleading signs regarding containment measures associated with COVID-19 increasingly polarizing local communities around arguments on the value of facemasks in promoting public health, which is critically important to incentivize during the emergence of citizens from their lockdowns and during the phase of reopening local economies.
An analysis of child-care and school outbreak data and evidence-based recommendations for opening schools & keeping them open

AUTHOR(S)
Fiona Russell; Kathryn Snow; Margie Danchin (et al.)

Published: September 2020
This report is an analysis of the global literature and available Early Childhood Education and Care (ECEC) and school outbreak data, 25 January 2020 – 31 August 2020. It aims to explore the role of ECEC and schools in transmission of SARS-CoV-2.
Surveillance of COVID-19 school outbreaks, Germany, March to August 2020

AUTHOR(S)
Eveline Otte im Kampe; Ann-Sophie Lehfeld; Silke Buda (et al.)

Published: September 2020   Journal: Eurosurveillance
Mitigation of the coronavirus disease (COVID-19) pandemic in Germany included school closures in early March 2020. After reopening in April, preventive measures were taken in schools. This paper analyses national surveillance system data on COVID-19 school outbreaks during different time periods. After reopening, smaller outbreaks (average: 2.2/week) occurred despite low incidence in the general population. School closures might have a detrimental effect on children and should be applied only cautiously and in combination with other measures.
COVID-19 in children and the role of school settings in COVID-19 transmission
Institution: European Centre for Disease Prevention and Control
Published: August 2020
The aim of this document is to provide an overview of the epidemiology and disease characteristics of COVID-19 in children (0-18 years) in EU/EEA countries and the United Kingdom (UK), and an assessment of the role of childcare (preschools; ages 0-<5 years) and educational (primary and secondary schools; ages 5-18 years) settings in COVID-19 transmission.
Objectives for COVID-19 testing in school settings
Institution: European Centre for Disease Prevention and Control
Published: August 2020
The aim of this document is to provide an overview of major aspects of testing, contact tracing, contact identification and contact follow-up in school settings within the EU/EEA countries and the United Kingdom (UK).
Infection control practices in children during COVID-19 pandemic: differences from adults

AUTHOR(S)
Ilker Devrim; Nuri Bayram

Published: August 2020   Journal: The American Journal of Infection Control
Limited studies have been published on practices and management of Coronavirus Disease 2019 (COVID-19) in children. Despite the fact that COVID-19 rarely caused any severe disease in children, the asymptomatic children might be playing an important role for spreading COVID-19 in healthcare facilities. This review aimed at sharing our experience of how to handle patients with COVID-19 in a pediatric referral and tertiary care hospital to prevent the possible transmissions to the healthcare workers (HCWs).
Cite this research | Open access | Vol.: 48 | Issue: 8 | No. of pages: 933-939 | Language: English | Topics: Health | Tags: child care services, child health, disease control, disease transmission, infectious disease, COVID-19
Characterisation of COVID-19 pandemic in paediatric age group: a systematic review

AUTHOR(S)
Naira M. Mustafa; Laila A. Selim

Published: July 2020   Journal: Journal of Clinical Virology
This article performes a systematic review and meta-analysis to analyse the disease characterisation in paediatric age group including the possibility of vertical transmission to the neonates.
Transmission of SARS-CoV-2: implications for infection prevention precautions
Institution: WHO
Published: July 2020
This document is an update to the scientific brief published on 29 March 2020 entitled “Modes of transmission of virus causing COVID-19: implications for infection prevention and control (IPC) precaution recommendations” and includes new scientific evidence available on transmission of SARS-CoV-2, the virus that causes COVID-19.
Cite this research | No. of pages: 10 | Language: English | Topics: Health | Tags: disease control, disease transmission, infectious disease, COVID-19 | Publisher: WHO
Breastfeeding and COVID-19
Institution: WHO
Published: June 2020
Breastfeeding is the cornerstone of infant and young child survival, nutrition and development and maternal health. The World Health Organization recommends exclusive breastfeeding for the first 6 months of life, followed by continued breastfeeding with appropriate complementary foods for up to 2 years and beyond.
This scientific brief examines the evidence to date on the risks of transmission of COVID-19 from an infected mother to her baby through breastfeeding as well as evidence on the risks to child health from not breastfeeding
A review of COVID-19 in children

AUTHOR(S)
Parisa Khoshnevisasl; Mansour Sadeghzadeh; Sara Sadeghzadeh

Published: May 2020   Journal: Journal of Comprehensive Pediatrics

This study gathers useful information about the virology, pathogenesis, epidemiology, manifestations, diagnosis, and treatment with special consideration of pediatric patients. This review article helps medical caregivers to receive a quick and effective approach to deal with this disease in their practice.



Cite this research | Open access | Vol.: 11 | Issue: 3 | No. of pages: 7 | Language: English | Topics: Health | Tags: child health, disease control, disease transmission, infectious disease, COVID-19, epidemiology
SARS-CoV-2 (COVID-19): What do we know about children? A systematic review

AUTHOR(S)
Nisha Metha; Oliver Mytton; Edward Mullins (et al.)

Published: May 2020   Journal: Clinical Infectious Diseases
This systematic review aims to understand the infection rate, clinical presentation, clinical outcomes and transmission dynamics for SARS-CoV-2, in order to inform clinical and public health measures. Children appear to be less affected by COVID-19 than adults by observed rate of cases in large epidemiological studies. Limited data on attack rate indicate that children are just as susceptible to infection. Data on clinical outcomes are scarce but include several reports of asymptomatic infection and a milder course of disease in young children, though radiological abnormalities are noted. Severe cases are not reported in detail and there are little data relating to transmission.
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UNICEF Innocenti's Children and COVID-19 Library is a database collecting research from around the world on COVID-19 and its impacts on children and adolescents.

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COVID-19 & Children: Rapid Research Response

UNICEF Innocenti is mobilizing a rapid research response in line with UNICEF’s global response to the COVID-19 crisis. The initiatives we’ve begun will provide the broad range of evidence needed to inform our work to scale up rapid assessment, develop urgent mitigating strategies in programming and advocacy, and preparation of interventions to respond to the medium and longer-term consequences of the COVID-19 crisis. The research projects cover a rapid review of evidence, education analysis, and social and economic policies.