Children and COVID-19 Research Library

Polio is a deadly viral disease that has been paralyzing many children in Afghanistan. Despite fundamental efforts, primarily vaccination, to reduce the number of cases in Afghanistan, there are still many children who are deprived of the vaccine every year. Afghanistan is one of the two remaining countries endemic for polio, and the country has undergone various challenges that have hampered the eradication of this disease. The underlying challenges include inaccessibility of unsecured areas, illiteracy, refusal, and, most recently, COVID-19. The country is in the midst of a battle against COVID-19, and polio has almost entirely been neglected.

This document is an update to the scientific brief published on 29 March 2020 entitled “Modes of transmission of virus causing COVID-19: implications for infection prevention and control (IPC) precaution recommendations” and includes new scientific evidence available on transmission of SARS-CoV-2, the virus that causes COVID-19.

Understanding the role of children in the transmission of SARSCoV-2 is urgently required given its policy implications in relation to the reopening of schools and intergenerational contacts. This article conducted a rapid review of studies that investigated the role of children in the transmission of SARS-CoV-2. It synthesized evidence for four categories: 1) studies reporting documented cases of SARS-CoV-2 transmission by infected children; 2) studies presenting indirect evidence on the potential of SARS-CoV-2 transmission by (both symptomatic and asymptomatic) children; 3) studies reporting cluster outbreaks of COVID-19 in schools; 4) studies estimating the proportions of children infected by SARS-CoV-2, and reported results narratively

Latin American and Caribbean (LAC) countries have varied in their responses to the COVID-19 crisis with the majority declaring some form of a state of emergency, and adopting preventive measures to limit transmission, throughout March and April 2020. Restrictions are set to continue in several LAC countries throughout May and June, while others began loosening restrictions by the beginning of May. The LAC region has the highest levels of inequality in the world, with wide gaps in living standards across countries, regions, sectors, and socio-economic spheres. When also added to the persistent, pervasive gender inequality in the region the response to COVID-19 becomes immeasurably more complex.

This systematic review aims to understand the infection rate, clinical presentation, clinical outcomes and transmission dynamics for SARS-CoV-2, in order to inform clinical and public health measures. Children appear to be less affected by COVID-19 than adults by observed rate of cases in large epidemiological studies. Limited data on attack rate indicate that children are just as susceptible to infection. Data on clinical outcomes are scarce but include several reports of asymptomatic infection and a milder course of disease in young children, though radiological abnormalities are noted. Severe cases are not reported in detail and there are little data relating to transmission.