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Children and COVID-19 Research Library

UNICEF Innocenti's curated library of COVID-19 + Children research

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16 - 30 of 134
SARS-CoV-2 vaccines during pregnancy and breastfeeding: a systematic review of maternal and neonatal outcomes

Domenico Umberto De Rose; Guglielmo Salvatori; Andrea Dotta (et al.)

Published: March 2022   Journal: Viruses
This systematic review summarizes current knowledges about maternal and neonatal outcomes following COVID-19 vaccination during pregnancy and breastfeeding.  PubMed, Cochrane Library, and the Education Resources Information Center (ERIC) were searched up to 27 October 2021. The primary outcome was to estimate how many pregnant and lactating women were reported to be vaccinated and had available maternal and neonatal outcomes.
Association between risk perception and acceptance for a booster dose of COVID-19 vaccine to children among child caregivers in China

Chenyuan Qin; Ruitong Wang; Liyuan Tao (et al.)

Published: March 2022   Journal: Frontiers in Public Health

At present, the widespread variants and the weakened immunity provided by vaccines over time have further emphasized the importance of vaccination, boosters, and prevention efforts against COVID-19. Here, this study intends to investigate the acceptability of a booster dose of COVID-19 vaccine among child caregivers, aiming to explore the association between risk perception and child vaccine acceptance. This anonymous, national, cross-sectional survey was conducted for one week from November 12, 2021 in mainland China. The risk perception among child caregivers was assessed based on the Health Belief Model (HBM) and the individuals was equally divided into three levels according to the total preset scores of each perception dimension. Pearson χ2 test was used to compare the differences among participants stratified by sociodemographic characteristics, health status, knowledge factors and risk perception. Univariate and multivariate logistic regression models were performed to explore the associations between risk perception and the acceptance of a booster dose of COVID-19 vaccine.

Seroprevalence of SARS-CoV-2 antibodies in children and adolescents: results from a population-based survey in 10 Colombian cities

Marcela María Mercado-Reyes; Marcela Daza; Angélica Pacheco (et al.)

Published: March 2022   Journal: Global Pediatric Health
Understanding COVID-19 dynamics in Colombia during the first pandemic year (2020) gives important insights surrounding population’s exposure risk and specific susceptibilities. Seroprevalence studies can aid in having a broader understanding of the disease, offering a more inclusive view of the pandemic’s impact across the population. A population-based cross-sectional study to assess antibodies against SARS-CoV-2 in 10 Colombian cities was developed between September and December 2020. Cities were grouped according development typology (Robust (RD), Intermediate (ID) and Incipient (InD)). Detection of total antibodies (IgM + IgG) against SARS-CoV-2 was employed. Univariate Odds Ratios (OR) were estimated for antibody results and selected variables.
Cite this research | Open access | No. of pages: 16 | Language: English | Topics: Health | Tags: child health, COVID-19, epidemiology, immunization, infectious disease, pandemic | Countries: Colombia
Understanding COVID-19 vaccine uptake during pregnancy: ‘hesitance’, knowledge, and evidence-based decision-making

Leigh Ann Simmons; Mackenzie D. M. Whipps; Jennifer E. Phipps (et al.)

Published: March 2022   Journal: Vaccine

A key mitigation strategy to the COVID-19 pandemic has been the development and roll-out of vaccines. However, pregnant and lactating people were not included in initial vaccine trials and this population is hesitant to receive the vaccine, despite contrary recommendations from the American College of Obstetrics and Gynecology and the Centers for Disease Control and Prevention. Understanding the reasons behind this hesitancy is vital to promote vaccine uptake. This study surveyed pregnant people in California from December 2020 to January 2021 (n = 387) to describe cognitions and decision-making regarding COVID-19 vaccination. Using descriptive, regression-based analyses, it examined rates of planned uptake and reasoning among individuals who reported COVID-19 vaccine hesitancy.

COVID-19 vaccine hesitancy among adolescents: cross-ectional school survey in four Chinese cities prior to vaccine availability

Palizhati Rehati; Nubiya Amaerjiang; Liping Yang (et al.)

Published: March 2022   Journal: Vaccines
To address the novel coronavirus disease (COVID-19) pandemic, development and regulatory evaluations have been accelerated for vaccines, authorizing emergency use. To anticipate vaccine preparedness in adolescents, this study analyzed COVID-19 vaccination awareness and willingness to vaccinate before the vaccine became available. It conducted a cross-sectional survey among 9153 (4575 boys, 50%) students with a mean age of 14.2 years old in four cities in China to collect information on demographic characteristics and their COVID-19 vaccination concerns. Multinomial logistic regression was used to analyze the influencing factors of vaccine hesitancy (“not sure”) and resistance (“do not want it”).
Effectiveness and safety of SARS-CoV-2 vaccines among children and adolescents: a systematic review and meta-analysis

Peng Gao; Shan Cai; Qiao Liu (et al.)

Published: March 2022   Journal: Vaccines
The proportion of children and adolescents with COVID-19 had gradually increased according to data reported by WHO. However, there was no meta-analysis of effectiveness and safety of SARS-CoV-2 vaccines in children and adolescents. This paper aimed to provide investigationbased medical evidence and reference recommendations for children and adolescents in regard to SARS-CoV-2 vaccines. It systematically searched PubMed, Embase, and Web of Science from inception to 5 January 2022. RCTs and observational studies that examined the effectiveness and safety were included.
The social gradient in COVID-19 vaccination intentions and the role of solidarity beliefs among adolescents

Alexander Patzin; Hans Dietrich

Published: March 2022   Journal: SSM - Population Health

Vaccines against COVID-19 play a prominent role in the policies enacted to combat the pandemic. However, vaccination rates are lowest among adolescents and young adults. Therefore, research on younger individuals is needed to provide a deeper understanding of social disparities and the motives behind vaccination intentions. This study draws on a sample (N = 4079) of German high school students and graduates. Based on cross-sectional data from March to July 2021 and linear regression models, which are conditioned on personality, risk preferences, and trust, the study analyses social disparities (i.e., gender, parental education and migration background) in vaccination intentions.

Determinants of COVID-19 vaccine hesitancy among parents in Ho Chi Minh City, Vietnam

Giao Huynh; Han Thi Ngoc Nguyen; Khanh Van Tranc

Published: February 2022   Journal: Postgraduate Medicine

COVID-19 vaccines are critical tools to manage the current pandemic. The objective of this study is to assess determinants of COVID-19 vaccine hesitancy among parents in Ho Chi Minh City, Vietnam. A cross-sectional study of parents were performed, who had at least one child aged 5–17 years. The data were collected by a self-report questionnaire, which was based, predominately, on the Health Belief Model (HBM), between January 21 and 20 April 2021. The main outcome of this study aims to investigate the self-reported parental COVID-19 vaccine hesitancy for their children that has been approved by health authorities in Vietnam.

Impact of COVID-19 pandemic on routine vaccination coverage of children and adolescents: a systematic review
Published: February 2022   Journal: Health Science Reports

Scientists and healthcare workers have expressed their concerns on the impacts of the COVID-19 pandemic on vaccination coverage in children and adolescents. Therefore, this study aimed to systematically review the studies addressing this issue worldwide. A systematic search of relevant studies using the keywords was conducted on databases of PubMed, Web of Science, and Cochrane on May 22, 2021. The identified records were imported into EndNote software and underwent a two-phase screening process consisting of title/abstract and full-text screenings against inclusion criteria. The data of the included studies were summarized into a table and the findings were analyzed in a systematic approach.

Association between risk perception and influenza vaccine hesitancy for children among reproductive women in China during the COVID-19 pandemic: a national online survey

Liyuan Tao; Min Du; Jue Liu (et al.)

Published: February 2022   Journal: BMC Public Health

In China, the national prevalence of parental influenza vaccine hesitancy (IVH) during the pandemic of coronavirus disease 2019 (COVID-19), and the association between risk perception and parental IVH are still unclear. This study aimed to explore the association between risk perception and IVH for children among reproductive women in China, a poorly studied area. From December 14, 2020, to January 31, 2021, we conducted a national anonymous online survey on IVH for children among reproductive women in China. We assessed risk perception including perceived susceptibility, severity, barriers, and benefits using the Health Belief Model and then classified each variable into three groups based on tertiles. Logistic regression models were used to calculate the adjusted odds ratio (aOR) of risk perception related to vaccine hesitancy after controlling for sociodemographic characteristics, health status, and knowledge of influenza, among other factors. Additionally, subgroup analysis was performed.

Safety of SARS-CoV-2 vaccination during pregnancy- obstetric outcomes from a large cohort study

Aharon Dick; Joshua I. Rosenbloom; Einat Gutman-Ido (et al.)

Published: February 2022   Journal: BMC Pregnancy and Childbirth

COVID-19 during pregnancy is associated with adverse outcomes for mother and fetus. SARS-CoV-2 vaccination has significantly reduced the risk of symptomatic disease. Several small studies have reported the safety of SARS-CoV-2 vaccination during pregnancy, with no adverse effect on obstetric outcomes. To examine the association between SARS-CoV-2 vaccination during pregnancy and maternal and neonatal outcomes in a large cohort study. Furthermore, to evaluate if timing of vaccination during pregnancy is related to adverse outcomes.

Inequities in COVID-19 vaccination rates among adolescents in Massachusetts: a cross-sectional study

David X. Gao; Lloyd D. Fisher; Donald R. Miller (et al.)

Published: February 2022   Journal: Clinical Infectious Diseases

The COVID-19 pandemic has disproportionately affected more socioeconomically disadvantaged persons and areas. This study sought to determine how certain sociodemographic factors were correlated to adolescents’ COVID-19 vaccination rates in towns and cities (“communities”) in the Commonwealth of Massachusetts. Data on COVID-19 vaccination rates were obtained over a 20-week period from March 30, 2021 to August 10, 2021. Communities’ adolescent (ages 12-19) vaccination rates were compared across quintiles of community-level income, COVID-19 case rate, and proportion of non-Hispanic Black or Hispanic individuals. Other variables included population density and earlier COVID-19 vaccination rates of adolescents and adults, averaged from March 30 to May 11 to determine their effects on vaccination rates on August 10. Linear and logistic regression was used to estimate individual effects of variables on adolescent vaccination rates.

The risk factors and pregnant women's willingness toward the SARS-CoV-2 vaccination in various countries: a systematic review and meta-analysis

Ricvan Dana Nindrea; Dovy Djanas; Warsiti (et al.)

Published: February 2022   Journal: Clinical Epidemiology and Global Health
Pregnant women will benefit from research on immunization during pregnancy because they will have more accurate information on the SARS-CoV-2 vaccine. The purpose of this study was to determine the risk factors and pregnant women's desire to get the SARS-CoV-2 vaccine in various countries. A search of PubMed, ProQuest, and EBSCO for related publications published (January and December 2021) on risk factors and pregnant women's desire to get the SARS-CoV-2 vaccine in various countries. The Pooled Odds Ratio (POR) were calculated using fixed and random-effect analysis. The I-squared formula was used to calculate the heterogeneity. Egger's and Begg's tests were used to identify study bias. STATA 16.0 was used for data analysis.
Medical factors associated with caregiver intention to vaccinate their children against COVID-19

Thao-Ly T. Phan; Paul T. Enlow; Michael K. Wong (et al.)

Published: February 2022   Journal: Vaccine: X

This paper aims to describe medical factors that are associated with caregiver intention to vaccinate their children against COVID-19. It conducted a cross-sectional study of families receiving primary care in a mid-Atlantic pediatric healthcare system, linking caregiver-reported data from a survey completed March 19 to April 16, 2021 to comprehensive data from the child’s EHR.

Factors associated with parental acceptance of COVID-19 vaccination: a multicenter pediatric emergency department cross-sectional analysis

Brigitte M. Baumann; Robert M. Rodriguez; Amy M. DeLaroche (et al.)

Published: February 2022   Journal: Annals of Emergency Medicine

At a time when the COVID19 vaccine was approved for everyone > 12 years of age, this study sought to identify characteristics and beliefs associated with COVID-19 vaccination acceptance. It conducted a cross-sectional survey study of parents of children aged 3-16 years presenting to one of 9 emergency departments from June-August 2021 to assess parental acceptance of COVID-19 vaccines. Using multiple variable regression, it ascertained which factors were associated with parental and pediatric COVID-19 vaccination acceptance.

16 - 30 of 134

UNICEF Innocenti's Children and COVID-19 Library is a database collecting research from around the world on COVID-19 and its impacts on children and adolescents.


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COVID-19 & Children: Rapid Research Response

UNICEF Innocenti is mobilizing a rapid research response in line with UNICEF’s global response to the COVID-19 crisis. The initiatives we’ve begun will provide the broad range of evidence needed to inform our work to scale up rapid assessment, develop urgent mitigating strategies in programming and advocacy, and preparation of interventions to respond to the medium and longer-term consequences of the COVID-19 crisis. The research projects cover a rapid review of evidence, education analysis, and social and economic policies.