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Children and COVID-19 Research Library

UNICEF Innocenti's curated library of COVID-19 + Children research

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1 - 15 of 231
A critical assessment of the potential vertical transmission hypotheses: Implications for research on the early-life infection with COVID-19

AUTHOR(S)
Mengqin Yang; Qiuqin Wang; Yulei Song (et al.)

Published: October 2021   Journal: Placenta
The risk of potential vertical transmission in SARS-CoV-2 infected pregnant women is currently a topic of debate. To explore the correlation between the two, this study searched PubMed, Embase®, and Web of Science for studies on vertical transmission of COVID-19. The quality of the studies was evaluated by the Cochrane risk of bias tool. Detailed information of each included case including methods of delivery, protection measures for mothers and neonates at birth, types of specimens, inspection time, results of testing and feeding patterns was collected to assess the possibility of vertical transmission.
Psychological distress, optimism and emotion regulation among Israeli Jewish and Arab pregnant women during COVID-19

AUTHOR(S)
Miriam Chasson; Taubman Ben-Ari; Salam Abu-Sharkia (et al.)

Published: September 2021   Journal: Journal of Reproductive and Infant Psychology

Pregnancy is a vulnerable period for women, and it is especially so under the worldwide COVID-19 pandemic. Whereas there is some evidence for distress among pregnant women during the outspread of COVID-19, little is known about the second wave of the pandemic. This study therefore sought to examine the contribution of background variables, ethnicity (Jewish, Arab), personal resources (optimism, emotion regulation), and COVID-19-related anxieties to pregnant Israeli women’s psychological distress. A convenience sample of 1127 Israeli women was recruited from 5 July to 7 October 2020.

Stress level and general mental state in Polish pregnant women during COVID-19 pandemic

AUTHOR(S)
Agata Mikolajkow; Krzysztof Małyszczak

Published: September 2021   Journal: Journal of Reproductive and Infant Psychology

COVID-19 pandemic may contribute to mental state worsening. Mental health disorders in pregnancy are known to have adverse outcomes both for mothers and their children. It is the first study in Poland to investigate the impact of the pandemic on stress level and general mental state in pregnant women. Three hundred sixteen pregnant women completed an online survey containing four instruments. The main research questions were investigated with Bayesian regression analyses.

Loneliness and depressive symptoms among pregnant black women during the COVID-19 pandemic

AUTHOR(S)
Carmen Giurgescu; Ana Carolina Wong; Brooke Rengers (et al.)

Published: September 2021   Journal: Western Journal of Nursing Research
This study explored the associations among perceived stress, depressive symptoms, loneliness, and social support during the COVID-19 pandemic; and differences in perceived stress, depressive symptoms, and social support prior to the pandemic and during the pandemic among pregnant Black women. A sample of 33 pregnant Black women who participated in the Biosocial Impact on Black Births (BIBB) and were still pregnant in May–June 2020 were invited to complete an online survey about their experiences during the pandemic. Fifteen women responded very much or somewhat to experiencing stress and anxiety because of the COVID-19 pandemic. Eight women had CES-D scores ≥23, which have been correlated with depression diagnosis. Women who reported higher levels of loneliness during the COVID-19 pandemic also reported higher levels of perceived stress and depressive symptoms and lower levels of social support during the pandemic. Women who reported lower levels of social support during the pandemic also reported higher levels of perceived stress and depressive symptoms during the pandemic. There were no changes in perceived stress, depressive symptoms, or social support prior to the pandemic and during the pandemic.
Preterm birth among women with and without severe acute respiratory syndrome coronavirus 2 infection

AUTHOR(S)
Matthew J. Blitz; Rachel P. Gerber; Moti Gulersen (et al.)

Published: September 2021   Journal: Acta Obstetricia et Gynecologica Scandinavica

Studies directly comparing preterm birth rates in women with and without severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are limited. This study's objective was to determine whether preterm birth was affected by SARS-CoV-2 infection within a large integrated health system in New York with a universal testing protocol. This retrospective cohort study evaluated data from seven hospitals in New York City and Long Island between March 2020 and June 2021, incorporating both the first and second waves of the coronavirus disease 2019 (COVID-19) pandemic in the USA. All patients with live singleton gestations who had SARS-CoV-2 polymerase chain reaction (PCR) testing at delivery were included. Deliveries before 20 weeks of gestation were excluded.

Covid-19 vaccination during the third trimester of pregnancy: rate of vaccination and maternal and neonatal outcomes, a multicentre retrospective cohort study

AUTHOR(S)
M. Rottenstreich; HY Sela; R. Rotem (et al.)

Published: September 2021   Journal: BJOG

This study aims to evaluate the impact of Covid-19 vaccination (Pfizer–BioNTech BNT162b2) during the third trimester of pregnancy on maternal and neonatal outcomes.Women who received two doses of the vaccine were compared with unvaccinated women. Women who were recorded as having disease or a positive Covid-19 polymerase chain reaction (PCR) swab during pregnancy or delivery were excluded from both study groups. Univariate analysis was followed by multivariate logistic regression.

COVID-19 vaccination in pregnancy and lactation: current research and gaps in understanding

AUTHOR(S)
Lydia L. Shook; Parisa N. Fallah; Jason N. Silberman (et al.)

Published: September 2021   Journal: Frontiers in Cellular Infection
The COVID-19 pandemic has demonstrated the urgent need to develop vaccine strategies optimized for pregnant people and their newborns, as both populations are at risk of developing severe disease. Although not included in COVID-19 vaccine development trials, pregnant people have had access to these vaccines since their initial release in the US and abroad. The rapid development and distribution of novel COVID-19 vaccines to people at risk, including those who are pregnant and lactating, presents an unprecedented opportunity to further our understanding of vaccine-induced immunity in these populations. This review aims to summarize the literature to date on COVID-19 vaccination in pregnancy and lactation and highlight opportunities for investigation that may inform future maternal vaccine development and implementation strategies.
The approach of pregnant women to vaccination based on a COVID-19 systematic review

AUTHOR(S)
Sławomir M. Januszek; Anna Faryniak-Zuzak; Edyta Barnaś (et al.)

Published: September 2021   Journal: Medicina
Pregnant women are more likely to develop a more severe course of COVID-19 than their non-pregnant peers. There are many arguments for the safety and efficacy of COVID-19 vaccines in pregnant women. The aim of this study is to conduct a systematic review concerning the approach of pregnant women towards vaccination against COVID-19, with particular regard to determinants of vaccination acceptance.
Cite this research | Open access | Vol.: 57 | Issue: 9 | No. of pages: 11 | Language: English | Topics: Health | Tags: COVID-19, pregnancy, pregnant women, vaccination, vaccination policies
Postpartum women’s psychological experiences during the COVID-19 pandemic: a modified recurrent cross-sectional thematic analysis

AUTHOR(S)
Leanne Jackson; Leonardo De Pascalis; Joanne A. Harrold (et al.)

Published: September 2021   Journal: BMC Pregnancy and Childbirth

COVID-19 has placed additional stressors on mothers during an already vulnerable lifecourse transition. Initial social distancing restrictions (Timepoint 1; T1) and initial changes to those social distancing restrictions (Timepoint 2; T2) have disrupted postpartum access to practical and emotional support. This qualitative study explores the postpartum psychological experiences of UK women during different phases of the COVID-19 pandemic and associated ‘lockdowns’. Semi-structured interviews were conducted with 12 women, approximately 30 days after initial social distancing guidelines were imposed in the UK (22 April 2020). A separate 12 women were interviewed approximately 30 days after the initial easing of social distancing restrictions (10 June 2020). Data were transcribed verbatim, uploaded into NVivo for management and analysis, which followed a recurrent cross-sectional approach to thematic analysis.

Depression in pregnant women with and without COVID-19

AUTHOR(S)
Alissa Papadopoulos; Emily S. Nichols; Yalda Mohsenzadeh (et al.)

Published: September 2021   Journal: BJPsych Open
Evidence suggests that pregnant women who test positive for COVID-19 may develop more severe illness than non-pregnant women and may be at greater risk for psychological distress. The relationship between COVID-19 status (positive, negative, never tested) and symptoms of depression was examined in a survey study (May to September 2020) of pregnant women (n = 869). Pregnant women who reported testing positive for COVID-19 were significantly more likely to report depressive symptoms compared with women who tested negative (P = 0.027) and women who were never tested (P = 0.005). Findings indicate that pregnant women who test positive for COVID-19 should be screened and monitored for depressive symptoms.
Global research priorities for COVID-19 in maternal, reproductive and child health: Results of an international survey

AUTHOR(S)
Melanie Etti; Jackeline Alger; Sofía P. Salas (et al.)

Published: September 2021   Journal: Plos One

The World Health Organization’s “Coordinated Global Research Roadmap: 2019 Novel Coronavirus” outlined the need for research that focuses on the impact of COVID-19 on pregnant women and children. More than one year after the first reported case significant knowledge gaps remain, highlighting the need for a coordinated approach. To address this need, the Maternal, Newborn and Child Health Working Group (MNCH WG) of the COVID-19 Clinical Research Coalition conducted an international survey to identify global research priorities for COVID-19 in maternal, reproductive and child health. This project was undertaken using a modified Delphi method. An electronic questionnaire was disseminated to clinicians and researchers in three different languages (English, French and Spanish) via MNCH WG affiliated networks. Respondents were asked to select the five most urgent research priorities among a list of 17 identified by the MNCH

Covid-19 infection in pregnant women in Dubai: a case-control study
Published: September 2021   Journal: BMC Pregnancy and Childbirth

Whilst the impact of Covid-19 infection in pregnant women has been examined, there is a scarcity of data on pregnant women in the Middle East. Thus, the aim of this study was to examine the impact of Covid-19 infection on pregnant women in the United Arab Emirates population. A case-control study was carried out to compare the clinical course and outcome of pregnancy in 79 pregnant women with Covid-19 and 85 non-pregnant women with Covid-19 admitted to Latifa Hospital in Dubai between March and June 2020.

Effect of knowledge acquisition on gravida’s anxiety during COVID-19

AUTHOR(S)
Ying Huang; Weiwei Bian; Yingting Han

Published: September 2021   Journal: Sexual & Reproductive Healthcare

Pregnant women in China are among those most affected by COVID-19. This article assesses Chinese pregnant women’s COVID-19 and pregnancy knowledge levels, including the modality through which such knowledge was acquired, the degree of difficulty in acquiring the knowledge, the means of confirming the accuracy of the knowledge, and difficulties in seeking help from people who possess relevant medical knowledge. The Mantel-Haenszel chi-square test was used to assess trends in binomial proportions. Multivariable binary logistic regression was performed to identify the association between knowledge acquisition and anxiety among pregnant women.

Being in the shadow of the unknown — Swedish women’s lived experiences of pregnancy during the COVID-19 pandemic, a phenomenological study

AUTHOR(S)
Karolina Linden; Nimmi Domgren; Mehreen Zaigham (et al.)

Published: September 2021   Journal: Women and Birth

The COVID-19 pandemic has had a profound effect on the emotional well-being of expecting mothers. Sweden’s unique strategy for managing COVID-19 involved no national lockdown. Emphasis was instead placed on limiting crowding and asking citizens to practice social distancing measures.This study aimed to gain a deeper understanding of how women not infected by SARS-CoV-2 experienced pregnancy during the COVID-19 pandemic in Sweden. This was a qualitative study with a reflective lifeworld approach. Fourteen women that had not contracted COVID-19 and who were pregnant during the first and second wave of the pandemic were interviewed. Data were analysed with a phenomenological reflective lifeworld approach.

A cross-sectional analysis to evaluate knowledge, attitude and practices among pregnant women during COVID-19 pandemic

AUTHOR(S)
Tarang P. Kaur; Anubhuti Rana; Vanamail Perumal (et al.)

Published: September 2021   Journal: The Journal of Obstetrics and Gynecology of India

This study aimed to assess knowledge, attitude and practices (KAP) towards COVID-19 among pregnant women at a tertiary care hospital. This was a questionnaire-based cross-sectional analysis pertaining to COVID-19 which was conducted at a tertiary care obstetric facility in India among 200 consecutive consenting pregnant women. They were assessed for demographic details and KAP score (knowledge—17 questions, attitude—9 questions and practice—8 questions). Analysis of data was done using Statistical Package for the Social Sciences (SPSS) version 25.0.

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UNICEF Innocenti's Children and COVID-19 Library is a database collecting research from around the world on COVID-19 and its impacts on children and adolescents.

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COVID-19 & Children: Rapid Research Response

UNICEF Innocenti is mobilizing a rapid research response in line with UNICEF’s global response to the COVID-19 crisis. The initiatives we’ve begun will provide the broad range of evidence needed to inform our work to scale up rapid assessment, develop urgent mitigating strategies in programming and advocacy, and preparation of interventions to respond to the medium and longer-term consequences of the COVID-19 crisis. The research projects cover a rapid review of evidence, education analysis, and social and economic policies.