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Children and COVID-19 Research Library

UNICEF Innocenti's curated library of COVID-19 + Children research

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181 - 195 of 231
Future vaccinations in pregnancy

AUTHOR(S)
D. Vress

Published: March 2021   Journal: Best Practice & Research Clinical Obstetrics & Gynaecology

Vaccination in pregnancy provides an important opportunity to target illnesses that are known to impact particularly on pregnant women, fetal development and cause newborn illness. The ability to create antibodies via safe vaccination that cross the placenta can provide protection against maternal, congenital and newborn infection. There are currently multiple vaccines being developed which have direct benefits for pregnant women and their newborns. Group B Streptococcus, Respiratory Syncytial Virus, Cytomegalovirus, Zika, Ebola, Malaria and coronavirus SARS-CoV-2 are all being researched with the view to developing a safe vaccine available for pregnant women. There is also an increased movement towards including pregnant women in vaccine development and trials, challenging the historical, ethical and medicolegal arguments against their involvement in such research.

Outcomes of newborns to mothers with COVID-19

AUTHOR(S)
K. Ghema; M. Lehlimi; H. Toumi (et al.)

Published: March 2021   Journal: Infectious Diseases Now

Coronavirus disease 2019 (COVID-19) has spread rapidly across the world. Given the sharply increased infection rate, the number of pregnant women and children with COVID-19 is correspondingly on the rise. SARS-CoV-2 infection is transmitted through droplets; though hypothesized, other transmission routes have not been confirmed. As of now, it remains unclear whether and how SARS-CoV-2 can possibly be transmitted from the mother to the fetus. This study examines the medical records of 30 neonates born to women with COVID-19, the objective being to provide documented information on maternal-child transmission and infant outcomes.

Maintaining maternal–newborn safety during the COVID-19 pandemic

AUTHOR(S)
Nancy A. Patric; Teresa S. Johnson

Published: March 2021   Journal: Nursing for Women's Health
COVID-19, the disease caused by the SARS-CoV-2 virus, was declared a global pandemic by the World Health Organization on March 11, 2020. In addition to older individuals and those with underlying chronic health conditions, maternal and newborn populations were also identified as being at greater risk. It became critical for hospitals and clinicians to maintain the safety of individuals in the facility and minimize the transmission of COVID-19 while continuing to strive for optimized outcomes by providing family-centered care. Rapid change during the pandemic made it appropriate to use the plan–do–study–act (PDSA) cycle to continually evaluate proposed and standard practices. Our team established an obstetric COVID-19 unit for women and newborns, developed guidelines for visitation and for the use of personal protective equipment, initiated universal COVID-19 testing, and provided health education to emphasize shared decision making.
Midwives’ experiences of providing maternity care during the COVID-19 pandemic in Australia

AUTHOR(S)
Zoe Bradfield; Yvonne Hauck; Caroline S. E. Homer (et al.)

Published: March 2021   Journal: Women and Birth
The COVID-19 pandemic has required rapid and radical changes to the way maternity care is provided in many nations across the world. Midwives provide care to childbearing women across the continuum and are key members of the maternity workforce in Australia. This paper aims to explore and describe midwives’ experiences of providing maternity care during the COVID-19 pandemic in Australia.
Impact of SARS-CoV-2 on the clinical outcomes and placental pathology of pregnant women and their infants: a systematic review

AUTHOR(S)
Irina Oltean; Jason Tran; Sarah Lawrence (et al.)

Published: March 2021   Journal: Heliyon
Pregnant women are susceptible to viral infections due to physiological changes such as cell-mediated immunity. No severe adverse pregnancy or neonatal outcomes have been consistently reported in 2019 novel coronavirus disease (COVID-19) positive pregnancy cases. There are controversies around the role of COVID-19 in pregnancy. A systematic review was conducted to examine clinical maternal and neonatal clinical outcomes. Studies were included if they reported SARS-CoV-2 infection among pregnant women and/or COVID-19 positive neonates as validated by positive antibody testing or viral testing using polymerase chain reaction. Case series, case reports, case-control studies, and comparative studies were included. Eight hundred and thirty-seven records were identified, resulting in 525 records for level I screening. Forty-one were included after full-text review.
Influence of SARS-COV-2 during pregnancy: a placental view

AUTHOR(S)
Marcos Aurélio Santos da Costa; Diana Babini Lapa de Albuquerque Britto; Jennyfer Martins de Carvalho (et al.)

Published: March 2021   Journal: Biology of Reproduction
Since the beginning of the current coronavirus outbreak (COVID-19), there has been great concern over a disease that has spread rapidly in several countries worldwide, with the result of several deaths, including deaths of pregnant women. Therefore, the aim of this study was to conduct a literature review on placental changes in infected pregnant women and/or asymptomatic carriers of COVID-19 during pregnancy, aiming at the possible vertical transmission. A systematic collection was carried out on the effects of that COVID-19 can cause directly and/or indirectly to pregnancy and the placenta in the following databases: Pubmed, Science Direct, Scielo, Lilacs, and Web of Science.
A systematic review of 571 pregnancies affected by COVID-19

AUTHOR(S)
Leila Karimi; Amir Vahedian-Azimi; Somayeh Makvandi (et al.)

Published: March 2021   Journal: Clinical, Biological and Molecular Aspects of COVID-19
The outbreak of the novel coronavirus 2019 (COVID-19) disease has been severe and a cause for major concern around the world. Due to immunological and physiological changes during pregnancy, pregnant women have a higher risk of COVID-19 morbidity and mortality. The aim of this study was to collect and integrate the results of previous studies to get an accurate representation and interpretation of the clinical symptoms, laboratory and radiological findings, and characteristics of pregnant women with COVID-19.
The 2019 novel Coronavirus disease in pregnancy: a systematic review

AUTHOR(S)
Somayeh Makvandi; Mitra Mahdavian; Goli Kazemi-Nia (et al.)

Published: March 2021   Journal: Clinical, Biological and Molecular Aspects of COVID-19
In December 2019, a respiratory disease caused by a coronavirus called SARS-CoV-2 (COVID-19) began in Wuhan, China, and quickly became a pandemic. In such situations, pregnant women are suspected of being among the vulnerable groups. The aim of this study was to report clinical symptoms, laboratory findings, and obstetrical complications, maternal, fetal, and neonatal complications of COVID-19 infection in pregnant women. We searched the Cochrane library, MEDLINE/PubMed, and Web of Sciences from their inception to April 5, 2020. Any study involving pregnant women with COVID-19 which evaluated the effect of the disease on pregnancy outcomes and fetal and neonatal complications was included in the study.
COVID‐19 guidelines for pregnant women and new mothers: a systematic evidence review

AUTHOR(S)
Madeline A. Di Lorenzo; Sarah O'Connor; Caroline Ezekwesili (et al.)

Published: March 2021   Journal: International journal of gynaecology and obstetrics

Nearly a year after COVID-19 was initially detected, guidance for pregnant and new mothers remains varied. The goal of this systematic review is to summarize recommendations for three areas of maternal and fetal care - breastfeeding, post-partum social distancing, and decontamination. We searched PubMed, Embase and Web of Science spanning from inception to November 09, 2020.

The role of pandemic‐related pregnancy stress in preference for community birth during the beginning of the COVID‐19 pandemic in the United States

AUTHOR(S)
Heidi Preis; Brittain Mahaffey; Marci Lobel

Published: March 2021   Journal: Birth
The COVID‐19 pandemic introduced unparalleled uncertainty into the lives of pregnant women, including concerns about where it is the safest to give birth, while preserving their rights and wishes. Reports on the increased interest in community births (at home or in birth centers) are emerging. The purpose of this project was to quantitatively investigate psychological factors related to this birth preference.
Are COVID-19 vaccines safe in pregnancy?

AUTHOR(S)
Victoria Male

Published: March 2021   Journal: Nature Reviews Immunology
As the COVID-19 vaccination programme starts to be rolled out, many young women are hesitant to accept the vaccine, citing concerns about fertility. Meanwhile, those offered the vaccine during pregnancy must decide whether they will accept, even though pregnant people were excluded from the clinical trials. Data on accidental pregnancies that occurred during the trials and, increasingly, outcomes in pregnant people who receive the vaccine can help these groups to make informed decisions.
Sexual function, mental health, and quality of life under strain of COVID-19 pandemic in Iranian pregnant and lactating women: a comparative cross-sectional study

AUTHOR(S)
Negin Mirzaei; Shahideh Jahanian Sadatmahalleh; Mahnaz Bahri Khomami (et al.)

Published: March 2021   Journal: Health and Quality of Life Outcomes volume
The impact of COVID-19 pandemic on mental health of pregnant and lactating women is unclear. This study aimed to assess the impact of COVID-19 on psychological health, sexual function, and quality of life (QoL) in Iranian pregnant and lactating women and compare the results with non-pregnant/non-lactating women.
The lived experiences of pregnant women during COVID-19 pandemic: a descriptive phenomenological study

AUTHOR(S)
Forough Mortazavi; Fatemeh Ghardashi

Published: March 2021   Journal: BMC Pregnancy and Childbirth
With the onset of the COVID-19 epidemic, pregnancy and childbirth for women are taking place in unusual circumstances. We explored the lived experiences of pregnant women during the COVID-19 pandemic to better understand their experience of pregnancy so that better support could be provided.
Infant outcomes and maternal COVID-19 status at delivery

AUTHOR(S)
Kinga Zgutka; Kaninghat Prasanth; Shirley Pinero-Bernardo (et al.)

Published: March 2021   Journal: Physicians Weekly
This study aims to compare clinical characteristics and outcomes of infants born to COVID-19 to non COVID-19 mothers at delivery in a community hospital in Queens, New York. Case-control study conducted March 15 to June 15, 2020. Cases were infants born to mothers with laboratory-confirmed COVID-19 infection at delivery. The infant of non COVID-19 mother born before and after each case were selected as controls.
Management and perspective of Coronavirus disease 2019 (COVID-19), pregnancy, and hypercoagulability

AUTHOR(S)
Umair Nasir; Sarfraz Ahmad

Published: March 2021   Journal: SN comprehensive clinical medicine
The modern-day pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has spread rapidly. There is limited data about the effects of the virus on pregnant women, even in women who were infected by other strains of coronavirus such as severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS). After reviewing numerous articles published in the peer-reviewed journals and other authentic sources, this mini-review evaluated various key clinical and laboratory aspects of coronavirus disease 2019 (COVID-19) in relation to pregnancy.
181 - 195 of 231

UNICEF Innocenti's Children and COVID-19 Library is a database collecting research from around the world on COVID-19 and its impacts on children and adolescents.

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COVID-19 & Children: Rapid Research Response

UNICEF Innocenti is mobilizing a rapid research response in line with UNICEF’s global response to the COVID-19 crisis. The initiatives we’ve begun will provide the broad range of evidence needed to inform our work to scale up rapid assessment, develop urgent mitigating strategies in programming and advocacy, and preparation of interventions to respond to the medium and longer-term consequences of the COVID-19 crisis. The research projects cover a rapid review of evidence, education analysis, and social and economic policies.