CONNECT
search advanced search
UNICEF Innocenti
Office of Research-Innocenti
search menu

Children and COVID-19 Research Library

UNDER DEVELOPMENT UNICEF Innocenti's curated library of COVID-19 + Children research

RESULTS:   5     SORT BY:
Prev 1 Next

UNICEF Innocenti Publication  
UNICEF Publication  
Open Access  
JOURNAL ACCESS FOR UNICEF STAFF CONTACT US
1 - 5 of 5
|First Prev 1 Next Last|
Coronavirus disease 2019 (COVID-19) in children and/or adolescents: a meta-analysis

AUTHOR(S)
Alessandro Mantovani; Elisabetta Rinaldi; Chiara Zusi; et al.

Published: June 2020   Nature Paediatric Research
This review systematically researched in PubMed, Scopus and Web of Science databases observational studies describing COVID-19 in children and/or adolescents until April 11, 2020. Data regarding clinical and radiological features were extracted from eligible studies and meta-analysis was performed using random-effects modeling. The study finds that children and/or adolescents tend to have a mild COVID-19 course with a good prognosis.
Compared to adults, children and/or adolescents tend to have a mild COVID-19 course with a good prognosis.
COVID-19 in Children and Adolescents in Europe: A Multinational, Multicentre Cohort Study

AUTHOR(S)
Petra Prunk; Veronika Osterman; Uros Krivec; et al.

Published: June 2020   The Lancet Child & Adolescent Health
To date, few data on paediatric COVID-19 have been published, and most reports originate from China. This study aimed to capture key data on children and adolescents with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection across Europe to inform physicians and health-care service planning during the ongoing pandemic.
COVID-19 in Children: An Ample Review

AUTHOR(S)
Ioana M Ciuca

Published: June 2020   Risk management and healthcare policy
The aim of this review was to describe the current knowledge about coronavirus disease 2019 (COVID-19, which is caused by severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2]) in children, from epidemiological, clinical, and laboratory perspectives, including knowledge on the disease course, treatment, and prognosis. An extensive literature search was performed to identify papers on COVID-19 (SARS-CoV-2 infection) in children, published between January 1, 2020 and April 1, 2020. There were 44 relevant papers on COVID-19 in children. The results showed that COVID-19 occurs in 0.39–12.3% of children. Clinical signs and symptoms are comparable to those in adults, but milder forms and a large percentage of asymptomatic carriers are found among children. Elevated inflammatory markers are associated with complications and linked to various co-infections. Chest computed tomography (CT) scans in children revealed structural changes similar to those found in adults, with consolidations surrounded by halos being somewhat specific for children with COVID-19. The recommended treatment includes providing symptomatic therapy, with no specific drug recommendations for children. The prognosis is much better for children compared to adults. This review highlights that COVID-19 in children is similar to the disease in the adult population, but with particularities regarding clinical manifestations, laboratory test results, chest imaging, and treatment. The prognosis is much better for children compared to adults, but with the progression of the pandemic; the cases in children might change in the future.
Resistance of children to Covid-19. How?

AUTHOR(S)
Alain Fischer

Published: May 2020   Nature Mucosal Immunology
Both resistance to infection and resistance to disease appear to be much stronger in children than in adults. The apparent resistance to infection might actually reflect a more rapid clearance of the virus so that the chance to detect cases is diminished. Future studies on seropositivity prevalence should help to distinguish between these possibilities. Of note the increased male to female ratio as observed in adult Covid-19 patients (6 to 4) is also observed in children. Finally, children below the age of 1 year are over-represented in pediatric Covid-19 cohorts with a higher risk of fatality compared with children above the age of 1.
Pediatric COVID-19: Systematic review of the literature

AUTHOR(S)
Patel Neha

Published: May 2020   American Journal of Otolaryngology
A systematic review of the literature was performed to gain insight into pediatric COVID-19 epidemiology. Specifically, Pubmed and Google Scholar databases were searched to identify any relevant article with a focus on Pediatric Covid 19, Pediatric Covid-19, Pediatric SARS-COV-2, and Pediatric Coronavirus 19. Results show that, in contrast to adults, most infected children appear to have a milder course and have better outcomes overall. Additional care may be needed for children with comorbidities and younger children. This review also suggests that unilateral CT chest imaging findings were seen in 36.4% pediatric COVID-19 patients. This is particularly concerning as the work-up of pediatric patients with cough may warrant a bronchoscopy to evaluate for airway foreign bodies. Extra precautions need to be taken with personal protective equipment for these cases, as aerosolizing procedures may be a method of viral transmission.
Cite this research | Open access | Vol.: 41 | Issue: 5 | Language: English | Tags: child health, respiratory diseases, COVID-19, epidemiology, multi-country | Topics: Health
1 - 5 of 5
|First Prev 1 Next Last|

UNICEF Innocenti's Children and COVID-19 Library is a database collecting research from around the world on COVID-19 and its impacts on children and adolescents. Learn more.

LEARN MORE ABOUT THE DATABASE

Subscribe to updates on new research about COVID-19 & children

SIGN UP

Share:

facebook twitter linkedin google+ reddit print email
Campaign Campaign

COVID-19 & Children: Rapid Research Response

UNICEF Innocenti is mobilizing a rapid research response in line with UNICEF’s global response to the COVID-19 crisis. The initiatives we’ve begun will provide the broad range of evidence needed to inform our work to scale up rapid assessment, develop urgent mitigating strategies in programming and advocacy, and preparation of interventions to respond to the medium and longer-term consequences of the COVID-19 crisis. The research projects cover a rapid review of evidence, education analysis, and social and economic policies.