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AUTHOR(S) Bi Ze; Bin Chen; Xiaoshan Ji (et al.)
Coronavirus disease 2019 (COVID-19) has been a most important global issue since December 2019. Although for children, the clinical course of COVID-19 is milder, it may still cause a multi-system inflammatory syndrome and has rendered 22,000 deaths among children and young people. The objective of this review is to provide an up-to-date information about COVID-19 related mortality and relevant risk factors in children and young people. This study provides a narrative review of COVID-19 related mortality and relevant risk factors in children and young people. Electronic searches for studies were conducted using PubMed and Web of Science, with a date time up to April 22, 2022. 22, 2022. Only publications in English were included.
AUTHOR(S) Catherine Campos; Samantha Prokopich; Hal Loewen (et al.)
AUTHOR(S) Tracy K. Y. Wong; Tyler Colasante; Tina Malti
AUTHOR(S) Erik J. Nelson; Ella Cook; Megan Pierce (et al.)
Pulmonary hypertension (PH) is a serious and life-threatening disease characterized by elevated mean arterial pressure and pulmonary vascular resistance. COVID-19 may exacerbate PH, as evidenced by higher mortality rates among those with PH. The objective of this study was to understand the unique burdens that the COVID-19 pandemic has placed upon families of children living with PH. Participants were recruited online through the “Families of children with pulmonary hypertension” Facebook group and asked to complete a survey about their experiences during the COVID-19 pandemic.
AUTHOR(S) M. Jahangir Alam
AUTHOR(S) Colleen C. Schreyer; Irina A. Vanzhula; Angela S. Guarda
The COVID-19 pandemic has been associated with increased hospitalization rates and worsened symptom severity in patients with eating disorders (ED), but most studies focused exclusively on adolescents. Further, research evaluating the impact of COVID-19 on response to inpatient treatment for ED is limited. This study aimed to compare demographic characteristics, symptom severity at admission, and discharge outcomes for adult and adolescent inpatients with EDs admitted before and after onset of the COVID-19 pandemic. The post-COVID cohort was expected to report elevated symptomatology and poorer response to treatment compared to the pre-COVID cohort and this effect was expected to be amplified for adolescents. Patients were consecutively hospitalized adults and adolescents treated in a specialized behavioral integrated inpatient-partial hospitalization program for eating disorders between March 2018 and March 2022 (N = 261).
AUTHOR(S) Maria C. L. Oliveira; Enrico A. Colosimo; Mariana A. Vasconcelos (et al.)
There have been conflicting reports on the relationship between asthma and COVID-19 severity. This study aimed to compare the risk of death among children with asthma and healthy peers hospitalized due to COVID-19. It carried out an analysis of all pediatric patients 2–19 years of age with asthma and COVID-19 registered in Influenza Epidemiological Surveillance Information System-Gripe, a Brazilian nationwide surveillance database, between February 2020 and March 2022. The primary outcome was time to death, which was evaluated considering discharge as a competitive risk using the cumulative incidence function.
AUTHOR(S) Bohee Lee; Grace Lewis; Eldad Agyei-Manu (et al.)
The Joint Committee on Vaccination and Immunisation in the United Kingdom requested an evidence synthesis to investigate the relationship between asthma and coronavirus disease 2019 (COVID-19) outcomes. This study conducted a systematic review and meta-analysis to summarise evidence on the risk of severe COVID-19 outcomes in people with uncontrolled asthma or markers of asthma severity.
AUTHOR(S) Hyowon Choi; Eun Jung Lee; Yeon-Soon Ahn (et al.)
Research of coronavirus disease (COVID-19) effects on newborns is ongoing. But the research of specific variant’s effects is none. This study analyzed the effects of the Omicron variant on the perinatal outcomes of full-term newborns during the Omicron wave period. Between December 2021 and April 2022, this study was conducted on all newborns who visited a single center. We investigated due to the Omicron maternal infection maternal pregnancy complications, delivery methods, birth week, Apgar scores, neonatal resuscitation program requirement, whether respiratory support was required until 12 h after childbirth, suspicious infectious status, and mortality depending on maternal Omicron infection.
AUTHOR(S) Sandra Cerar; Vesna Pirnovar
This study aimed to compare the occurrence of lower respiratory tract infections caused by respiratory syncytial virus in the neonatal population in the years before and during the COVID-19 pandemic. Cases of newborns, hospitalized due to viral lower respiratory tract infection from 2015 to 2020, were analyzed retrospectively, and compared according to cause (respiratory syncytial virus, non-respiratory syncytial virus) and treatment requirements before (2015−2019) and after (2020) the outbreak of the COVID-19 pandemic.
AUTHOR(S) Soha Jameel Ashoor; Luay Abdullah Alqurashi; Mariam Ali Hussain (et al.)
AUTHOR(S) Stephanie Chow Garbern; Pryanka Relan; Gerard M. O’Reilly (et al.)
Severe acute respiratory infections (SARIs) remain a leading cause of death globally, particularly in low- and middle-income countries (LMICs). Early intervention is critical, considering the potential for rapid decompensation in patients with SARIs. We aimed to evaluate the impact of acute and emergency care interventions on improving clinical outcomes in patients >10 years old with SARIs in LMICs. A systematic literature search was performed in PubMed, Global Health, and Global Index Medicus databases to identify peer-reviewed studies containing SARI, LMICs, and emergency care interventions. Studies published prior to November 2020 focusing on patients >10 years old were included. A narrative synthesis was performed due to the heterogeneity of identified articles. Risk of bias was assessed using the Risk of Bias 2 and Risk of Bias In Non-Randomized Studies of Interventions tools.
AUTHOR(S) Mahmoud M. M. Abdel-Salam
AUTHOR(S) Emily Robbins; Steven Daoud; Seleshi Demissie (et al.)
Atopy and allergic asthma have been found to be protective against coronavirus disease (COVID-19) in adults but have not been studied in children. This study aimed to identify whether children and adolescents with asthma had less severe disease and lower morbidity from COVID-19 than their counterparts without asthma. This was a retrospective chart review from March 1, 2020, through January 31, 2021. Charts were eligible for inclusion if patients were over 6 years of age and below 20 years of age and tested positive for COVID-19 by PCR or antigen testing or were COVID-19 antibody positive when they presented to the emergency department (ED). Patients were grouped according to disease severity and divided into two groups, those with asthma and those without. A total of 1,585 patients were included—1,492 without asthma and 93 with asthma.
AUTHOR(S) Pinjia Wang; Yidan Xu; Zhe Su (et al.)
UNICEF Innocenti's Children and COVID-19 Library is a database collecting research from around the world on COVID-19 and its impacts on children and adolescents.
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